Abstract Number: 2037 • 2018 ACR/ARHP Annual Meeting
CTLA4 Signaling Down-Regulates Fcγ Receptor I Expression on Circulating Monocytes: A Potential Mechanism of Action of Abatacept for RA
Background/Purpose: Abatacept is a recombinant fusion protein comprising cytotoxic T lymphocyte antigen 4 (CTLA4) and Fc region of immunoglobulin (Ig), which is efficacious against rheumatoid…