Abstracts tagged "adalimumab and interleukins (IL)"

Abstract Number: 648 • 2016 ACR/ARHP Annual Meeting
ABT-122, an Anti-TNF/Anti-IL-17 Dual Variable Domain Antibody, Alters T Cell Responses in Human Subjects
Melanie Ruzek^1,2, Mark Konrad², Donna Conlon³, Kristie M. Grebe², Anthony Slavin³, Heikki T. Mansikka⁴, Carolyn Cuff³ and Robert J. Padley⁴, ¹Immunology Pharmacology, AbbVie Bioresearch Center, Worcester, MA, ²Immunology Discovery, AbbVie, Worcester, MA, ³Immunology Discovery, AbbVie Bioresearch Center, Worcester, MA, ⁴AbbVie Inc., North Chicago, IL
Background/Purpose: ABT-122 is a dual variable domain antibody which neutralizes both TNF and IL-17 and is in Phase II trials for rheumatoid arthritis (RA) and…