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Abstracts tagged "animal models and inflammatory arthritis"

  • Abstract Number: 1297 • ACR/ARHP Annual Meeting 2013

    Human IL-1alpha Conditional Transgenic Mice Mimic Autoinflammatory Syndromes In Human

    Hiroya Kanagawa1, Yasuo Niki2, Yoshiaki Toyama3 and Takeshi Miyamoto4, 1Department of Orthopaedic Surgery, Keio University, Shinjuku-ku, Tokyo, Japan, 2Orthopaedic Surgery, Department of Orthopaedic Surgery, Keio University, Tokyo, Japan, 3Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan, 4Department of Orthopaedic Surgery, Keio University, Shinjuku-ku,Tokyo, Japan

    Background/Purpose: Recently, IL-1 is implicated in the pathogenesis of autoinflammatory syndrome, which characterized by rash, fever, systemic polyarthritis and neurological comorbidity. Recently, IL-1 becomes noticed…

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