Abstracts tagged "Ankylosing spondylitis (AS) and polymorphism"

Abstract Number: 972 • ACR/ARHP Annual Meeting 2012
Associations of Genetic Polymorphisms of Microrna-146a and Its Target Interleukin-1-Receptor-Associated Kinase 1 with Ankylosing Spondylitis
Chun-Huang Huang¹, Jia-Yan Zhan², Kai-Jieh Yeo³, James C. Wei⁴, Chih-Shien Chuang² and Ruey-Hong Wong², ¹Institute of Medicine, Chung Shan Medical University, Taichung, Taiwan, ²Department of Public Health, Chung Shan Medical University, Taichung, Taiwan, ³Division of Allergy, Immunology and Rheumatology, Chung Shan Med Univ Hospital, Taichung, Taiwan, ⁴Allergy/Immunology/Rheumatolog, Chung Shan Med Univ Hospital, Taichung, Taiwan
Background/Purpose: Tumor necrosis factor-α (TNF-α) and interleukin-1 (IL-1) were important mediators of inflammation response in the development of ankylosing spondylitis (AS). Especially, microRNA (miR)-146a targets…