Abstracts tagged "Ankylosing spondylitis (AS) and spondylarthritis"

Abstract Number: 2063 • 2018 ACR/ARHP Annual Meeting
Early Injection of TNF Inhibitor Prevents Spinal Inflammation and Deformity in Curdlan-Induced Spondyloarthritis Animal Model
Doo-Ho Lim¹, Eun-Ju Lee², Seokchan Hong², Yong-Gil Kim², Chang Keun Lee² and Bin Yoo², ¹Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Ulsan University Hospital, Ulsan, Korea, Republic of (South), ²Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea, Republic of (South)
Background/Purpose: TNF inhibitors are highly efficient in controlling disease activity and improving functional outcomes as well as quality of life in most ankylosing spondylitis patients;…
Abstract Number: 578 • 2017 ACR/ARHP Annual Meeting
Added Value of Biomarkers Compared to Routine Clinical Parameters for the Prediction of Radiographic Spinal Progression in Axial Spondyloarthritis
Lorraine Tietz¹, Lien Le², Agnes Hartl¹, Martin Rudwaleit^1,3, Joachim Sieper¹, Ulrich Mansmann² and Denis Poddubnyy^1,4, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Ludwig-Maximilian University, Munich, Germany, ³Klinikum Bielefeld Rosenhöhe, Bielefeld, Germany, ⁴German Rheumatism Research Centre, Berlin, Germany
Background/Purpose: Structural damage in the spine is an important determinant of the functional status and spinal mobility in axial spondyloarthritis (axSpA). Already present syndesmophytes, elevated…
Abstract Number: 1510 • 2017 ACR/ARHP Annual Meeting
Similarities and Differences between Osteitis Condensans Ilii and Axial Spondyloarthritis Patients Presenting with Chronic Back Pain in a Rheumatology Setting
Henning Weineck¹, Joachim Listing², Torsten Diekhoff¹, Kay-Geert Hermann¹, Joachim Sieper¹ and Denis Poddubnyy^1,2, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²German Rheumatism Research Centre, Berlin, Germany
Background/Purpose: Osteitis condensans ilii (OCI) is regarded as a non-inflammatory disorder, which is considered to be induced by mechanical stress (e.g., by pregnancy and delivery).…
Abstract Number: 978 • 2015 ACR/ARHP Annual Meeting
Continuous Versus on Demand Treatment of Ankylosing Spondylitis with Diclofenac over 2 Years Does Not Prevent Radiographic Progression of the Spine: Results from a Randomized Prospective Multi-Center Trial
Joachim Sieper¹, Joachim Listing², Denis Poddubnyy¹, In-Ho Song^1,3, Kay-Geert Hermann¹, Johanna Callhoff², Jürgen Braun⁴ and Martin Rudwaleit^1,5, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²German Rheumatism Research Centre, Berlin, Germany, ³Abbvie, Chicago, IL, ⁴Rheumazentrum Ruhrgebiet, Herne, Germany, ⁵Klinikum Bielefeld, Bielefeld, Germany
Background/Purpose: Previously it was shown that non-steroidal antiinflammatory drugs (NSAIDs) given continuously reduce radiographic progression compared to an on demand therapy over 2 years in…
Abstract Number: 1730 • 2015 ACR/ARHP Annual Meeting
Good Control of Inflammation Counterbalances a Negative Impact of Radiographic Spinal Progression on Functional Status and Spinal Mobility in Patients with Ankylosing Spondylitis Treated with TNF Inhibitors
Denis Poddubnyy¹, Aleksandra Fedorova¹, Joachim Listing², Hildrun Haibel¹, Xenofon Baraliakos³, Jürgen Braun³ and Joachim Sieper¹, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²German Rheumatism Research Centre, Berlin, Germany, ³Rheumazentrum Ruhrgebiet, Herne, Germany
Background/Purpose: Impaired function and spinal mobility in patients with ankylosing spondylitis (AS) can be caused by both spinal inflammation and new bone formation. Anti-TNF therapy…
Abstract Number: 2811 • 2015 ACR/ARHP Annual Meeting
Higher Serum Level of Leptin Protects from Radiographic Spinal Progression in Patients with Ankylosing Spondylitis
Agnes Hartl¹, Kay-Geert Hermann¹, In-Ho Song^1,2, Joachim Listing³, Martin Rudwaleit^1,4, Joachim Sieper¹ and Denis Poddubnyy¹, ¹Charité Universitätsmedizin Berlin, Berlin, Germany, ²Abbvie, Chicago, IL, ³German Rheumatism Research Centre, Berlin, Germany, ⁴Klinikum Bielefeld, Bielefeld, Germany
Background/Purpose: Fat tissue synthesizes and releases a series of biologically active substances (adipokines), which are involved in bone metabolism through effects on bone formation and…
Abstract Number: 2816 • 2015 ACR/ARHP Annual Meeting
Is the Gender Difference in As Linked to IL-23?
Johannes Nossent¹ and Gunnstein Bakland^2,3, ¹Medicine, University of Western Australia, WA, Australia, ²Dept. of Rheumatology, University Hospital Northern Norway, Tromsø, Norway, ³University of Tromsø, The Arctic University of Norway, Tromsø, Norway
Background/Purpose: Ankylosing Spondylitis (AS) has traditionally been portrayed as a disease where male patients outnumber female patients by a factor 3 to 4. It has…
Abstract Number: 556 • 2014 ACR/ARHP Annual Meeting
Defining Flare in Spondyloarthritis : Thresholds of Disease Activity Variations
Marie Godfrin-Valnet¹, Marc Puyraveau² and Daniel Wendling³, ¹Rheumatology, CHRU, Besançon, France, ²Investigation Center, CHRU, Besançon, France, ³Service de Rhumatologie, CHU J Minjoz, Besancon, France
Background/Purpose: Spondyloarthritis (SpA) activity varies with time and treatment, but to date no clear definition of a flare of the disease is available. The aim…
Abstract Number: 551 • 2014 ACR/ARHP Annual Meeting
Predictors Associated with Rheumatologist Referral Time in Patients with Ankylosing Spondylitis
Atul A. Deodhar¹, Manish Mittal², Patrick Reilly², Yanjun Bao², Shivaji Manthena², Jaclyn K. Anderson² and Avani D. Joshi², ¹Oregon Health and Sciences University, Portland, OR, ²AbbVie Inc., North Chicago, IL
Background/Purpose: Average delay between symptom onset and diagnosis of ankylosing spondylitis (AS) has been reported as 8–12.8 years1,2. This study assessed delay in AS diagnosis…
Abstract Number: 40 • 2014 ACR/ARHP Annual Meeting
Prevalence of Spondyloarthritis (ASAS Criteria) in First-Degree Relatives of Patients with Ankylosing Spondylitis
Raúl Menor Almagro¹, Carmen Ordas², Carlos Montilla³, Jose Luis Alvarez-Vega⁴, Íñigo Hernández-Rodríguez⁵, Montserrat Corteguera⁶, Santiago MuÑoz Fernandez⁷, Claudia Urrego⁸, Rafael Ariza-Ariza⁹, Mireia Moreno¹⁰, Xavier Juanola¹¹, Maria Isabel Tévar¹², Eduardo Collantes- Estevez¹³, Juan Mulero- Mendoza¹⁴ and Ana Ruiz-Zorrilla¹⁵, ¹Rheumatology, Hospital de Jerez, Jerez de la Frontera, Spain, ²Hospital de Cabueñes, Gijón, Spain, ³Rheumatology, Hospital Clínico Universitario de Salamanca, Salamanca, Spain, ⁴H. de Salamanca, Salamanca, Spain, ⁵Rheumatology, University Hospital Complex of Vigo, Vigo, Spain, ⁶Hospital Nª Sª Sonsoles, Avila, Spain, ⁷Sección de Reumatología, Hospital Universitario Infanta Sofía, San Sebastián de los Reyes, Madrid, Spain, ⁸Hospital G. Segovia, Segovia, Spain, ⁹Rheumatology, University Hospital Virgen Macarena, Sevilla, Spain, ¹⁰Rheumatology, Hospital Universitari Parc Taulí, Sabadell, Spain, ¹¹Rheumatology, University Hospital Bellvitge, Barcelona, Spain, ¹²Hospital Vega Baja, Orihuela, Alicante, Spain, ¹³Hospital Reina Sofía, Córdoba, Spain, ¹⁴Hospital Puerta de Hierro, Madrid, Spain, ¹⁵Abbvie, Madrid, Spain
Background/Purpose: Spondyloarthritis (SpA), a group of inflammatory diseases which exhibit similar genetic background, clinical features and symptoms1, has an estimated prevalence of 0.5-1%2 in Spain.…
Abstract Number: 2473 • 2013 ACR/ARHP Annual Meeting
Comparison Of The Two Subtypes Of Axial Spondyloarthritis Patients Fulfilling The Imaging Arm Based On Radiographic and MRI Findings
Dilek Solmaz, Servet Akar, Ismail Sari, Pinar Cetin, Fatos Onen and Nurullah Akkoc, Rheumatology, Dokuz Eylul University School of Medicine, Izmir, Turkey
Background/Purpose: New Axial Spondyloarthritis Classification Criteria include an imaging arm and a clinical arm. The imaging arm includes radiographic ax-SpA patients who have radiographic sacroilitis…
Abstract Number: 2472 • 2013 ACR/ARHP Annual Meeting
Disease Burden Is Similar Between Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis and Independent Of Gender Influences
Salih Ozgocmen¹, Erkan Kilic², Gamze Kilic² and Ozgur Akgul², ¹Division of Rheumatology, Dept.PRM, Erciyes University, Faculty of Medicine, Kayseri, Turkey, ²Division of Rheumatology, Dept. PRM, Erciyes University, Faculty of Medicine, Kayseri, Turkey
Disease Burden is Similar between Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis and Independent of Gender Influences Background/Purpose: Axial spondyloarthritis (SpA) covers both ankylosing spondylitis (AS)…
Abstract Number: 2437 • 2013 ACR/ARHP Annual Meeting
Prevalence Of Axial Spondyloarthritis In The United States Among Patients With Chronic Back Pain and Other Spondyloarthritis-Related Features
Atul A. Deodhar¹, Philip J. Mease², Jeffrey R. Curtis³, Piyalal M. Karunaratne⁴, Kailash Malhotra⁴ and Aileen L. Pangan⁴, ¹Oregon Health & Science University, Portland, OR, ²University of Washington and Swedish Medical Center, Seattle, WA, ³University of Alabama at Birmingham, Birmingham, AL, ⁴AbbVie Inc., North Chicago, IL
Background/Purpose: The age-adjusted prevalence of spondyloarthritis (SpA) has been estimated to be 0.9-1.4% of the US population using the Amor and ESSG criteria. The objective…

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