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Session » (0934–0954) Systemic Lupus Erythematosus – Animal Models Poster

Date: Monday, October 27, 2025

Time: 10:30AM-12:30PM

Meeting: ACR Convergence 2025

10:30AM-12:30PM
Abstract Number: 0946
A Novel Preclinical Tool for Evaluating CD20 Antibody Efficacy Based on BAFF/CD20 Dual-target Humanized Mice
10:30AM-12:30PM
Abstract Number: 0950
Ep300-Catalyzed Rad50 Lactylation Compromises Genomic Stability and Drives CD4+T cells Cell Senescence in SLE
10:30AM-12:30PM
Abstract Number: 0951
Epidermal IFNκ Increases Circulating and Cutaneous Monocytes in a C57/Bl6 Overexpression Mouse Model
10:30AM-12:30PM
Abstract Number: 0939
Exploring the Mechanism of Action and Related Biomarkers of BTK Inhibitor/Degrader in Systemic Lupus Erythematosus
10:30AM-12:30PM
Abstract Number: 0941
In Vivo PanCAR Therapy Utilizing Circular RNA for Treatment of Autoimmune Diseases
10:30AM-12:30PM
Abstract Number: 0944
L-sepiapterin treatment reduces renal cortical gene expression associated with oxidative stress and fibrosis in NZM2410 murine lupus nephritis
10:30AM-12:30PM
Abstract Number: 0947
Mechanisms of anti-NMDAR antibody-mediated neuronal pathology and mitigation by angiotensin II signaling inhibition
10:30AM-12:30PM
Abstract Number: 0937
MRL-lpr Mice Display Altered Nociception: A new model for lupus peripheral neuropathy
10:30AM-12:30PM
Abstract Number: 0945
Nerve Injury-Induced Protein-1 (Ninj1) Deficiency Aggravates Murine Lupus Through Modulation of Macrophage Polarization
10:30AM-12:30PM
Abstract Number: 0953
NMDAR Autoantibody-Induced Neuronal Damage in the Amygdala Mediates Mood and Anxiety Disorders in a Model of Neuropsychiatric Lupus
10:30AM-12:30PM
Abstract Number: 0935
Oral Antibiotic Treatment Reduces Anxiety in a Murine Model of Neuropsychiatric Manifestations of Systemic Lupus Erythematosus
10:30AM-12:30PM
Abstract Number: 0948
Presentation of Apoptotic Cell-Derived Autoantigens in Systemic Autoimmune Disease
10:30AM-12:30PM
Abstract Number: 0940
Resident Macrophages Localize Near Fibroblasts and Drive Reprogramming in Lupus Nephritis Through Direct and Soluble Signaling
10:30AM-12:30PM
Abstract Number: 0938
Short Term Antibiotic Treatment Improves the Neurobehavioral Phenotype of MRL/lpr Mice
10:30AM-12:30PM
Abstract Number: 0942
Sodium-Glucose Co-Transporter 2 Inhibitors Modulate Renal Injury and Autoreactive Plasma Cells in Lupus
10:30AM-12:30PM
Abstract Number: 0949
The Cancer-associated Female-biased Factor VGLL3 Drives Autoimmunity and Fibrosis
10:30AM-12:30PM
Abstract Number: 0934
The Use Of Preclinical Models To Understand Drivers Of Lupus Pathogenesis
10:30AM-12:30PM
Abstract Number: 0952
Therapeutic Potential of PaPE-1 in Reducing TLR7-Mediated Inflammation in a Murine Model of Lupus
10:30AM-12:30PM
Abstract Number: 0943
Type I and Type II IFNs have both independent and overlapping effects on SLE disease severity
10:30AM-12:30PM
Abstract Number: 0936
Ultrasound-Mediated Blood–Brain Barrier Permeabilization Enables Targeted Drug Delivery in a Murine Model of Neuropsychiatric SLE

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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

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