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Session » Biology and Pathology of Bone and Joint Poster I: Osteoarthritis Pathogenesis

Date: Monday, November 9, 2015

Time: 9:00AM-11:00AM

Meeting: 2015 ACR/ARHP Annual Meeting

Abstract Number: 1127
Downregulation of nuclear Factor-Erythroid 2-Related Factor (Nrf2)/Heme Oxygenase-1 Axis in Diabetic Cartilage: Towards a Better Phenotyping of diabetes-Related Osteoarthritis
Abstract Number: 1128
Insulin-Induced Cartilage Degradation in Osteoarthritis Is Associated to Defective Autophagy
Abstract Number: 1129
Transthyretin Deposition Accelerates the Development of Experimental Osteoarthritis in Mice
Abstract Number: 1130
Global DNA Methylation Analysis of Osteoarthritic Subchondral Bone Reveals Significant Regional Variation and Similarity to Overlying Cartilage
Abstract Number: 1131
A Histone Deacetylase Inhibitor SAHA Induce MCPIP1 Expression and Suppress IL-6 Expression By Upregulating Cebpα Expression and Downregulating the Expression of Mir-9 in Human OA Chondrocytes
Abstract Number: 1132
Altered Histone 3 Dynamics at the Matrix Metalloproteinase 1 (MMP1) Transcription Start Site Contributes to MMP1 Suppression in Betaine Supplemented Synovial Fibroblasts in Rheumatoid Arthritis
Abstract Number: 1133
Microrna-128 Interference Mitigates the Progression of Keen Osteoarthritis By Regulating Sirtuin-1
Abstract Number: 1134
Identification of Novel Micro-RNAs in IL-1β-Stimulated OA Chondrocytes By Next-Generation Sequencing
Abstract Number: 1135
Krüppel-like Factors (Klfs), Novel Transcriptional Regulators of Articular Chondrocytes That Are Abnormally Expressed in Osteoarthritic Cartilage
Abstract Number: 1136
IL-1β-Induced Stress Granules Sequester COX-2 mRNA and Regulates Its Expression in Human OA Chondrocytes
Abstract Number: 1137
Low Molecular Weight Polyphenol Harpagoside Inhibits IL-1β-Induced Expression of IL-6 By Blocking the Expression and Activity of c-Fos in Primary Human Osteoarthritis Chondrocytes
Abstract Number: 1138
Suppressor of Cytokine Signaling 1 Inhibits Interleukin-1β Induced Matrix Metalloproteinases Expression in Human Chondrocytes By Modulating p38-CREB- C/Ebpβ Pathway
Abstract Number: 1139
Differential Inflammatory Profile in Experimental Models of Arthritis
Abstract Number: 1140
Resident Non-Classical Monocytes Are Critically Important for Tissue Destruction in Arthritis
Abstract Number: 1141
Synovial Ultrasound Power Doppler Enhancement Reflects Multiple Cytokine Expression in Synovial Tissue, Distinguishing Distinct High Macrophage-Associated and Low Inflammation Profiles
Abstract Number: 1142
Joint Specific Function of Synovial Fibroblasts – Integrating Positional Transcriptomes and Anatomic Patterns of Arthritis
Abstract Number: 1143
Reduced Hydrogen Sulfide Synthesis in the Joint, a New Player in the Pathogenesis of Osteoarthritis
Abstract Number: 1144
Effect of PEP-1-Glrx-1 on Catabolic Gene Expression in Human Articular Chondrocytes and in Mouse Carrageenan-Induced Paw Edema Model
Abstract Number: 1145
Expression of Xylosyltransferase-1 Is Modulated By Fibronectin Fragment in Human Articular Chondrocytes
Abstract Number: 1146
Deficiency of TLR2 and TLR4 Impairs Autophagic Flux in Chondrocytes
Abstract Number: 1147
TGFß1 Blocks Chondrocyte Hypertrophy and Increases Cell Viability in Cultured Cartilage Explants but Does Not Protect Against Proteoglycan Loss
Abstract Number: 1148
The Role of TRPC6 in CXCR2-Mediated Chondrocyte Phenotypic Stability
Abstract Number: 1149
The Active Metabolite of Fostamatinib, R406, Only Decreases the Inflammation-Driven Extracellular Matrix Turnover of the Joint at High Concentrations Ex Vivo
Abstract Number: 1150
Novel Chitosan Hydrogels for the Treatment of Osteoarthritis: Mechanical Support, Lubrication and Prevention of Cartilage Degradation in a Rabbit Model of Osteoarthritis
Abstract Number: 1151
The Proteomic Profile of Histological Samples Derived from a Surgical Mouse Model of Osteoarthritis Reveals an Unexpected Mode of Action for the Anti-Aggrecanase-2 Monoclonal Antibody CRB0017
Abstract Number: 1152
Comprehensive Novel Proteomic Analysis of RA Synovial Fluid Highlights the Distinct Protein Profiles of Bone and Cartilage Metabolism

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