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Abstracts tagged "Adenosine receptors and osteoclastogenesis"

  • Abstract Number: 1964 • 2012 ACR/ARHP Annual Meeting

    Rolofylline, an Adenosine A1R Antagonist, Acts As an Inverse Agonist to Inhibit Osteoclast Differentiation

    Wenjie He1 and Bruce N. Cronstein2, 1Dept of Med, Div of Rheum, NYU, New York, NY, 2Internal Medicine, NYU School of Medicine, Division of Rheumatology, New York, NY

    Background/Purpose: Previous work from our laboratory has uncovered a critical role of adenosine A1 receptor (A1R) in osteoclast formation both in vivo and in vitro.…
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