Abstracts tagged "ACPA and Periodontitis"

Abstract Number: 61 • 2018 ACR/ARHP Annual Meeting
A Human ACPA Monoclonal Antibody Is Preferably Localized at Inflammatory Gingival Tissue and Activates Osteoclastogenensis in Porphyromonas Gingivalis Infected SKG Mouse
Kazuhisa Ouhara¹, Tatsuhiko Ozawa², Syuichi Munnaga¹, Tatsuomi Kuranobu³, Yuta Hamamoto¹, Toshihisa Kawai⁴, Eiji Sugiyama⁵ and Hidemi Kurihara¹, ¹Periodontal Medicine, Hiroshima University, Hiroshima, Japan, ²Department of Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan, ³Clinical Immunology and Rheumatology, HIroshima University Hospital, Hiroshima, Japan, ⁴Periodontology, Nova Southeastern University College of Dental Medicine, Fort Lauderdale, FL, ⁵Department of Clinical Immunology and Rheumatology, Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan
Background/Purpose: Periodontal disease (PD) is the chronic inflammatory disease caused by the infection of periodontopathogenic bacteria, Porphyromonas gingivalis (Pg). Pg infection is known as major…