Session » Systemic Sclerosis, Fibrosing Syndromes and Raynaud's – Pathogenesis, Animal Models and Genetics - Poster II

Date: Monday, November 14, 2016

Time: 9:00AM-11:00AM

Meeting: 2016 ACR/ARHP Annual Meeting

9:00AM-11:00AM: Abstract Number: 1857

A Novel Highly Selective 5-Hydroxytryptamine 2B (5-HT2B) Receptor Antagonist Ameliorating Fibrosis in Preclinical Models of Systemic Sclerosis

9:00AM-11:00AM: Abstract Number: 1860

Activating Transcription Factor 3 – a New Linkage Between Vasculopathy and Organ Fibrosis in Systemic Sclerosis

9:00AM-11:00AM: Abstract Number: 1848

Adenosine A2A Receptor (A2AR) Stimulates Collagen Type III Synthesis Via β-Catenin Activation in Vitro and in Vivo

9:00AM-11:00AM: Abstract Number: 1846

Cutaneous and Visceral Fibrosis Induced By Endothelial Cell-Specific Constitutive Activation of TGF-β1 Signaling in Mice

9:00AM-11:00AM: Abstract Number: 1852

Decreased Expression of Sirtuin 7 By Lung Fibroblasts from Patients with Scleroderma Contributes to Elevated Collagen Production

9:00AM-11:00AM: Abstract Number: 1856

Discovery of a Small Molecule Inhibitor of the Wnt Pathway (SM04755) As a Potential Topical Treatment for Scleroderma

9:00AM-11:00AM: Abstract Number: 1849

Fibroblast Growth Factor 9/ Fibroblast Growth Factor Receptor 3 Signaling Is Upstream of Several Profibrotic Pathways and Induces Fibroblast Activation and Tissue Fibrosis in SSc

9:00AM-11:00AM: Abstract Number: 1859

Fucosyltransferase-1 Mediated Fucosylation of TGF-βR1 Is Critical to TGF-β Signaling in Scleroderma and in Bleomycin-Induced Fibrosis

9:00AM-11:00AM: Abstract Number: 1866

Human and Experimental Tracheal Stenosis Is Characterized By a TGF-β-Dependent Fibrotic Component

9:00AM-11:00AM: Abstract Number: 1854

Increased Percentage of CD204/CD206 Double Positive Monocytes Correlates with Specific Lung and Skin Involvement Parameters and an “Active” Capillaroscopic Pattern of Microangiopathy in Systemic Sclerosis Patients

9:00AM-11:00AM: Abstract Number: 1853

Klf5+/-;Fli1+/- Mice Recapitulate Protracted Wound Healing and Cardiac and Intestinal Involvement Associated with Systemic Sclerosis

9:00AM-11:00AM: Abstract Number: 1862

Modelling Healthy and Scleroderma Fibrotic Skin in Vitro: Mechanical Stress Alters Macrophage Cytokine Expression and Triggers Signalling Via the Mechano-Sensing Transcription Factor Myocardin-Related Transcription Factor-a

9:00AM-11:00AM: Abstract Number: 1861

Modelling the Interaction Between Disease Microenvironment and Mesenchymal Cells in Systemic Sclerosis

9:00AM-11:00AM: Abstract Number: 1864

No Evidence of Association of ATP8B4 F436L missense Variant in a Large Systemic Sclerosis Cohort

9:00AM-11:00AM: Abstract Number: 1863

Non-Invasive Investigation of Perfusion, Microvascular Structure, Erythema, Oxidative Stress and Oxygenation in Healthy Controls and in Patients with Primary and Secondary Raynaud’s Phenomenon

9:00AM-11:00AM: Abstract Number: 1850

Optimization of a Murine Model to Recapitulate Dermal and Pulmonary Features of SSc

9:00AM-11:00AM: Abstract Number: 1858

Phenotypical and Functional Characteristics of in Vitro Expanded Adipose-Derived Mesenchymal Stem Cells from Patients with Systemic Sclerosis

9:00AM-11:00AM: Abstract Number: 1855

Phosphodiesterase-5 Inhibitors Attenuate Fibrotic Phenotype and Restore Anti-Fibrotic Resopnses of Cutaneous Fibroblasts in Patients with Scleroderma

9:00AM-11:00AM: Abstract Number: 1845

TGF-β-Induced Tissue Fibrosis Is Abrogated in Mice Containing a Constitutive Genetic Deletion of Nox4 (Nox4 knockout)

9:00AM-11:00AM: Abstract Number: 1851

The Effect of Narrow Band Ultraviolet A1 Light on Bleomycin-Induced Mouse Model of Scleroderma

9:00AM-11:00AM: Abstract Number: 1865

Urinary Cell Adhesion Molecules As Markers of Renal Involvement in Systemic Sclerosis

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