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Abstracts tagged "amino acid and plasmablast differentiation"

  • Abstract Number: 2814 • 2019 ACR/ARP Annual Meeting

    Methionine Commits Immunometabolism and Epigenetic Regulation of BACH2 Loci in B Cells, Resulting in Biases Toward Plasmablast Differentiation in the Pathogenesis of SLE

    Mingzeng Zhang1, Shigeru Iwata 1, Maiko Hajime 1, Naoaki Ohkubo 1, Yasuyuki Todoroki 2, Hiroko Miyata 2, Jie Fan 2, Shingo Nakayamada 1, Kaoru Yamagata 1 and Yoshiya Tanaka 3, 1The First Department of Internal Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan, Kitakyushu, Japan, 2The First Department of Internal Medicine, University of Occupational & Environmental Health Kitakyushu, Japan, Kitakyushu, Japan, 3University of Occupational and Environmental Health Japan, Kitakyushu, Japan

    Background/Purpose: Amino acids play an important role in various metabolic processes. However, the role of amino acid metabolism in the regulation of human B cell…
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ACR Pediatric Rheumatology Symposium 2020

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