Abstracts tagged "8-hydroxydeoxyguanine and DNA"

Abstract Number: 2036 • 2019 ACR/ARP Annual Meeting
Mitochondrial DNA: A Potential Trigger of Cyclic GMP-AMP Synthase Activation in Systemic Lupus Erythematosus
Jie An¹, Bhargavi Duvvuri ¹, Xizhang Sun ¹, Lena Tanaka ¹, Christian Lood ¹ and Keith Elkon ¹, ¹University of Washington, Seattle
Background/Purpose: Approximately 70% of patients with Systemic Lupus Erythematosus (SLE) show a striking Type I Interferon (IFN-I) signature in peripheral blood. Although we have some…

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Abstracts tagged "8-hydroxydeoxyguanine and DNA"

Mitochondrial DNA: A Potential Trigger of Cyclic GMP-AMP Synthase Activation in Systemic Lupus Erythematosus