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Abstracts tagged "Angiogenesis and signal transduction"

  • Abstract Number: 2802 • ACR/ARHP Annual Meeting 2014

    Non-Canonical NF-Kappab Signaling Promotes Angiogenesis in a Novel 3D Spheroid Model of Rheumatoid Arthritis Synovial Inflammation

    Chrissta X. Maracle1, Boy Helder2, Ae-Ri Noort1, Corine van der Horst3 and Sander W. Tas1, 1Department of Clinical Immunology & Rheumatology and Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 2Department of Clinical Immunology and Rheumatology and Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 3Arthrogen BV, Amsterdam, Netherlands

    Background/Purpose: Angiogenesis is regarded as a switch from acute to chronic inflammation and thus plays a crucial role in rheumatoid arthritis disease progression. This process…
  • Abstract Number: 945 • ACR/ARHP Annual Meeting 2013

    Non-Canonical NF-Kappa B Signaling Enhances Angiogenesis In a Novel 3D Spheroid Model Of Rheumatoid Arthritis Synovial Inflammation

    Chrissta X. Maracle1, Ae-Ri Noort2, Katinka P.M. van Zoest2 and Sander W. Tas1, 1Department of Clinical Immunology & Rheumatology and Department of Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands, 2Department of Clinical Immunology & Rheumatology and Laboratory for Experimental Immunology, Academic Medical Center, University of Amsterdam, Amsterdam, Netherlands

    Background/Purpose: Angiogenesis plays a crucial role in rheumatoid arthritis (RA) synovitis and is regarded as a switch from acute to chronic inflammation. Previously, we have…

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