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Abstracts tagged "ankylosing spondylitis (AS) and cartilage"

  • Abstract Number: 526 • 2013 ACR/ARHP Annual Meeting

    Endochondral Bone Formation and Advanced Enthesitis Are Key Features Of Proteoglycan Induced Spondylitis Mouse Model Of Ankylosing Spondylitis

    Gethin P Thomas1, Hsu-Wen Tseng2, Allison Pettit3,4, Tibor T. Glant5, Allan McRae2 and Matthew A. Brown6, 1Translational Reserch Institute, University of Queensland Diamantina Institute, Woolloongabba, Australia, 2University of Queensland Diamantina Institute, Woolloongabba, Australia, 3Mater Research, Woolloongabba, Australia, 4University of Queensland Centre for Clinical Research, Herston, Australia, 5Orthopedic Surgery, Rush University Medical Center, Chicago, IL, 6University of Queensland Diamantina Institute, Brisbane, Australia

    Background/Purpose: Transition from an initial inflammatory phase to the disabling osteoproliferative phase in ankylosing spondylitis (AS) is very poorly understood. Elucidation of the mechanisms underlying…
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