Abstracts tagged "animal models and non-human primates (NHPs)"

Abstract Number: 2821 • 2013 ACR/ARHP Annual Meeting
Evaluation Of Selective Manipulation Of The CD28 Co-Stimulation Pathway In The Rhesus Monkey Model Of Collagen-Induced Arthritis
Michel P.M. Vierboom¹, Elia Breedveld¹, Bert 't Hart¹, Flora Coulon² and Bernard Vanhove³, ¹Department of Immunobiology, Biomedical Primate Research Centre, Rijswijk, Netherlands, ²UMR-S 1064, Institut National de la Santé et de la Recherche Médicale, Nantes, France, ³Institut de Transplantation - Urologie - Néphrologie, INSERM UMR-S 1064, Nantes, France
Background/Purpose: T-cells are important in the pathogenesis of rheumatoid arthritis (RA). T-cell activation depends on at least two signals. Next to the first signal that…

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Abstracts tagged "animal models and non-human primates (NHPs)"

Evaluation Of Selective Manipulation Of The CD28 Co-Stimulation Pathway In The Rhesus Monkey Model Of Collagen-Induced Arthritis