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Abstracts tagged "ankylosing spondylitis (AS) and axial spondyloarthritis"

  • Abstract Number: 599 • 2019 ACR/ARP Annual Meeting

    Muscle Physical Properties in Young Adult Axial Spondyloarthritis Patients, the MyoSpA Study

    Fernando Pimentel-Santos1, Agna Neto 2, Lúcia Domingues 3, Atlas Sardoo 3, Santiago Rodrigues-Manica 1, Rita Pinheiro Torres 4, Carolina Crespo 5, Alexandre Sepriano 6, Sofia Ramiro 7, Kalyani Nair 8, Júlia Costa 9, Patrícia Gomes-Alves 10, Alfonse Masi 11 and Jaime Branco 1, 1CEDOC, NOVA-Medical School | Hospital Egas Moniz, CHLO, Lisbon, Lisbon, Portugal, 2Rheumatology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental; CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon; Hospital Central do Funchal, Madeira., Lisbon, Portugal, 3CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon, Lisbon, Portugal, 4Rheumatology Department, Hospital de Egas Moniz, Centro Hospitalar de Lisboa Ocidental; CEDOC, NOVA Medical School, Faculdade de Ciências Médicas, Lisbon., Lisbon, Portugal, 5CEDOC, NOVA Medical School, Universidade Nova de Lisboa, Lisboa, Portugal, Lisbon, Portugal, 6Leiden University Medical Center, Leiden, Netherlands, 7Leiden University Medical Center and Zuyderland Medical Centre, Leiden, Netherlands, 8Bradley University and University of Illinois College of Medicine at Peoria, Illinois, USA, Peoria, IL, 9Instituto de Tecnologia Química e BiológicaAntónio Xavier, Universidade NOVA de Lisboa, Av. República, 2780-157 Oeiras, Portugal, Oeiras, Portugal, 10Instituto de Tecnologia Química e Biológica António Xavier, Universidade NOVA de Lisboa, Oeiras, Portugal, Oeiras, Portugal, 11University of Illinois College of Medicine at Peoria and Bradley University, Peoria Illinois, USA, Peoria, IL

    Background/Purpose: An important mechanism regarding axial spondyloarthritis (axSpA) susceptibility and progression is the biomechanical concept, suspected from axial myofascial hypertonicity and stiffness in ankylosing spondylitis…
  • Abstract Number: L12 • 2018 ACR/ARHP Annual Meeting

    Efficacy and Safety of Ixekizumab in the Treatment of Radiographic Axial Spondyloarthritis: 16 Week Results of a Phase 3 Randomized, Double-Blind, Placebo-Controlled Trial in Patients with Prior Inadequate Response or Intolerance to 1 or 2 Tumor Necrosis Factor Inhibitors

    Atul A. Deodhar1, Denis Poddubnyy2, Cesar Pacheco-Tena3, Carlo Salvarani4, Eric Lespessailles5, Proton Rahman6, Pentti Järvinen7, Juan Sanchez-Burson8, Karl Gaffney9, Eun Bong Lee10, Eswar Krishnan11, Silvia Santisteban11, Xiaoqi Li11, Fangyi Zhao11, Hilde Carlier11 and John D. Reveille12, 1Oregon Health & Science University, Portland, Portland, OR, 2Rheumatology, Campus Benjamin Franklin Charité – Universitätsmedizin, Germany and German Rheumatism Research Centre, Berlin, Germany, Berlin, Germany, 3Facultad de Medicina, Universidad Autónoma de Chihuahua, Chihuahua, Mexico, 4Azienda USL-IRCCS di Reggio Emilia and Universita’ di Modena e Reggio Emilia, Reggio Emilia, Italy, 5Rheumatology, CHR Orléans and University of Orléans, Orléans, France, 6Medicine, Memorial University, St John's, NF, Canada, 7Rheumatology, Kiljava Medical Research, Hyvinkää, Finland, 8Hospital Infanta Luisa, Sevilla, Spain, 9Rheumatology, Norfolk and Norwich University Hospital NHS Foundation Trust and Norwich Medical School, University of East Anglia, Norwich, United Kingdom, 10Division of Rheumatology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea, Republic of (South), 11Eli Lilly and Company, Indianapolis, IN, 12Rheumatology, McGovern Medical School at the University of Texas Health Science Center at Houston, USA, Houston, TX

    Background/Purpose: TNF inhibitors (TNFi) are recommended for patients with axial SpA (axSpA) who do not respond to or tolerate NSAIDs.  Some patients are inadequate responders…
  • Abstract Number: 1627 • 2018 ACR/ARHP Annual Meeting

    Assessment of Myocardial Dysfunction Using Speckle Tracking Echocardiography in Patients with Ankylosing Spondylitis and Nonradiographic Axial Spondyloarthritis

    Volkan Emren1, Onay Gercik2, Emre Ozdemir3, Dilek Solmaz2, Nihan Eren3, Mehmet Tokac3, Gökhan Kabadayı2, Sercan Gucenmez2 and Servet Akar4, 1Faculty Of Medicine, Department of Cardiology, Izmir Katip Celebi University, Izmir, Turkey, 2Rheumatology, Izmir Katip Celebi University, Faculty of Medicine, Izmir, Turkey, 3Faculty Of Medicine, Department Of Cardiology, Izmir Katip Celebi University, Izmir, Turkey, 4Faculty of Medicine, Department of Rheumatology, Izmir Katip Celebi University, Izmir, Turkey

    Background/Purpose: Axial spondyloarthritis (axSpA) is a chronic inflammatory disease that mainly affects axial skeleton. Although some differences like sex and objective signs of inflammation were…
  • Abstract Number: 2887 • 2018 ACR/ARHP Annual Meeting

    Chronic Pain and Assessment of Pain Sensitivity in Patients with Established Axial Spondyloarthritis – a Cross-Sectional Study

    Elisabeth Mogard1, Tor Olofsson2, Stefan Bergman3, Ann Bremander4, Lars Erik Kristensen5, Jack Kvistgaard Olsen6, Johan K Wallman7 and Elisabet Lindqvist8, 1Department of Clinical Sciences Lund, Section of Rheumatology, Lund University, Faculty of Medicine and Skåne University Hospital, Lund, Sweden, 2Lund University, Department of Clinical Sciences Lund, Rheumatology, Lund, Sweden, Lund, Sweden, 3University of Gothenburg, Gothenburg, Sweden, 4Spenshult Research and Development Center, Halmstad, Sweden, 5Department of Rheumatology, Copenhagen University Hospital, Frederiksberg and Bispebjerg, The Parker Institute, Copenhagen, Denmark, 6Department of Rheumatology, Copenhagen University Hospital, Fredriksberg and Bispebjerg, The Parker Institute, Copenhagen, Denmark, 7Department of Clincial Sciences Lund, Rheumatology, Lund University, Lund, Sweden, 8Department of Clinical Sciences Lund,Section of Rheumatology, Lund University, Faculty of Medicine and Skåne University Hospital, Lund, Sweden

    Background/Purpose: Pain remains a common and debilitating symptom in arthritis, despite good options to treat inflammation. In axial spondyloarthritis (axSpA), data on chronic pain remain…
  • Abstract Number: 1509 • 2017 ACR/ARHP Annual Meeting

    Similarities and Differences between Non-Radiographic and Radiographic Axial Spondyloarthritis

    Denis Poddubnyy1, Robert D Inman2, Joachim Sieper1, Servet Akar3, Santiago Muñoz-Fernández4 and Maja Hojnik5, 1Charité Universitätsmedizin Berlin, Berlin, Germany, 2Toronto Western Hospital, Toronto, ON, Canada, 3Rheumatology, Izmir Katip Celebi University, School of Medicine, Rheumatology, Izmir, Turkey, 4Hospital Universitario Infanta Sofía, Universidad Europea, Mardid, Spain, 5AbbVie, Ljubljana, Slovenia

    Background/Purpose: Differences between non-radiographic and radiographic axial spondyloarthritis (axSpA) – such as a higher prevalence of females and lower level of acute phase reactants in…
  • Abstract Number: 1522 • 2017 ACR/ARHP Annual Meeting

    Patients with Ankylosing Spondylitis Had Better Adalimumab Survival Than Patients with Non-Radiographic Axial Spondyloarthritis

    Alper Sari1, Berkan Armagan1, Abdulsamet Erden2, Levent Kilic1,2, Omer Karadag2,3, Ali Akdogan1, Umut Kalyoncu2 and Ihsan Ertenli2, 1Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 2Department of Internal Medicine, Divison of Rheumatology, Hacettepe University Faculty of Medicine, Ankara, Turkey, 3Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, Cambridge, United Kingdom

    Patients with ankylosing spondylitis had better adalimumab survival than patients with non-radiographic axial spondyloarthritis Background/Purpose: Drug survival rate is generally accepted as a reliable indicator of…
  • Abstract Number: 2719 • 2016 ACR/ARHP Annual Meeting

    Discriminating Value of Calprotectin in Disease Activity and Progression of Non-Radiographic Axial Spondyloarthritis and Ankylosing Spondylitis

    Jinxian Huang1, Zhihua Yin2, Guoxiang Song3, Shengjin Cui4, Jinzhao Jiang4 and Lijun Zhang4, 1Rheumatology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, China, 2Rheumatology, The Fourth People’s Hospital of Shenzhen, Shenzhen, China, 3The Third People’s Hospital of Shenzhen, Shenzhen, China, 4The University of Hong Kong-Shenzhen Hospital, Shenzhen, China

    Background/Purpose:  Due to the limitation of early diagnosis of ankylosing spondylitis (AS), updated criteria in recent years introduced the concept of axial spondyloarthritis (axSpA) and…
  • Abstract Number: 1728 • 2015 ACR/ARHP Annual Meeting

    Diffusion Weighted Imaging Is a Sensitive and Specific MRI Protocol for the Diagnosis and Assessment of Disease Severity in Ankylosing Spondylitis

    Linda A. Bradbury1, Kelly A. Hollis2, Benoit Gautier2, Sateesh Shankaranarayana3, Philip Robinson4, Nivene Saad3, Kim-Anh Lê Cao2 and Matthew A. Brown1, 1The University of Queensland Diamantina Institute, Brisbane, Australia, 2University of Queensland Diamantina Institute, Brisbane, Australia, 3Princess Alexandra Hospital, Brisbane, Australia, 4Human Genetics Group, University of Queensland Diamantina Insititute, Brisbane, Australia

    Background/Purpose: Diffusion weighted imaging (DWI) is an MRI protocol which assesses the random Brownian motion of water molecules in the tissue imaged; this motion is…
  • Abstract Number: 1713 • 2015 ACR/ARHP Annual Meeting

    Fat Metaplasia on Sacroiliac Joint Magnetic Resonance Imaging at Baseline Is Associated with Spinal Radiographic Progression in Patients with Axial Spondyloarthritis

    Kwi Young Kang1, In Je Kim2, Yeon Sik Hong3, Sung-Hwan Park4 and Ji Hyeon Ju5, 1#505, Banpo-dong, Seocho-gu, Division of Rheumatology, Department of Internal Medicine, Catholic University of Korea, Seoul, South Korea, 2Division of Rheumatology, Department of Internal Medicine, Ewha Womans University School of Medicine, Seoul, South Korea, 3catholic University of Korea, Incheon, South Korea, 4Kangnam St Mary's Hospital, Seoul, South Korea, 5Division of Rheumatology, Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, South Korea

    Background/Purpose: To study the relationship between inflammatory and structural lesions in the sacroiliac joints (SIJs) on MRI and spinal progression observed on conventional radiographs in…
  • Abstract Number: 553 • 2014 ACR/ARHP Annual Meeting

    Comparison of Baseline Extra-Articular Manifestations, Comorbidities, and Long-Term Safety in Patients Treated with Adalimumab for Ankylosing Spondylitis and Non-Radiographic Axial Spondyloarthritis

    Joachim Sieper1, Désirée van der Heijde2, Nupun A. Varothai3 and Jaclyn K. Anderson3, 1Charité Universitätsmedizin Berlin, Berlin, Germany, 2Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, 3AbbVie Inc., North Chicago, IL

    Background/Purpose: To compare 1) extra-articular manifestations, 2) baseline comorbidities, and 3) adverse event (AE) rates with long-term adalimumab (ADA) therapy in patients (pts) treated in…
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