ACR Meeting Abstracts

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Abstracts tagged "adhesion molecules and epigenetics"

  • Abstract Number: 2636 • 2017 ACR/ARHP Annual Meeting

    EZH2 Modulates the DNA Methylome and Controls T Cell Adhesion through Junctional Adhesion Molecule-a in Lupus Patients

    Pei-Suen Tsou1, Patrick Coit1, Nathan Kilian2 and Amr H Sawalha1, 1Division of Rheumatology, University of Michigan, Ann Arbor, MI, 2Rheumatology, University of Michigan, Ann Arbor, MI

    Background/Purpose: EZH2 is an epigenetic regulator that trimethylates lysine 27 of histone 3 (H3K27me3) and modulates DNA methylation patterns. We have previously suggested that EZH2…
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