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Abstracts tagged "25-hydroxyvitamin D"

  • Abstract Number: 50 • ACR/ARP Annual Meeting 2019

    Circulating 25(OH)D, LL-37 and Antimicrobial Protein and Peptide (APP) Levels Are Altered Prior to Onset of Rheumatoid Arthritis

    Vidyanand Anaparti1, Xiaobo Meng 1, Hemshekhar Mahadevappa 1, Irene Smolik 1, Neeloffer Mookherjee 1 and Hani El-Gabalawy 1, 1University of Manitoba, Winnipeg, MB, Canada

    Background/Purpose: Epidemiological studies suggest vitamin D deficiency as a potential risk factor for rheumatoid arthritis (RA) development, a chronic autoimmune disorder highly prevalent in indigenous…
  • Abstract Number: 273 • ACR/ARP Annual Meeting 2019

    Bone Health in Lupus: Findings from the Southern California Lupus Registry

    Vaneet Sandhu, MBBS1 and Sara Johnson 2, 1Loma Linda University, Loma Linda, CA, 2St George's University, Loma Linda, CA

    Background/Purpose: The association of vitamin D deficiency with SLE is well established. While disease activity can itself cause pathologic bone remodeling and reduced vitamin D,…
  • Abstract Number: 2172 • ACR/ARP Annual Meeting 2019

    Depression of Vitamin D Levels After Adult Primary Posterior Spinal Fusion: Are We Adding Insult to Injury?

    Isabel Smith1, Samuel Golenbock 1, Gerald Miley 2 and Scott Tromanhauser 2, 1New England Baptist Hospital, Boston, MA, 2New England Baptist Hospital, Boston

    Background/Purpose: Vitamin D is a steroid hormone metabolized to its active form in the presence of parathyroid hormone in the kidney. Vitamin D is essential…
  • Abstract Number: 2221 • ACR/ARP Annual Meeting 2019

    Bone Metabolism Impairment in Heart Transplant: Results from a Prospective Cohort Study

    Luis Seguro 1, Rosa Pereira 2, Luciana Seguro3, Valeria Caparbo 3, Monica Avila 1, Sandrigo Mangini 1, Iascara Campos 1, Fabio Gaiotto 1, Fabiana Marcondes-Braga 1 and Fernando Bacal 1, 1Instituto do Coracao (InCor), HCFMUSP, Sao Paulo, 2Faculdade de Medicina da Universidade de Sao Paulo, São Paulo, Sao Paulo, Brazil, 3Faculdade de Medicina da Universidade de Sao Paulo, Sao Paulo

    Background/Purpose: Data on prevention of fractures after heart transplant (HTx) are controversial in the literature. Understanding the effects of HTx on bone may guide appropriate…
  • Abstract Number: 2319 • ACR/ARP Annual Meeting 2019

    Are Vitamin D Metabolite Levels at Time of Diagnosis Associated with Long-term Severe Cardiovascular Events in Early Diagnosed Rheumatoid Arthritis Patients, Aggressively Treated During 10 Year Follow Up? Post-hoc Analyses of Observational Data from the CIMESTRA Cohort

    Mette Herly1, Kristian Stengaard-Pedersen 2, Kim Hørslev-Petersen 3, Merete Lund Hetland 4, Mikkel Østergaard 5, Robin Christensen 6, Brian Løgstrup 7, Peter Vestergaard 8, Peter Junker 9 and Torkell Ellingsen 10, 1Odense University Hospital, Odense C, Syddanmark, Denmark, 2Department of Rheumatology, Department of Clinical Medicine, Aarhus University Hospital, Aarhus University, Aarhus, Denmark, Aarhus, Denmark, 3Department of Rheumatology, King Christian X’s Hospital for Rheumatic Diseases Graasten, Denmark, Graasten, Denmark, 4DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, 5Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark, 6Musculoskeletal Statistics Unit, The Parker Institute, Bispebjerg and Frederiksberg Hospital & Department of Rheumatology, Institute of Clinical Research, University of Southern Denmark, Odense University Hospital, Odense, Denmark, 7Aarhus University Hospital, Skejby, Aarhus, Denmark, 8Aalborg University Hospital, Aalborg, Denmark, 9Odense University Hospital, Odense, Denmark, 10Department of Rheumatology, Odense University Hospital, Denmark, Odense, Syddanmark, Denmark

    Background/Purpose: Cardiovascular disease is highly prevalent in Rheumatoid Arthritis (RA) and in non-RA subjects with low vitamin D levels. The aim of the present study…
  • Abstract Number: 2328 • ACR/ARHP Annual Meeting 2018

    Current Factors Associated with Insufficient Vitamin D Status in Patients with Osteoporosis

    Sandeep Dhillon1, Arzoo Alam2, Matthew Wong-Pack3, Arthur Lau4, Karen A. Beattie5 and Jonathan D. Adachi6,7, 1Department of Medicine, McMaster University, Hamilton, ON, Canada, 2McMaster University, Hamilton, ON, Canada, 3University of Toronto, Toronto, ON, Canada, 450 Charlton Avenue East, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada, 5Medicine, McMaster University, Hamilton, ON, Canada, 6Division of Rheumatology, McMaster University, Hamilton, ON, Canada, 7St Joseph's Healthcare Hamilton, Hamilton, ON, Canada

    Background/Purpose: In 2010, the Canadian Osteoporosis guidelines recommended that patients with osteoporosis be supplemented with vitamin D and to achieve serum levels ≥75nmol/L. Past studies,…
  • Abstract Number: 332 • ACR/ARHP Annual Meeting 2017

    Serum 25-Hydroxyvitamin D, Acute Phase Reactants and Disease Activity in Rheumatologic Diseases

    María Lorena Brance1,2, Lucas Ricardo Brun3, Maria Larroude4, Mónica Patricia Sacnun5, Carolina Aeschlimann5, Guillermo Berbotto6, Mariano Palatnik1, Ignacio Chavero1 and Ariel Sánchez7, 1Centro de Reumatología, Rosario, Argentina, 2School of Medicine. Rosario National University., Bone Biology Laboratory, Rosario, Argentina, 3School of Medicine. Rosario National University, Bone Biology Laboratory, Rosario, Argentina, 4Centro de Diagnostico Rossi, Buenos Aires, Argentina, 5Hospital Provincial, Rosario, Argentina, 6Sanatorio Británico, Rosario, Argentina, 7Centro de Endrocrinología., Rosario, Argentina

    Background/Purpose: Previous evidence indicates an association between vitamin D deficiency and autoimmune diseases. The aim of this study was to evaluate serum 25-hydroxyvitamin D (25OHD),…
  • Abstract Number: 2231 • ACR/ARHP Annual Meeting 2015

    Vitamin D Deficiency States Can be Actively Prevented. Results from a Cross-Sectional Study of over 3000 Patients with Rheumatic Diseases

    Elena Nikiphorou1, Pekka Hannonen1, Paula Väre1, Arto Kokko2, Tuomas Rannio3,4 and Tuulikki Sokka-Isler4, 1Jyvaskyla Central Hospital, Jyvaskyla, Finland, 2Jyvaskyla Central Hospital, Jyväskylä, Finland, 3Kuopio University Hospital, Kuopio, Finland, 4Rheumatology, Jyvaskyla Central Hospital, Jyvaskyla, Finland

    Background/Purpose: Vitamin D (D25) deficiency has been an ongoing matter of concern, especially in countries at northern latitudes. The effects of D25 deficiency in patients…
  • Abstract Number: 2685 • ACR/ARHP Annual Meeting 2015

    High Levels of 25(OH)D Are Associated with Lower Disease Activity in Patients with Newly Diagnosed Rheumatoid Arthritis

    Linda Rasch1, Nicole Konijn1, Yvonne Krul-Poel2, Lilian van Tuyl1, Hennie Raterman1, Marieke ter Wee1, Debby den Uyl1, Suat Simsek2, Michael Nurmohamed1,3 and Willem Lems1,3, 1Amsterdam Rheumatology and immunology Center, location VU University Medical Center, Department of Rheumatology, Amsterdam, Netherlands, 2Department of Internal Medicine, Medical Center Alkmaar, Alkmaar, Netherlands, 3Amsterdam Rheumatology and immunology Center, location Reade, Amsterdam, Netherlands

    Background/Purpose: Vitamin D deficiency is highly common in patients with rheumatoid arthritis (RA) (1). In vitro, vitamin D has anti-inflammatory effects and vitamin D has…
  • Abstract Number: 2957 • ACR/ARHP Annual Meeting 2015

    25-Hydroxyvitamin D3 Deficiency Independently Predicts Cognitive Impairment in Patients with Systemic Lupus Erythematosus: Results from a Controlled Study

    Sen Hee Tay1,2 and Anselm Mak2,3, 1National University of Singapore, Singapore, Singapore, 2National University Health System, Singapore, Singapore, 3Medicine, National University of Singapore, Singapore, Singapore

    Background/Purpose: Cognitive dysfunction has been reported in 20-80% of systemic lupus erythematosus (SLE) patients.  Converging evidence has indicated the importance of vitamin D as a…
  • Abstract Number: 2279 • ACR/ARHP Annual Meeting 2012

    Genetic Markers for Circulating Vitamin D and the Associations with Risk of Systemic Lupus Erythematosus

    Linda T. Hiraki1, Adrienne H. Williams2, Arun-Prasad Manoharan3, Peter Kraft4, Carl D. Langefeld5, Robert R. Graham6 and Elizabeth W. Karlson7, 1Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard School of Public Health, Boston, MA, 2Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, 3Genentech, Inc., 4Program in Molecular and Genetic Epidemiology, Harvard School of Public Health, Boston, MA, 5Center for Public Health Genomics and Department of Biostatistical Sciences, Wake Forest School of Medicine, Winston-Salem, NC, 6ITGR Human Genetics, Genentech, Inc., South San Francisco, CA, 7Division of Rheumatology, Immunology and Allergy, Brigham and Women's Hospital, Harvard Medical School, Boston, MA

    Background/Purpose: Systemic lupus erythematosus (SLE) is a complex, life threatening autoimmune disease and a presumed consequence of susceptibility genes interacting with environmental exposures. Vitamin D…
  • Abstract Number: 1557 • ACR/ARHP Annual Meeting 2012

    What Percentage of Postmenopausal Women Younger Than Age 65 Years Have Low Bone Mineral Density At a Family Health Center?

    Marvin Vaishnani1 and Feyrouz T. Al-Ashkar2, 1Rheumatic and Immunologic diseases, Cleveland Clinic,Lorain Institute, Lorain, OH, 2Rheumatic and Immunologic Diseases, Cleveland Clinic,Lorain Institute, Lorain, OH

    Background/Purpose: Many younger women, < 65 years of age may have low bone mineral density (BMD) that remains undetected in clinical practice due to following…
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