Session » RA – Etiology and Pathogenesis Poster

Date: Sunday, November 13, 2022

Time: 9:00AM-10:30AM

Meeting: ACR Convergence 2022

9:00AM-10:30AM: Abstract Number: 0593

A New Cytokine Interleukin 40 Is Elevated in the Serum of Patients with Early Rheumatoid Arthritis and Associates with Autoantibodies and Neutrophil Activation

9:00AM-10:30AM: Abstract Number: 0628

A Positive-feedback Model for the Contribution of Virus-Specific T Cells to the Development of Rheumatoid Arthritis

9:00AM-10:30AM: Abstract Number: 0621

Altered Immunological Circadian Rhythms and the Effect of Treatment with Glucocorticoids on Circadian Rhythms of Immune Cells in Patients with Rheumatoid Arthritis: Bring Back the Rhythm

9:00AM-10:30AM: Abstract Number: 0604

Altered Metabolic State in Myeloid Precursors and Mature Cells Within Rheumatoid Arthritis

9:00AM-10:30AM: Abstract Number: 0598

An Arthritogenic Strain of Subdoligranulum Specifically Detectable in the Feces of Individuals At-risk for and with Rheumatoid Arthritis Is Bound by ACPA and Stimulates Th17 Cell Activation in Those with Rheumatoid Arthritis

9:00AM-10:30AM: Abstract Number: 0592

Autoantibodies Targeting Malondialdehyde-modifications Are Potential Mediators of Inflammation and Bone Loss in RA, Acting via Macrophage and Osteoclast Regulatory Pathways

9:00AM-10:30AM: Abstract Number: 0607

Cadherin 6 Regulates Rheumatoid Arthritis Fibroblasts-Like Synoviocyte Aggressiveness

9:00AM-10:30AM: Abstract Number: 0624

CD20+ T Cells in the Synovial Fluid of Patients with Rheumatoid Arthritis Suggest a Role for Trogocytosis in Disease Pathogenesis and Activity

9:00AM-10:30AM: Abstract Number: 0602

Cellworks Biosimulation Model (CBM) for Rheumatoid Arthritis (RA), Accurately Captures Patient’s Disease Activity at the Molecular Level Using Their Omics Data and Can Bring Personalization to Treatment Selection in RA

9:00AM-10:30AM: Abstract Number: 0605

Citrullinated Peptide-Specific ACPA Are Present in the Female Genital Tract in Premenopausal Women with and Without RA

9:00AM-10:30AM: Abstract Number: 0622

Commensal Reactive T-cells Display Diverse Phenotype in Rheumatoid Arthritis Patients

9:00AM-10:30AM: Abstract Number: 0600

Correlates Between Rheumatoid Arthritis Clinical Factors and Synovial Cell Phenotypes: Data from the Accelerated Medicines Partnership

9:00AM-10:30AM: Abstract Number: 0591

Deficiency of FUN14 Domain-Containing Protein 1-Mediated Mitophagy in Fibroblast-like Synoviocytes Causes Aggressive Behaviors Leading to Joint Destruction in Rheumatoid Arthritis

9:00AM-10:30AM: Abstract Number: 0619

Differences Between Patients in Remission with Active Rheumatoid Arthritis by Histological and Molecular Comparisons

9:00AM-10:30AM: Abstract Number: 0625

Distinct Effects of JAK Inhibitor and TNF Inhibitors on Circulating B Cell Phenotypes in Rheumatoid Arthritis Patients

9:00AM-10:30AM: Abstract Number: 0626

Elucidating the Expression and Role of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Human Rheumatoid Arthritis Synovial Fibroblasts and a Rat Adjuvant-induced Arthritis Model

9:00AM-10:30AM: Abstract Number: 0599

Expansion of HLA-DR+CD45RAhi Non-lymphoid Cells in Patients with Rheumatoid Arthritis

9:00AM-10:30AM: Abstract Number: 0594

Identification of Peptidylglycine Alpha-Amidating Monooxygenase as a Regulator of Tissue Damage Mediated by Rheumatoid Arthritis Synovial Fibroblasts

9:00AM-10:30AM: Abstract Number: 0617

Killer Cell Immunoglobulin Receptor and Class I HLA Genetic Variability in South-eastern Spanish Rheumatoid Arthritis Patients

9:00AM-10:30AM: Abstract Number: 0609

Macrophage Response to MAA Modified Fibrinogen in the Presence of Peptidyl Arginine Deiminase Inhibitor

9:00AM-10:30AM: Abstract Number: 0606

Mechanism of Joint-Specific Homeobox D10 Regulation in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

9:00AM-10:30AM: Abstract Number: 0590

Molecular Profiling of Normal Human Synovium Reveals Striking Impact of Adipocytes and Homeostatic Cortisol Signaling

9:00AM-10:30AM: Abstract Number: 0620

Neovascularization Is Altered by Rheumatoid Arthritis Synovial Fibroblasts and Canstatin in Vitro and in Vivo

9:00AM-10:30AM: Abstract Number: 0596

Neutrophil Extracellular Traps (NET) Trigger an Enhanced Pro-inflammatory Response in Macrophage Subpopulations in Rheumatoid Arthritis Patients via the Aryl Hydrocarbon Receptor (AhR) Pathway

9:00AM-10:30AM: Abstract Number: 0601

Occupational Inhaled Agents Constitute Major Risk Factors for Rheumatoid Arthritis, Particularly in the Context of Genetic Predisposition and Smoking

9:00AM-10:30AM: Abstract Number: 0610

Patient-derived Organoids Reveal Transcriptional Regulation of Synovial Lining Fibroblast Differentiation

9:00AM-10:30AM: Abstract Number: 0612

Peripheral Blood and Synovial Fluid Natural Killer (NK) and Natural Killer T (NKT) Cell Immunophenotypes in Active Rheumatoid Arthritis and Their Role as Biomarkers of Methotrexate Response

9:00AM-10:30AM: Abstract Number: 0614

Post-translationally Modified Fibrinogen Activated Macrophages Drive the Expression of Fibrotic Genes in Rheumatoid Arthritis Fibroblast-Like Synoviocytes

9:00AM-10:30AM: Abstract Number: 0611

Proteomics Reveals Dysregulated Molecular Mechanisms of Cell Death in Neutrophils in Rheumatoid Arthritis

9:00AM-10:30AM: Abstract Number: 0618

Regulation of IgA Secretion Through PAD2-mediated Citrullination of MZB1

9:00AM-10:30AM: Abstract Number: 0589

Restoration of NAD+ Levels in Rheumatoid Arthritis with NAD+ Boosters as a Novel Therapeutic Strategy to Resolve Acute Inflammation

9:00AM-10:30AM: Abstract Number: 0623

Rheumatoid Synovial Fibroblasts Display Imprinted Memory of Their Synovial Endotype Which Can Be Plastically Modulated by B-cells Crosstalk

9:00AM-10:30AM: Abstract Number: 0615

Semaphorin 5A Suppresses Ferroptosis Through Activation of PI3K-AKT-mTOR Signaling in Rheumatoid Arthritis

9:00AM-10:30AM: Abstract Number: 0616

Serum Proteomic Networks Associate with Pre-clinical Rheumatoid Arthritis Autoantibodies and Longitudinal Outcomes

9:00AM-10:30AM: Abstract Number: 0627

Spatial Transcriptomic Analysis Reveals Vascular Zonation of Myofibroblasts in Rheumatoid Arthritis Synovium

9:00AM-10:30AM: Abstract Number: 0603

Survivin-dependent Regulation of Bivalent Chromatin and Its Relevance for Adaptive Immunity

9:00AM-10:30AM: Abstract Number: 0613

The Subsets of Synovial Fluid Derived Fibroblasts in Clinical Features of Rheumatoid Arthritis

9:00AM-10:30AM: Abstract Number: 0597

TNF-α Utilizes the TWEAK/Fn-14 Axis in Human Rheumatoid Arthritis Synovial Fibroblasts

9:00AM-10:30AM: Abstract Number: 0595

Validation of Urotensin-2 mRNA Expression as Marker for Tocilizumab Non-Response in Early Rheumatoid Arthritis

9:00AM-10:30AM: Abstract Number: 0608

Wnt Pathway Regulators R-spondin 3 and Dickkopf-related Protein 3 Demarcate a Transcriptional Gradient That Drives Synovial Fibroblast Inflammatory Pathology in Rheumatoid Arthritis

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