ACR Meeting Abstracts

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Abstracts tagged "ACPA and Periodontitis"

  • Abstract Number: 61 • 2018 ACR/ARHP Annual Meeting

    A Human ACPA Monoclonal Antibody Is Preferably Localized at Inflammatory Gingival Tissue and Activates Osteoclastogenensis in Porphyromonas Gingivalis Infected SKG Mouse

    Kazuhisa Ouhara1, Tatsuhiko Ozawa2, Syuichi Munnaga1, Tatsuomi Kuranobu3, Yuta Hamamoto1, Toshihisa Kawai4, Eiji Sugiyama5 and Hidemi Kurihara1, 1Periodontal Medicine, Hiroshima University, Hiroshima, Japan, 2Department of Immunology, Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama, Toyama, Japan, 3Clinical Immunology and Rheumatology, HIroshima University Hospital, Hiroshima, Japan, 4Periodontology, Nova Southeastern University College of Dental Medicine, Fort Lauderdale, FL, 5Department of Clinical Immunology and Rheumatology, Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan

    Background/Purpose: Periodontal disease (PD) is the chronic inflammatory disease caused by the infection of periodontopathogenic bacteria, Porphyromonas gingivalis (Pg). Pg infection is known as major…
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