Abstracts tagged "adaptive immunity and Cell Signaling"

Abstract Number: 971 • 2019 ACR/ARP Annual Meeting
B Cell ROCK1 Promotes Germinal Center Responses and Is Required for Optimal Humoral Immunity
Edd Ricker¹, Danny Flores-Castro ², Sanjay Gupta ³, Andrew Cheng ³, Yurii Chinenov ³, Tania Pannellini ², Young-Bum Kim ⁴ and Alessandra Pernis ⁵, ¹Hospital for Special Surgery, New York, NY, ²Autoimmunity and Inflammation Program, Hospital for Special Surgery, New York, ³Hospital for Special Surgery, New York, ⁴Beth Israel Deaconess Medical Center, Boston, MA, ⁵1.Autoimmunity and Inflammation Program, Hospital for Special Surgery. 2.David Z. Rosensweig Genomics Research Center, Hospital for Special Surgery. 3.Department of Medicine, Weill Cornell Medical College, Cornell University, New York
Background/Purpose: Rho GTPases, such as RhoA, have emerged as important regulators of lymphocyte biology owing to their ability to be rapidly activated downstream of a…

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Abstracts tagged "adaptive immunity and Cell Signaling"

B Cell ROCK1 Promotes Germinal Center Responses and Is Required for Optimal Humoral Immunity