ACR Meeting Abstracts

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Abstracts tagged "Adverse events"

  • Abstract Number: 1403 • 2015 ACR/ARHP Annual Meeting

    Immune Related Adverse Events Associated with Immune Checkpoint Inhibitors in Cancer Patients: A Systematic Review of Case Reports

    Noha Abdel-Wahab1,2 and Maria E. Suarez-Almazor3, 1Rheumatology & Rehabilitation Department, Assiut University Hospital, Egypt, Assiut, Egypt, 2The Department of General Internal Medicine, The University of Texas, MD Anderson Cancer Center, USA, Houston, TX, 3General Internal Medicine, The University of Texas, MD Anderson Cancer Center, Houston, TX

    Background/Purpose: Background: The recent discovery of the immune checkpoint blockade that targets the regulatory pathways in T cells to enhance antitumor immune responses has led…
  • Abstract Number: 1488 • 2015 ACR/ARHP Annual Meeting

    Following the American College of Rheumatology Quality Guidelines Can Enhance the Safety of Rheumatoid Arthritis Patients Treated with Disease Modifying Drugs

    Delfina Bur1 and Humeira M. Badsha2, 1Dr. Humeira Badsha Medical Clinic, Dubai, United Arab Emirates, 2Rheumatology, Dr Humeira Badsha Medical Center, Dubai, United Arab Emirates

    Background/Purpose:  Adverse events (AEs) and serious adverse events (SAEs) from disease modifying drugs (DMARDs) for Rheumatoid Arthritis (RA) can result in significant morbidity and even…
  • Abstract Number: 1538 • 2015 ACR/ARHP Annual Meeting

    Clinical Analysis of 30 Rheumatoid Arthritis Patients Complicated with Malignant Lymphoma, Especially Methotrexate-Related Lymphoproliferative Disorder

    Takuma Tsuzuki Wada1, Yuji Akiyama1 and Toshihide Mimura2, 1Department of Rheumatology & Applied Immunology, Faculty of Medicine, Saitama Medical University, Iruma, Japan, 2Department of Rheumatology and Applied Immunology, Faculty of Medicine, Saitama Medical University, Saitama, Japan

    Background/Purpose: Recently, methotrexate (MTX) has been considered as the anchor drug in the treatment of rheumatoid arthritis (RA). However, it has been reported that MTX…
  • Abstract Number: 1631 • 2015 ACR/ARHP Annual Meeting

    Adverse Events to Biologic Agents in Elderly Patients with Rheumatoid Arthritis: Cohort with 13 Years of Follow-up

    Zulema Rosales1,2, Leticia Leon1, Alejandro Gomez-Gomez2, Lucía Arietti2, Esperanza Pato Cour2, José Luis Fernández Rueda1, Juan A Jover2 and Lydia Abasolo1, 1Instituto de Investigación Sanitaria San Carlos (IdISSC), Madrid, Spain, 2Rheumatology, Hospital Clínico San Carlos, Madrid, Spain

    Background/Purpose: After more than a decade using biological agents (BA), is widely known their efficacy in the treatment of Rheumatoid Arthritis (RA) and their relationship…
  • Abstract Number: 2109 • 2015 ACR/ARHP Annual Meeting

    Racial Disparities in the Risk of Hospitalized Severe Allopurinol Hypersensitivity Syndrome – a US Nationwide Study (2009-2011)

    Na Lu1, Sharan K. Rai2, Jeewoong Choi3 and Hyon K. Choi1, 1Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Harvard Medical School, Boston, MA, 2Experimental Medicine, University of British Columbia, Vancouver, BC, Canada, 3Massachusetts College of Pharmacy and Health Sciences, Boston, MA

    Background/Purpose: Allopurinol is the leading choice of urate-lowering therapy for gout (>95% of treated cases); however, it is associated with the rare but potentially fatal…
  • Abstract Number: 2140 • 2015 ACR/ARHP Annual Meeting

    Drug Specific Risk and Associated Factors for Vasculitis-like Events in Patients Exposed to Tumour Necrosis Factor-α Inhibitor Therapy: Results from the British Society for Rheumatology Biologics Register for Rheumatoid Arthritis

    Meghna Jani1, William G Dixon2, Lianne Kearsley-Fleet3, Ian N. Bruce4,5, Hector Chinoy6,7, Anne Barton6,8, Mark Lunt9, Kath Watson3, Deborah P.M. Symmons1, Kimme L. Hyrich3 and on behalf of the BSRBR-RA, 1Centre for Musculoskeletal Research, University of Manchester, Arthritis Research UK Centre for Epidemiology, Manchester, United Kingdom, 2Manchester Academic Health Sciences Centre, Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, 3Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom, 4Stopford Building, Arthritis Research UK Centre for Epidemiology, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, United Kingdom, 5Central Manchester University Hospital NHS Foundation Trust and Manchester Academic Health Science Centre, NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester, United Kingdom, 6Centre for Musculoskeletal Research, University of Manchester, Manchester, United Kingdom, 7NIHR Manchester Musculoskeletal Biomedical Research Unit, Manchester Academy of Health Sciences, Manchester, United Kingdom, 8NIHR Manchester Musculoskeletal Biomedical Research Unit, Central Manchester Foundation Trust and University of Manchester, Manchester Academy of Health Sciences, Manchester, United Kingdom, 9Arthritis Research UK Centre for Epidemiology, Manchester, United Kingdom

    Background/Purpose: The association between TNF inhibitors (TNFis) and vasculitis-like events, possibly secondary to induction of autoantibodies, has been well reported. However, the incidence, drug-specific differences…
  • Abstract Number: 2157 • 2015 ACR/ARHP Annual Meeting

    Relapse Characteristics and Glucocorticoid Use in Patients with Biopsy-Proven Giant Cell Arteritis

    Matthew J. Koster1, Cristian Labarca2, Cynthia S. Crowson3, Ashima Makol1, Steven R. Ytterberg4, Eric L. Matteson1 and Kenneth J. Warrington1, 1Rheumatology, Mayo Clinic, Rochester, MN, 2Rheumatology, Clinica Alemana Universidad del Desarrollo, Santiago, Chile, 3Health Sciences Research, Mayo Clinic, Rochester, MN, 4Rheumatology Division, Mayo Clinic, Rochester, MN

    Background/Purpose: Relapses in patients with giant cell arteritis (GCA) are common and often lead to higher cumulative use of glucocorticoids. This study aims to evaluate…
  • Abstract Number: 443 • 2015 ACR/ARHP Annual Meeting

    Drug Survival and Reasons for Discontinuation of Biological Disease Modifying Antirheumatic Drug in Thai Patients with Rheumatoid Arthritis: Analysis from the Thai Rheumatic Disease Prior Authorization (RDPA) Register

    Pongthorn Narongroeknawin1, Wanruchada Katchamart2, Parawee Suwannalai3, Nuntana Kasitanon4, Tasanee Kitumnuaypong5, Ajanee Mahakkanukrauh6 and Boonjing Siripaitoon7, 1Rheumatic Disease Unit, Department of Internal Medicine, Phramongkutklao Hospital and Phramongkutklao College of Medicine, Bangkok, Thailand, 2Division of Rheumatology, Department of Medicine, Faculty of Medicine Siriraj hospital, Mahidol University, Bangkok, Thailand, 3Division of Allergy, Immunology and Rheumatology, Department of Medicine, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand, 4Division of Rheumatology, Department of Internal Medicine, Faculty of Medicine, Chiang Mai University, Chiang Mai, Thailand, 5Rheumatology Unit, Department of Internal Medicine, Rajavithi Hospital, Bangkok, Thailand, 6Division of Allergy, Immunology and Rheumatology, Department of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand, 7Division of Rheumatology, Department of Medicine, Faculty of Medicine, Prince of Songkla University, Songkla, Thailand

    Background/Purpose: To evaluate long-term efficacy and safety of biological disease modifying antirheumatic drug (bDMARD) in real-life practice and identify risk factors related to remission and drug discontinuation…
  • Abstract Number: 2167 • 2015 ACR/ARHP Annual Meeting

    Application of Combined Reporting of Benefit and Harm (OMERACT 3×3 methodology) to the Rheumatoid Arthritis Comparison of Active Therapies Trial

    Maarten Boers1,2, Sarah Leatherman3, James R. O'Dell4 and Jeffrey R. Curtis5, 1Rheumatology, Amsterdam Rheumatology and immunology Center, VU University medical center, Amsterdam, Netherlands, 2Amsterdam Rheumatology and immunology Center, VU University Medical Center, Amsterdam, Netherlands, 3MAVERIC CSPCC (151MAV), VA Boston Healthcare System, Boston, MA, 4University of Nebraska Medical Center, Omaha, NE, 5Birmingham VAMC, Birmingham, AL

    Background/Purpose: The Outcome Measures in Rheumatology (OMERACT) Initiative has suggested an analysis of the occurrence of benefit and harm in trials simultaneously, at the individual…
  • Abstract Number: 464 • 2015 ACR/ARHP Annual Meeting

    Biologic Therapy Treatment Complications in the Alberta Aboriginal Population with Rheumatoid Arthritis

    Cheryl Barnabe1, Yufei Zheng2, Arto Ohinmaa2, Brenda Hemmelgarn3, Gilaad Kaplan4, Liam Martin5 and Walter Maksymowych6, 1Cumming School of Medicine, University of Calgary, Calgary, AB, Canada, 2Institute of Health Economics, Edmonton, AB, Canada, 3Division of Nephrology, University of Calgary, Calgary, AB, Canada, 4Division of Gastroenterology, University of Calgary, Calgary, AB, Canada, 5Medicine, University of Calgary, Calgary, AB, Canada, 6Medicine, Medicine, University of Alberta, Edmonton, AB, Canada

    Biologic Therapy Treatment Complications in the Alberta Aboriginal Population with Rheumatoid Arthritis Background/Purpose: Aboriginal people with rheumatoid arthritis (RA) have more severe disease and an…
  • Abstract Number: 1838 • 2014 ACR/ARHP Annual Meeting

    No Increased Risk of Developing a First Invasive Melanoma in Rheumatoid Arthritis Patients Treated with Biologics: Results of a Collaborative Project of 11 European Biologics Registers

    Louise Mercer1, Johan Askling2, Pauline Raaschou3, William Dixon1, Lene Dreyer4, Merete Lund Hetland5, Lene Mellemkjær6, Anja Strangfeld7, Angela Zink8, Florenzo Iannone9, Axel Finckh10, Jakub Zavada11, Helena Canhao12, Fernando Martins13, Xavier Mariette14, Jacques Morel15, Jacques-Eric Gottenberg16, Adele Green1, Victoria Hernández17, Florence Tubach18, Piet van Riel19, Kimme Hyrich20 and Joachim Listing7, 1The University of Manchester, Manchester, United Kingdom, 2Clinical Epidemiology Unit, Karolinska Institutet, Stockholm, Sweden, 3Karolinska Institutet, Stockholm, Sweden, 4Copenhagen University Hospital at Gentofte, Gentofte, Denmark, 5On behalf of all Depts of Rheumatology in Denmark, DANBIO, Glostrup Hospital, Glostrup, Denmark, 6Virus, Lifestyle and Genes, The Danish Cancer Society, Copenhagen, Denmark, 7German Rheumatism Research Center, Berlin, Germany, 8German Rheumatism Research Centre and Charité University Medicine, Berlin, Germany, 9Reumatologia Universita e Policlinico di Bari, Bari, Italy, 10Department of Medical Specialities, University of Geneva, Geneva, Switzerland, 11Charles University, Prague, Czech Republic, 12Rheumatology Research Unit, Instituto de Medicina Molecular, Universidade de Lisboa, Lisbon, Portugal, 13Instituto de Medicina, Universidade de Lisboa, Lisbon, Portugal, 14rheumatology, Université Paris-Sud, Le Kremlin Bicêtre, France, 15Universite´ Montpellier, Montpellier, France, 16Department of rheumatology CHU, Strasbourg, France, 17BIOBADASER Registry, Madrid, Spain, 18INSERM, Universite Paris Diderot, Paris, France, 19Radboud University Medical Centre, Nijmegen, Netherlands, 20Arthritis Research UK Centre for Epidemiology, The University of Manchester, Manchester, United Kingdom

    Background/Purpose: Swedish and Danish national biologics registers (*) have reported a possible increase in melanoma risk with TNF inhibitors.  Since melanomas are uncommon, the association…
  • Abstract Number: 1800 • 2014 ACR/ARHP Annual Meeting

    Objectively Measured Sedentary Behavior Is a Distinct Risk Factor from Low Moderate-to-Vigorous Activity in Predicting Subsequent Frailty: Evidence from Osteoarthritis Initiative

    Jing Song1, Lee A. Lindquist1, Rowland W. Chang1, Pamela A. Semanik2, Linda S. Ehrlich-Jones3, Jungwha Lee4, Min-Woong Sohn1 and Dorothy D. Dunlop1, 1Northwestern University Feinberg School of Medicine, Chicago, IL, 2Rush University Medical Center, Chicago, IL, 3Rehabilitation Institute of Chicago, Chicago, IL, 4Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, IL

    Background/Purpose: Physical frailty represents a state of high vulnerability for adverse health outcomes including disability and mortality. Physical activity interventions to improve health have largely…
  • Abstract Number: 1319 • 2014 ACR/ARHP Annual Meeting

    Safety of Rituximab in Treating Pediatric Rheumatologic Disease

    Arunima Agarwal1, Anusha Ramanathan2 and Rhina Castillo3, 1Pediatric Rheumatology, Children's Hospital of Los Angeles, Los Angeles, CA, 2Rheumatology, Children's Hospital Los Angeles, Los Angeles, CA, 3Pediatric Rheumatology, Childrens Hospital Los Angeles, Los Angeles, CA

    Background/Purpose Rituximab is a chimeric human/murine monoclonal antibody directed against the B cell specific antigen CD20. There is growing evidence that suggests Rituximab may also…
  • Abstract Number: 848 • 2014 ACR/ARHP Annual Meeting

    Malignant Progression of Precancerous Lesions of the Uterine Cervix Following DMARD Therapy in Female Arthritis Patients

    René Cordtz1, Lene Mellemkjær2, Bente Glintborg1, Merete Lund Hetland3 and Lene Dreyer1, 1Department of Rheumatology, Copenhagen University Hospital Gentofte, Hellerup, Denmark, 2Virus, Lifestyle and Genes, The Danish Cancer Society, Copenhagen, Denmark, 3DANBIO Registry and Department of Rheumatology., Copenhagen University Hospital Glostrup. On behalf of all departments of Rheumatology in Denmark., Glostrup, Denmark

    Background/Purpose Recent studies have found that a high proportion of female rheumatoid arthritis (RA) patients are chronic carriers of high-risk HPV-strains and that these patients…
  • Abstract Number: 503 • 2014 ACR/ARHP Annual Meeting

    Does a Higher Dose of Folic Acid Reduce Adverse Effects of Methotrexate in Rheumatoid Arthritis? a Randomized Controlled Trial

    Varun Dhir1, Amit Sandhu1, Jasbinder Kaur2, Nidhi Gupta1, Prabhdeep Kaur1, Ankita Sood1, Aman Sharma3 and Shefali Sharma1, 1Postgraduate Institute of Medical Education and Research, Chandigarh, India, 2Government Medical College and hospital Sector 32, Chandigarh, India, 3Internal Medicine (Rheumatology Unit), Postgraduate Institute of Medical Education and Research, Chandigarh, India

    Background/Purpose There is good evidence that folic acid 5-10mg per week leads to reduction in methotrexate (MTX) toxicity in rheumatoid arthritis (RA). However, this data…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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