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Abstracts tagged "anakinra and histopathologic"

  • Abstract Number: 922 • ACR/ARHP Annual Meeting 2018

    Anakinra Treatment Prevents Myocardial Mechanical Dysfunction and Inhibits Histologic Evidence of Myocardial Inflammation in the Mouse Model of Kawasaki Disease

    Mark Gorelik1,2, Youngho Lee3, Masanori Abe4, Thomas Andrews5, Jean Patterson1, Magali Noval Rivas4, Gregory Aune5 and Moshe Arditi4, 1Immunology and Virology, Texas Biomedical Research Institute, San Antonio, TX, 2Pediatrics, Baylor College of Medicine, Houston, TX, 3Department of Cell Biology, Hospital for Sick Children, Toronto, ON, Canada, 4Pediatrics, Cedars Sinai, Beverly Hills, CA, 5Greehey Children's Cancer Research Institute, University of Texas Health Science Center at San Antonio, San Antonio, TX

    Background/Purpose: Kawasaki disease (KD) is an acute, febrile illness of childhood with sequelae of coronary artery aneurysms and cardiac fibrosis, and is the most common…

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