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Abstracts tagged "8-hydroxydeoxyguanine and DNA"

  • Abstract Number: 2036 • 2019 ACR/ARP Annual Meeting

    Mitochondrial DNA: A Potential Trigger of Cyclic GMP-AMP Synthase Activation in Systemic Lupus Erythematosus

    Jie An1, Bhargavi Duvvuri 1, Xizhang Sun 1, Lena Tanaka 1, Christian Lood 1 and Keith Elkon 1, 1University of Washington, Seattle

    Background/Purpose: Approximately 70% of patients with Systemic Lupus Erythematosus (SLE) show a striking Type I Interferon (IFN-I) signature in peripheral blood. Although we have some…
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