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Abstracts tagged "Ankylosing spondylitis (AS) and microbiome"

  • Abstract Number: 2079 • 2018 ACR/ARHP Annual Meeting

    Dysbiosis of Gut Microbiomes in Ankylosing Spondylitis

    Chen Zhou1, Xuan Zhang2 and Xiao Xinyue1, 1Peking Union Medical College Hospital, Beijing, China, 2Rheumatology, Peking Union Medical College Hospital, Beijing, China

    Background/Purpose: Ankylosing spondylitis (AS) is a common chronic, systemic, inflammatory disease. Gut microbiome has been reported to play an important role in the homeostasis of…
  • Abstract Number: 3166 • 2016 ACR/ARHP Annual Meeting

    HLA-B27 and Ankylosing Spondylitis Have Shared Effects on the Gut Microbiome

    Mary-Ellen Costello1, Mark Asquith2, Kim-Anh Lê Cao3, Tammy Martin4, Sarah Diamond2, Michelle Beaumont5, Timothy D. Spector5, James T. Rosenbaum2 and Matthew A. Brown1, 1Translational Research Institute, Translational Genomics Group, Institute of Health and Biomedical Innovation, Queensland University of Technology, Brisbane, Australia, 2Oregon Health & Science University, Portland, OR, 3Translational Research Instiute, The University of Queensland Diamantina Institute, Brisbane, Australia, 4Ophthalmology, Oregon Health & Science Univ, Portland, OR, 5Dept of Twin Research and Genetic Epidemiology, King's College London, London, United Kingdom

    Background/Purpose: Evidence for a discrete intestinal microbiome signature in the terminal ileum (TI) of ankylosing spondylitis (AS) patients, compared to healthy controls, has recently been…
  • Abstract Number: 2497 • 2013 ACR/ARHP Annual Meeting

    Evidence Of a Microbial Signature In The Intestinal Microbiome In Ankylosing Spondylitis

    Mary-Ellen Costello1, Francesco Ciccia2, Brooke Gardiner3, Mhairi Marshall3, Dana Willner4, Tony Kenna3, Giovanni Triolo2 and Matthew A. Brown3, 1Human Genetics Group, University of Queensland Diamantina Institute, Brisbane, Australia, 2Rheumatology Unit, University of Palermo, Palermo, Italy, 3University of Queensland Diamantina Institute, Brisbane, Australia, 4Australian Centre for Ecogenomics, School of Chemistry and Molecular Biosciences, University of Queensland, Brisbane, Australia

    Background/Purpose: Ankylosing spondylitis (AS) occurs in genetically predisposed individuals exposed to an unknown but likely ubiquitous environmental trigger.  In both AS and Crohn’s disease (CD)…
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