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Abstracts tagged "age-associated B cells and Cholesterol Homeostasis"

  • Abstract Number: 957 • 2019 ACR/ARP Annual Meeting

    Alterations in Cholesterol Homeostasis Regulate Autoimmunity/Age-associated B Cells

    Zhu Chen1, Michela Manni 1, Danny Flores-Castro 1, Tania Pannellini 1 and Alessandra Pernis 2, 1Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, 21.Autoimmunity and Inflammation Program, Hospital for Special Surgery. 2.David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery. 3.Department of Medicine, Weill Cornell Medical College, Cornell University, New York

    Background/Purpose: Age-associated B cells (ABCs) are a novel B cell subset, which expands with age in non-autoimmune mice but accumulates prematurely in autoimmune-prone strains. ABCs…
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