Abstracts tagged "Administrative Data"

Abstract Number: 2051 • ACR Convergence 2025
Clinical Burden of Illness Among Patients with Immunoglobulin-G4-Related Disease in the United States
Sushmitha Inguva¹, Emma Culver², Pallavi Rane¹, Laura Moore-Schiltz³, melissa rosen⁴, Kristina Patterson⁴, Donna McMorrow³, Zulkarnain Pulungan⁵, Yasmin Hernandez-Barco⁶ and John Stone⁷, ¹Amgen Inc., Thousand Oaks, ²John Radcliffe Hospital; University of Oxford, Oxford, United Kingdom, ³Inovalon, Bowie, MD, ⁴Amgen Inc., Thousand Oaks, CA, ⁵Inovalon, Bowie, ⁶Massachusetts General Hospital; Harvard Medical School, Boston, MA, ⁷Massachusetts General Hospital , Harvard Medical School, Concord, MA
Background/Purpose: Immunoglobulin G4-related disease (IgG4-RD) is a multi-organ, immune-mediated condition. Timely treatment is critical, as disease flares often result in increased inflammation and organ damage.…
Abstract Number: 1015 • ACR Convergence 2025
Refining Administrative Algorithms For Accurate Identification of Patients with Systemic Sclerosis In Trinetx Research Network
Gulsen Ozen¹, Michael O'Rorke², Paul Romitti² and Robyn Domsic³, ¹University of Iowa, Carver College of Medicine, Division of Immunology, Coralville, IA, ²University of Iowa College of Public Health, Department of Epidemiology, Iowa City, IA, ³University of Pittsburgh, Pittsburgh, PA
Background/Purpose: Large data-driven medical research is invaluable in answering questions about epidemiology, genetics, therapeutics, and outcomes of rare diseases. Systemic sclerosis (SSc) is rare yet…
Abstract Number: 1997 • ACR Convergence 2025
Bone health in patients with gout using real-world U.S. data
Emily Holladay¹, Alexis Woods², Fenglong Xie³, Jingyi Zhang¹, Angelo Gaffo⁴, Jeffrey Curtis⁵ and Brian Lamoreaux⁶, ¹University of Alabama at Birmingham, Birmingham, AL, ²Amgen, Detroit, MI, ³The University of Alabama at Birmingham, Birmingham, AL, ⁴Division of Rheumatology and Clinical Immunology, University of Alabama, Birmingham, AL, USA; Birmingham VA Medical Center, Birmingham, AL, USA, Birmingham, AL, ⁵Foundation for Advancing Science, Technology, Education and Research, Birmingham, AL, ⁶Amgen, Inc., Deerfield, IL
Background/Purpose: Patients with gout may be at high risk for developing osteoporosis and fractures, but osteoporosis may be under-recognized and inadequately managed for gout patients.…
Abstract Number: 0734 • ACR Convergence 2025
Glucocorticoid Exposure and Comorbidity Profile in Patients with Polymyalgia Rheumatica and Giant Cell Arteritis: a multi-country cohort study
Julie Mouchet¹, Lauren Revie², Tim Nguyen³, Liwei Zhao⁴, Valeria Jordan M.⁵, G S Ramakrishna⁶, Linda Grinnell-Merrick³, Atif Adam⁷ and Minouk Schoemaker⁸, ¹Novartis Pharma AG, Basel, Switzerland, ²IQVIA, EMEA, London, United Kingdom, ³Novartis Pharmaceuticals Corporation, East Hanover, NJ, ⁴IQVIA, Real World Solutions, Mölndal, Sweden, ⁵Novartis Pharmaceuticals Corporation, Tenafly, NJ, ⁶Novartis Healthcare Private Limited, Hyderabad, India, ⁷IQVIA Inc, Boston, ⁸IQVIA, Real World Solutions, Amsterdam, Netherlands
Background/Purpose: Polymyalgia rheumatica (PMR) and giant cell arteritis (GCA) are systemic inflammatory conditions that predominantly affect individuals ≥50 years of age. The conditions share overlapping…
Abstract Number: 1931 • ACR Convergence 2025
COSMOS Prevalence of aTTP in SLE
Nisha Sapkota¹, Yevheniia Andriushchenko², Saadia Malik², Sarang Choi² and Sima Terebelo², ¹Interfaith Medical Center, One Broolyn Health, Brooklyn, NY, ²Brookdale Hospital Medical Center, One Brooklyn Health, Brooklyn
Background/Purpose: Systemic lupus erythematosus (SLE) is a complex autoimmune disease with diverse manifestations, including thrombotic thrombocytopenic purpura (TTP), a life-threatening hematologic disorder. The pathogenesis of…
Abstract Number: 0456 • ACR Convergence 2025
Impact of Rheumatoid Arthritis on mortality and other outcomes in Heart failure: A nationwide analysis.
Nisha Sapkota¹, Samuel Sule-saa¹, Yubraj Aryal², Mark Ntow³, Karuna Bista⁴, Parvathy Rajeev³, jemima Alemonai³, Esther Duodu⁵, Brijesh Ghimire³, Pyae Hein³, Jeffrey Sackey⁶, Muhanned Towfig³, Robert Lamptey³, Temesgen Gobena⁷, Daniel Pinkrah⁷ and Mona Pervil Ulysse⁸, ¹Interfaith Medical Center, One Broolyn Health, Brooklyn, NY, ²Geisinger Medical Center, Danville, PA, ³Interfaith Medical Center, One Broolyn Health, Brooklyn, ⁴Montefiore New Rochelle Hospital, New Rochelle, NY, ⁵Broodale Hospital Medical Center, One Broolyn Health, Brooklyn, ⁶Interfaith Medical Center,One Broolyn Health, Brooklyn, ⁷Interfaith Medical Center, Brooklyn, NY, ⁸Interfaith Medical Center, One Brooklyn Health, Brooklyn
Background/Purpose: Rheumatoid arthritis (RA) is a chronic autoimmune disease associated with systemic inflammation and increased cardiovascular risk, particularly heart failure (HF). Patients with RA and…
Abstract Number: 1924 • ACR Convergence 2025
Real-World Treatment Patterns of Patients with Systemic Autoimmune Rheumatic Disease-associated Interstitial Lung Disease After Progression in The United States
Joseph Yang¹, Katy Sadowski¹, Akshay Kharat¹, Ann Chauffe¹ and Tejaswini Kulkarni², ¹Boehringer Ingelheim, Ridgefield, CT, ²University of Alabama at Birmingham, Birmingham, AL
Background/Purpose: Systemic autoimmune rheumatic diseases (SARDs) are a group of autoimmune diseases that affect multiple organ systems, including the lungs. The development of interstitial lung…
Abstract Number: 0433 • ACR Convergence 2025
In-hospital outcomes of patients admitted due to First-Time Pulmonary Embolism with preexisting Rheumatoid Arthritis: A Nationwide Analysis 2016-2022
John Langley¹, Karuna Bista², Clarisse Yapp², Nisha Sapkota³, Shukranta Shrestha² and Sulav Pyakurel¹, ¹Montefiore New Rochelle Hospital, New Rochelle, NY, ²Montefiore New Rochelle Hospital, New Rochelle, ³Interfaith Medical Center, One Brooklyn Health, Brooklyn, NY
Background/Purpose: Although it has been documented that patients with Rheumatoid Arthritis may be at increased risk of Pulmonary Embolism, other inpatient outcomes remain largely unexplored.…
Abstract Number: 1917 • ACR Convergence 2025
Characterizing the Frequency and Timing of Changes in Patient-Reported Social Risk Factors among Rheumatology Outpatients
Daphne Lew¹, Lauren Seidler², Patrice Odom³, Amy McQueen³, Jessica Williams⁴, Seth Eisen⁵ and Alfred Kim⁴, ¹Washington University in St. Louis School of Medicine, Saint Louis, MO, ²Washington University School of Medicine, Saint Louis, ³Washington University School of Medicine, Saint Louis, MO, ⁴Washington University School of Medicine, St. Louis, MO, ⁵Washington University School of Medicine, St Louis, MO
Background/Purpose: Social risk factors (SRFs) are associated with health outcomes, and patients with chronic conditions often report disproportionately higher rates of SRFs, complicating their disease…
Abstract Number: 0400 • ACR Convergence 2025
Recent Antibiotic Exposure and Response to Treatment of Juvenile Idiopathic Arthritis
Daniel Horton¹, Charu Verma², Sanika Rege², Alicia Iizuka², Matthew Iozzio³, Dawn Koffman³, Stephen Crystal⁴, Amy Davidow⁵, Tobias Gerhard², Lauren Parlett⁶, Carlos Rose⁷ and Brian Strom⁸, ¹Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, ²Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, NJ, USA, New Brunswick, NJ, ³Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, NJ, USA, New Brunswick, ⁴Rutgers Center for Health Services Research, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, ⁵New Jersey Medical School, Newark, NJ, ⁶Carelon Research, Inc, Wilmington, DE, ⁷Thomas Jefferson University, Wilmington, DE, ⁸Rutgers Biomedical and Health Sciences, New Brunswick
Background/Purpose: Juvenile idiopathic arthritis (JIA), the most common pediatric rheumatic disease, has been tied to microbiome disruption (dysbiosis). Dysbiosis in adults with arthritis affects response…
Abstract Number: 1909 • ACR Convergence 2025
Trends of venous thromboembolism after total joint replacement in the United Kingdom after the introduction of NICE guidelines.
Subhashisa Swain¹, Nadja Leith², Sarah Brown², Cynthia Wright Drakesmith², Jonathan Rees³, Clare Bankhead⁴ and John Powell⁴, ¹Keele University, University of Oxford, Keele, United Kingdom, ²University of Oxford, Oxford, United Kingdom, ³NDORMS, University of Oxford, Oxford, United Kingdom, ⁴NDPCHS, University of Oxford, Oxford, United Kingdom
Background/Purpose: Joint replacement (JR) surgery is one of the preferred management for end-stage arthritis. Venous Thromboembolism (VTE) is one of the major post-surgical complications after…
Abstract Number: 0399 • ACR Convergence 2025
External Validation of Claims-based Algorithms for Newly Diagnosed Juvenile Idiopathic Arthritis
Daniel Horton¹, Lauren Parlett², Yuyang Zhu³, Sanika Rege⁴, Patricia Hoffman⁵, Daniel Reiff⁶, Sarah McGuire⁷, Sonia Pothraj⁸, Cynthia Salvant⁹, Lakshmi Moorthy¹, Cecilia Huang⁴, Dawn Koffman⁴, Matthew Iozzio³, Alicia Iizuka⁴, Kevin Schott², Stephen Crystal¹⁰, Amy Davidow¹¹, Tobias Gerhard⁴, Kevin Haynes¹², Brian Strom¹³, Daniel Beachler² and Carlos Rose¹⁴, ¹Department of Pediatrics, Rutgers Robert Wood Johnson Medical School, New Brunswick, NJ, ²Carelon Research, Inc, Wilmington, DE, ³Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, NJ, USA, New Brunswick, ⁴Rutgers Center for Pharmacoepidemiology and Treatment Science, Institute for Health, Health Care Policy and Aging Research, Rutgers University, New Brunswick, NJ, USA, New Brunswick, NJ, ⁵Hospital for Special Surgery, New York, NY, ⁶Boys Town National Research Hospital, Boys Town, ⁷Department of Obstetrics and Gynecology, Cooper Medical School, Camden, Camden, NJ, ⁸Washingtonville Pediatrics, Washingtonville, NY, ⁹Albany Medical Center, Albany, NY, ¹⁰Rutgers Center for Health Services Research, Institute for Health, Health Care Policy and Aging Research, New Brunswick, NJ, ¹¹New Jersey Medical School, Newark, NJ, ¹²Janssen Research & Development, Titusville, NJ, ¹³Rutgers Biomedical and Health Sciences, New Brunswick, ¹⁴Thomas Jefferson University, Wilmington, DE
Background/Purpose: Administrative claims databases enable research in large populations with JIA. We previously showed that machine learning (ML)-based algorithms accurately identify new JIA diagnoses within…
Abstract Number: 1901 • ACR Convergence 2025
Epidemiology of Adult-Onset Still’s Disease in South Korea: A Nationwide Study Using Health Insurance Claims Data
Mihye Kwon¹, Younghee Jung², Chung-il Joung¹ and Jeeyoung Hong¹, ¹Konyang University Hospital, Daejeon, Republic of Korea, ²Chungnam National University Hospital, Daejeon, Republic of Korea
Background/Purpose: Adult-onset Still’s disease (AOSD) is a rare systemic autoinflammatory disorder characterised by heterogeneity in clinical course and long-term outcomes. Despite its rarity being recognised…
Abstract Number: 0283 • ACR Convergence 2025
The Performance of Rule-Based Algorithms to Identify Patients With Idiopathic Inflammatory Myopathies in Electronic Health Records
Ana Valle¹, Amy Vo², Rochelle Castillo¹, Yumeko Kawano³, Leah Santacroce³, Daniel Solomon⁴, Katherine Liao³ and Candace Feldman³, ¹Brigham and Women's Hospital, Brookline, MA, ²Harvard Medical School, Boston, ³Brigham and Women's Hospital, Boston, MA, ⁴Division of Rheumatology, Inflammation, and Immunity, Brigham and Women's Hospital, Boston, MA
Background/Purpose: Idiopathic inflammatory myopathies (IIM; including dermatomyositis, polymyositis, and inclusion body myositis) are heterogenous systemic inflammatory conditions that cause significant disability and morbidity. The study…
Abstract Number: 1883 • ACR Convergence 2025
Temporal Patterns of Cardiometabolic Comorbidities Before and After Psoriatic Arthritis Diagnosis: A Nationwide Retrospective Study from Poland.
Batko Bogdan¹, Mateusz Szeląg², Krzysztof Batko³, Magdalena Krajewska-Włodarczyk⁴, Zbigniew Żuber⁵, Marcin Stajszczyk⁶, Brygida Kwiatkowska⁷ and Tomasz Guzik⁸, ¹Department of Rheumatology and Immunology, Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski University, Krakow, Poland, Kraków, Poland, ²Ministry of Health, Warsaw, Poland, ³Department of Dermatology, University Hospital in Krakow, Poland, Krakow, Poland, ⁴University of Warmia & Mazury, Olsztyn, Poland, ⁵Department of Pediatrics, Faculty of Medicine and Health Sciences, Andrzej Frycz Modrzewski University, Krakow, Poland, Krakow, Poland, ⁶Department of Rheumatology and Autoimmune Diseases, Silesian Center for Rheumatology, Orthopedics and Rehabilitation, Ustroń, Poland, Ustron, Poland, ⁷Clinic of Early Arthritis, National Institute of Geriatrics, Rheumatology and Rehabilitation, Warsaw, Poland, Warsaw, Poland, ⁸BHF Centre for Research Excellence, Centre for Cardiovascular Sciences, The University of Edin-burgh, Edinburgh, UK, Edinburgh, United Kingdom
Background/Purpose: While the association between psoriatic arthritis (PsA) and cardiometabolic disorders is established, the temporal sequence and progression of these comorbidities remain poorly characterized. To…

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