Abstracts tagged "Animal models and osteoclastogenesis"

Abstract Number: 1299 • 2013 ACR/ARHP Annual Meeting
PTEN Controls Osteoclastogenesis and Inflammatory Bone Destruction In a TNF-Driven Model Of Arthritis
Stephan Blueml¹, Gernot Schabbauer², Antonia Puchner³, Victoria Saferding⁴, Emine Sahin², Julia Brunner⁵, Tobias Lohmeyer⁵, Josef S. Smolen⁶ and Kurt Redlich⁷, ¹Division of Rheumatology, Medical University of Vienna, Vienna, Austria, ²Vascular Biology and Thrombosis research, Medical University Vienna, Vienna, Austria, ³Department of Rheumatology, Medical University of Vienna, Vienna, Austria, ⁴Rheumatology, Medical University of Vienna, Vienna, Austria, ⁵Medical University Vienna, Vienna, Austria, ⁶Medical University of Vienna, Vienna, Austria, ⁷Department of Internal Medicine III, Division of Rheumatology, Medical University of Vienna, Vienna, Austria
Background/Purpose: Local bone destruction in inflammatory arthritides in humans such as rheumatoid arthritis is a serious health burden and the major cause of disability and…

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