Abstracts tagged "Ankylosing spondylitis (AS) and infliximab"

Abstract Number: 1550 • 2013 ACR/ARHP Annual Meeting
Validation Of The Ankylosing Spondylitis Disease Activity Score and Effectiveness Of Infliximab In The Treatment Of Ankylosing Spondylitis Over 4 Years: The Canadian Experience
Proton Rahman¹, Denis Choquette², Majed M. Khraishi³, William G. Bensen⁴, Saeed A. Shaikh⁵, Dalton E. Sholter⁶, Maqbool K. Sheriff⁷, Emmanouil Rampakakis⁸, John S. Sampalis⁸, Francois Nantel⁹, Susan M. Otawa¹⁰, Allen J. Lehman¹⁰ and May Shawi¹¹, ¹Faculty of Medicine, Memorial University of Newfoundland, St. John's, NF, Canada, ²Rheumatology, Institut de rhumatologie de Montréal (IRM), Montréal, QC, Canada, ³Nexus Clinical Research, St John's, NF, Canada, ⁴Department of Medicine, Division of Rheumatology, Clinical Professor, McMaster University, Hamilton, ON, Canada, ⁵Medicine, McMaster University, St Catharines, ON, Canada, ⁶Rheumatology Associates, Edmonton, AB, Canada, ⁷Nanaimo Regional General Hospital, Nanaimo, BC, Canada, ⁸JSS Medical Research, Montreal, QC, Canada, ⁹Janssen Inc., Toronto, ON, Canada, ¹⁰Medical Affairs, Janssen Inc., Toronto, ON, Canada, ¹¹Medical Affairs, Janssen Canada Inc, Toronto, ON, Canada
Background/Purpose: The efficacy of anti-TNF in the management of Ankylosing Spondylitis (AS) has been demonstrated in numerous controlled clinical trials. The objective of this study…
Abstract Number: 780 • 2012 ACR/ARHP Annual Meeting
The Relationship of Inflammation, Fatty Degeneration and the Effect of Long-Term TNF-Blocker Treatment On the Development of New Bone Formation in Patients with Ankylosing Spondylitis
Xenofon Baraliakos¹, Frank Heldmann², Joachim Listing³, Johanna Callhoff³, Jürgen Braun² and EASIC⁴, ¹Rheumatology, Rheumazentrum Ruhrgebiet, Herne, Germany, ²Rheumazentrum Ruhrgebiet, Herne, Germany, ³German Rheumatism Research Center, Berlin, Germany, ⁴Herne, Germany
Background/Purpose: Clinical trial results suggest that new bone formation is neither inhibited nor augmented by anti-TNF agents in ankylosing spondylitis (AS). Recently, a potential role…

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