Session » Genetics, Genomics & Proteomics Poster

10:30AM-12:30PM

Abstract Number: 0898

A Blood Transcriptome Signature Distinguishes Between Diverse Systemic Autoimmune Diseases and Infection

10:30AM-12:30PM

Abstract Number: 0886

A Longitudinal Cohort Study Uncovers Plasma Protein Biomarkers Predating Clinical Onset and Treatment Response of Rheumatoid Arthritis

10:30AM-12:30PM

Abstract Number: 0911

Activating B Cells Facilitates the Discovery of Latent Disease-associated Variants

10:30AM-12:30PM

Abstract Number: 0915

APOH Locus Associated with Higher Anti-Beta-2-Glycoprotein 1 Antibody Levels Paradoxically Protects Against Venous Thromboembolism

10:30AM-12:30PM

Abstract Number: 0900

Association Between Serum Urate, Gout, and Prostatic Cancer in European Male Populations: A Mendelian Randomization Study

10:30AM-12:30PM

Abstract Number: 0907

Association of Rare and Common Genetic Variants in MOCOS with Inadequate Response to Allopurinol

10:30AM-12:30PM

Abstract Number: 0908

Clinical Characteristics of Patients with High SLE-specific and High Multitrait Polygenic Risk – an Investigation of SLE Risk Loci

10:30AM-12:30PM

Abstract Number: 0904

Defining the Function of Disease Variants with CRISPR Editing and Multimodal Single Cell Sequencing

10:30AM-12:30PM

Abstract Number: 0903

Distinct Impacts of Mosaic Loss of Chromosome Y and Genetic Risk on the Age of Onset in Patients with Rheumatoid Arthritis

10:30AM-12:30PM

Abstract Number: 0897

Dynamic eQTLs from Activated Human B Cells Suggest Cell-state Dependent Effects for GWAS Risk Variants in BLK

10:30AM-12:30PM

Abstract Number: 0884

Genetic Architecture Divergence in Sjögren’s Disease Subphenotypes and Populations: Genome-wide Association Study of Ro/SSA+ and Ro/SSA- Cases in European Populations

10:30AM-12:30PM

Abstract Number: 0888

Genetically Determined Peptidylglycine Alpha-amidating Monooxygenase (PAM) Mediated Amidation Regulates Tissue Damage by Rheumatoid Arthritis Synovial Fibroblasts

10:30AM-12:30PM

Abstract Number: 0905

High-Throughput Proteomic Profiling of Sera as a Non-Invasive Method for Identifying Lupus Nephritis Subtypes

10:30AM-12:30PM

Abstract Number: 0894

HOXD13 Regulation of Primary Cilia in Rheumatoid Arthritis Synovial Fibroblasts: Implications for Joint-Specific Pathogenesis

10:30AM-12:30PM

Abstract Number: 0896

Identification of Immune Pathways Regulated by a Non-Coding Variant at DNASE1L3/PXK/PDHB

10:30AM-12:30PM

Abstract Number: 0887

Identification of Rare Variants in Lupus-causing Genes in a Mixed Paediatric and Adult Connective Tissue Disease Cohort

10:30AM-12:30PM

Abstract Number: 0909

Identifying Predictive Serum Soluble Mediators Signatures Specific to ANA+ at Risk of SLE Individuals with Next Generation Proteomics

10:30AM-12:30PM

Abstract Number: 0901

Intergenic Alu Elements Are Uniquely Expressed in Dermatomyositis and Correlate with Interferon Stimulated Genes

10:30AM-12:30PM

Abstract Number: 0916

Isocitrate Dehydrogenase 2 Mutations Are Associated with Autoimmune Rheumatologic Diseases in Chronic Myelomonocytic Leukemia

10:30AM-12:30PM

Abstract Number: 0912

Next-Generation Sequencing in Molecular Genetics of Adult-Onset Still’s Disease: Data from 23 Patients and Literature Review

10:30AM-12:30PM

Abstract Number: 0902

Novel Role of TYK2mechanism in SLE Pathogenesis via T Cell and B Cell Pathways

10:30AM-12:30PM

Abstract Number: 0892

Peptides from Candidate Sjögren’s Disease Autoantigens and Salivary Gland Tissue-Enriched Proteins Eluted from Human Salivary Gland HLA-DR

10:30AM-12:30PM

Abstract Number: 0890

Pervasive Inflammation Poisons Hematopoiesis and Drives Clonal Dominance in VEXAS Syndrome

10:30AM-12:30PM

Abstract Number: 0895

Procoagulant Extracellular Vesicles in Patients with Livedo Reticularis

10:30AM-12:30PM

Abstract Number: 0899

Proteomic Insights into JAK Inhibitor Therapeutic Response in Rheumatoid Arthritis

10:30AM-12:30PM

Abstract Number: 0906

Proteomic Signatures of Difficult-to-Treat Rheumatoid Arthritis: Identifying Predictive Biomarkers

10:30AM-12:30PM

Abstract Number: 0914

RAB19 and Azathioprine-Associated Pancreatic Injury in Patients Taking Azathioprine

10:30AM-12:30PM

Abstract Number: 0910

Reduced Adenosine-Mediated Regulatory Activity Exacerbated by an NT5E Loss of Function Mutation Is Linked to Tissue Inflammation and Hypertension in Systemic Lupus Erythematosus

10:30AM-12:30PM

Abstract Number: 0885

Reproducible Single Cell Annotation of Programs Underlying T-cell Subsets, Activation States, and Functions

10:30AM-12:30PM

Abstract Number: 0917

Role of Mutual Information Profile Shifts in Assessing the Pathogenicity of Mutations on Protein Functions: The Case of Pyrin Mutations in Familial Mediterranean Fever

10:30AM-12:30PM

Abstract Number: 0891

Shared and Disease-Specific Mechanisms of Autoimmunity Using Single Cell Sequencing of Peripheral Immune Cells

10:30AM-12:30PM

Abstract Number: 0913

The Association Between PTPN2 and Leukopenia in New Users of Azathioprine

10:30AM-12:30PM

Abstract Number: 0893

Uncovering Common and Distinctive Molecular Profiles Between Early and Stablished Rheumatoid Arthritis Through Integrative Multi-omics Analysis and Its Association with Disease Status and Clinical Response

10:30AM-12:30PM

Abstract Number: 0889

Unraveling the Progression of Sjögren’s Disease at the Cellular and Histological Level Using Single-cell and Spatial Transcriptomics