Session » (0978–1006) T Cell Biology & Targets in Autoimmune & Inflammatory Disease Poster

Date: Monday, October 27, 2025

Time: 10:30AM-12:30PM

Meeting: ACR Convergence 2025

10:30AM-12:30PM: Abstract Number: 1000

A Deep-Learning Based Approach Uncovers Novel Mediators of Micro-RNA Restraint of Type-2 Immunity

10:30AM-12:30PM: Abstract Number: 1006

AI-Guided Generation and Preclinical Evaluation of an OX40L-IL31 Bispecific Antibody

10:30AM-12:30PM: Abstract Number: 0990

An Fc-engineered Agonistic Anti-PD-1 Antibody Selectively Depletes PD-1+ cells and Attenuates T cell activation in vitro and in vivo in a Xenogeneic Graft-versus-Host Disease (GvHD) model

10:30AM-12:30PM: Abstract Number: 1002

ATF3 Inhibits Pulmonary Fibrosis via CD4+CD25−LAG3+ T Cells

10:30AM-12:30PM: Abstract Number: 0996

Breaking Inflammatory Pathways: ELN28, a Novel Dual TNFα/JAK Inhibitor Drug Conjugate for Chronic Inflammation

10:30AM-12:30PM: Abstract Number: 1005

CD49a Contributes to Binding and Survival of Synovial Resident Memory T cells

10:30AM-12:30PM: Abstract Number: 0983

Detecting Autoreactive CD4+ T Cells Relevant to Mixed Connective Tissue Disease

10:30AM-12:30PM: Abstract Number: 0988

Distinct Effects of Inhibitory Receptor Agonism on RA Synovial CD4+ T Cell Functions

10:30AM-12:30PM: Abstract Number: 0980

Expansion of Viral-Reactive CD8+ T cell Repertoire Stratified by Pathotype in New-onset ACPA+ Rheumatoid Arthritis

10:30AM-12:30PM: Abstract Number: 0992

FoxP3Lo CD4+ T cells are functionally suppressive and expanded in the immune-mediated fibrotic diseases IgG4-related disease and systemic sclerosis

10:30AM-12:30PM: Abstract Number: 0981

GNTI-350: A CAR-Treg Therapy Offering Durable Immune Reset with Improved Safety for B Cell–Driven Autoimmune Diseases

10:30AM-12:30PM: Abstract Number: 0989

Human MAIT cell produce IL-17 independently of IL-23 and TL1A

10:30AM-12:30PM: Abstract Number: 0997

Identification of Novel HLA Class II–Restricted Autoantigens in Scleroderma and Ulcerative Colitis Using TargetScan

10:30AM-12:30PM: Abstract Number: 0978

IL-17A+ HLA-DR-CCR6+ regulatory T cells: Dual role in T cell suppression and synovial inflammation in arthritis.

10:30AM-12:30PM: Abstract Number: 0979

IL-23 upregulates IFN-γ secretion in Th17.1, but not in Th17 or classical Th1 cells

10:30AM-12:30PM: Abstract Number: 0982

Impact of Immunosuppressive Therapies on Shingrix Vaccine Response in Immune-Mediated Inflammatory Diseases

10:30AM-12:30PM: Abstract Number: 0984

Interleukin-21 as a driver of CD8 T cell tissue resident memory and pathogenesis in dermatomyositis

10:30AM-12:30PM: Abstract Number: 0986

LBL-053, A Novel Anti-TL1A/p40 Bispecific Antibody for the Treatment of Autoimmune Disorders.

10:30AM-12:30PM: Abstract Number: 1001

LBL-057, a Novel ADCC Enhanced PD-1 Agonist VHH-Fc Antibody

10:30AM-12:30PM: Abstract Number: 0985

Lupus Skin Shapes a Distinct Inflammatory Milieu that Drives the Skewing of Treg and inflammatory T cells

10:30AM-12:30PM: Abstract Number: 0991

MTHFD2 is a Novel Metabolic Target in Autoimmune Disease

10:30AM-12:30PM: Abstract Number: 0999

Myositis Induced by Histidyl-Transfer tRNA Synthetase is Exacerbated by Membranopathy and Suppressed by Regulatory T Cells

10:30AM-12:30PM: Abstract Number: 0993

NOD2 mutations mediate IL-17 predisposition in patients with Blau syndrome

10:30AM-12:30PM: Abstract Number: 1003

Potent Engineering of Polyfunctional CD8+ T Cells by a Novel In Vivo CAR mRNA Product Candidate (CPTX2309) in a Targeted Lipid Nanoparticle (tLNP) Utilizing CellSeekerTM Technology

10:30AM-12:30PM: Abstract Number: 0998

Preclinical Characterization of a Novel Bi-specific Antibody Targeting IL-23p19 and IL-36R for The Treatment of Autoimmune Diseases

10:30AM-12:30PM: Abstract Number: 0995

Resident Memory T Cells Stimulate Pathogenic Activity in Fibroblast-like Synoviocytes

10:30AM-12:30PM: Abstract Number: 0987

S-4321, a novel dual-cell bifunctional PD-1:FcγRIIb selective agonist antibody for autoimmune disease, maintains expression of PD-1 on target cells and enhances inhibitory receptor expression on T cells in vivo

10:30AM-12:30PM: Abstract Number: 1004

Single-Cell Analysis Reveals Tissue Resident Memory T Cells Heterogeneity in the Joint

10:30AM-12:30PM: Abstract Number: 0994

UTAA91: An Off-the-Shelf Allogeneic CAR-Vδ1T Therapy Leveraging CD19 Nanoantibody for B-cell Depletion and PD-1 Agonist Nanoantibody for Pathogenic T-cell Elimination in Refractory Autoimmune Diseases

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