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Abstracts tagged "abatacept and monocytes"

  • Abstract Number: 2037 • 2018 ACR/ARHP Annual Meeting

    CTLA4 Signaling Down-Regulates Fcγ Receptor I Expression on Circulating Monocytes: A Potential Mechanism of Action of Abatacept for RA

    Ryosuke Fukue, Yuka Okazaki and Masataka Kuwana, Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan

    Background/Purpose: Abatacept is a recombinant fusion protein comprising cytotoxic T lymphocyte antigen 4 (CTLA4) and Fc region of immunoglobulin (Ig), which is efficacious against rheumatoid…
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