Abstracts tagged "Aging and autophagy"

Abstract Number: 1992 • 2019 ACR/ARP Annual Meeting
Adenosine A2A Receptor (A2AR) Stimulation Mitigates Mitochondrial Inflammaging, Enhances Mitochondrial Metabolism and Reduces Reactive Oxygen Species-Mediated Mitochondrial Injury In Vitro and In Vivo in Osteoarthritis
Cristina Castro¹, Carmen Corciulo ², Maria Solecio ³, Benjamin Friedman ⁴, Fengxia Liang ⁵, Zhi Li ⁶, Samson Jacob ⁷, David Fenyo ⁸, Evgeny Pavlov ⁹ and Bruce Cronstein ⁴, ¹Immunology and Inflammation Training Program at Skirball Institute of Graduate Biomolecular Sciences, New York University School of Medicine (NYUSoM), NYC, ²Division of Translational Medicine NYUSoM, NYC, ³NYU College of Dentistry, NYC, ⁴Department of Medicine, Division of Rheumatology NYUSoM, NYC, ⁵Department of Cell Biology, NYU Langone Health, NYC, ⁶Institute for Systems Genetics, Department of Biochemistry and Molecular Pharmacology, NYU Langone Helalth, NYC, ⁷Institute for Systems Genetics, NYU Langone Health, NYC, ⁸Institute for Systems Genetics, Department of Biochemistry and Molecular Pharmacology, NYC, ⁹Basic Science and Craniofacial Biology, NYU College of Dentistry, NYC
Background/Purpose: Osteoarthritis (OA) is the most common form of arthritis, affecting nearly 10% of the US population and one of the contributing factors in OA…

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