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Abstract Number: 2253 • 2018 ACR/ARHP Annual Meeting
Cardiovascular Disease, Other Purported Risk Factors, and Allopurinol-Associated Severe Cutaneous Adverse Reactions: A General Population-Based Cohort Study
Na Lu¹, Chio Yokose², Hui Xie^1,3, Gloria Li¹, Sharan K. Rai^4,5, Seoyoung C. Kim⁶ and Hyon K. Choi², ¹Arthritis Research Canada, Richmond, BC, Canada, ²Division of Rheumatology, Allergy, and Immunology, Massachusetts General Hospital, Boston, MA, ³Faculty of Health Sciences, Simon Fraser University, Burnaby, BC, Canada, ⁴Division of Rheumatology, Allergy and Immunology, Massachusetts General Hospital, Boston, MA, ⁵Graduate School of Arts and Sciences, Harvard University, Cambridge, MA, ⁶Brigham and Women’s Hospital, Harvard Medical School, Boston, MA
Background/Purpose: A recent US Medicaid study found that in addition to certain races (Asians and Blacks), older age, female sex, chronic kidney disease (CKD), and…
Abstract Number: 2435 • 2018 ACR/ARHP Annual Meeting
Pregnancy Outcomes Among Women with Rare Autoimmune Diseases
Jon Golenbiewski, Amanda M. Eudy and Megan E. B. Clowse, Department of Medicine, Division of Rheumatology and Immunology, Duke University, Durham, NC
Background/Purpose: Autoimmune disease in pregnancy creates the potential for increased complications and poor pregnancy outcomes. There is a paucity of outcomes data in less-common autoimmune…
Abstract Number: 2967 • 2018 ACR/ARHP Annual Meeting
Potent Bifunctional Inhibitors of Xanthine Oxidase and URAT1 Block Fructose-Induced Inflammation Via Increase in AMP Kinase Activity
Laura Gabriela Sánchez Lozada¹, Fernando E. García-Arroyo², J. Gabriel Juárez-Rojas³, Guillermo Gonzaga² and Raymond P. Warrell Jr.⁴, ¹Nephrology, INC Ignacio Chavez, Mexico City, Mexico, ²INC Ignacio Chavez, Mexico City, Mexico, ³INC Ignacio Chavez, Mexoci City, Mexico, ⁴Relburn-Metabolomics, Inc., Westfield, NJ
Background/Purpose: Dietary fructose promotes an increase in uric acid (UA) that may lead to gout. UA itself promotes lipogenesis and inflammation in both gout as…
Abstract Number: 76 • 2017 ACR/ARHP Annual Meeting
TNF-α Potentiates Uric Acid-Induced Interleukin-1β Secretion in Human Neutrophils
Shuzo Sato¹, Makiko Yashiro¹, Tomoyuki Asano¹, Tomohiro Koga², Eiji Suzuki¹, Hiroko Kobayashi¹, Hiroshi Watanabe¹ and Kiyoshi Migita³, ¹Rheumatology, Fukushima Medical University School of Medicine, Fukushima, Japan, ²Department of Immunology and Rheumatology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan, ³Fukushima Medical University School of Medicine, Fukushima, Japan
Background/Purpose: Gout is an inflammatory arthropathy due to the deposition of uric acid (monosodium urate: MSU) crystals in synovial tissue. MSU leads to activate nucleotide-binding…
Abstract Number: 92 • 2017 ACR/ARHP Annual Meeting
Hospital for Special Surgery Academy of Rheumatology Medical Educators: 5 Year Outcomes Demonstrate the Value of Supporting Education Research in the Academic Environment
Jessica R. Berman¹, Juliet Aizer¹, Anne R. Bass², Edward Parrish¹, Laura Robbins³, Michael D. Tiongson⁴ and Stephen A. Paget¹, ¹Rheumatology, Hospital for Special Surgery Weill Cornell Medical College, New York, NY, ²Rheumatology, Hospital for Special Surgery/Weill Cornell Medicine, New York, NY, ³Education & Academic Affairs, Hospital for Special Surgery, New York, NY, ⁴Hospital for Special Surgery, New York, NY
Background/Purpose: It has been previously demonstrated that educators do not receive the same recognition as their colleagues in clinical and basic science, and financial support…
Abstract Number: 104 • 2017 ACR/ARHP Annual Meeting
Utility of a Virtual Rheumatology Clinic for Community Based Internal Medicine Residency Program
Sonam Kiwalkar¹ and Bethany A. Marston², ¹Internal Medicine, Rochester General Hospital, Rochester, NY, ²Rheumatology, University of Rochester, Rochester, NY
Background/Purpose: At our mid-sized community hospital, internal medicine residents have little routine access to subspecialty rheumatology faculty clinical and didactic teaching, which has been reflected…
Abstract Number: 172 • 2017 ACR/ARHP Annual Meeting
Optimizing Precision Medicine By Using Genetics to Assign Diagnostic Prior Probabilities to Patients with Synovitis
Rachel Knevel^1,2,3,4, Chikashi Terao^5,6,7, Jing Cui^1,8, Kamil Slowikowski^2,9,10, TWJ Huizinga³, Elizabeth Karlson¹¹ and Soumya Raychaudhuri^1,2,12,13, ¹Division of Medicine and Rheumatology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ²Medical and Population Genetics Program, Broad Institute of MIT and Harvard, Cambridge, MA, ³Department of Rheumatology, Leiden University Medical Center, Leiden, Netherlands, ⁴Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Bosten, MA, ⁵Laboratory for Statistical Analysis, RIKEN Center for Integrative Medical Sciences, Yokohama, Japan, ⁶Clinical Research Center, Shizuoka General Hospital, Shizuoka, Japan, ⁷Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan, ⁸Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, ⁹Division of Medicine and Rheumatology, Brigham and Women's Hospital, Harvard Medical Schoo, Boston, MA, ¹⁰Division of Genetics, Brigham and Women's Hospital, Harvard Medical Schoo, Boston, MA, ¹¹Rheumatology, Immunology and Allergy, Brigham and Women's Hospital and Harvard Medical School, Boston, MA, ¹²Department of Institute of Inflammation and Repair, University of Manchester, Manchester, United Kingdom, ¹³Division of Genetics, Brigham and Women's Hospital, Harvard Medical School, Boston, MA
Background/Purpose: As the cost of genome-wide genotyping plummets, and biobanking efforts integrating medical records and genetics are rapidly expanding, many patients will have genotyping available…
Abstract Number: 201 • 2017 ACR/ARHP Annual Meeting
Computer Learning (artificial intelligence) to Create a Computer-Based Triage Tool Classifying Referrals As Inflammatory or Non-Inflammatory Requiring Only Patient Reported Information
Cindy Kim¹, Tanner Bohn², Charles X. Ling³, Nikhil Chopra⁴ and Janet E. Pope⁵, ¹Faculty of Medicine, University of Western Ontaro, London, ON, Canada, ²University of Western Ontario, London, ON, Canada, ³Computer Sciences, University of Western Ontario, London, ON, Canada, ⁴Rheumatology, Private Practice, London, ON, Canada, ⁵Department of Medicine, Division of Rheumatology, University of Western Ontario, St Joseph's Health Care, London, ON, Canada
Background/Purpose: To determine if a computer-based triage tool can accurately classify referrals as inflammatory or non-inflammatory using information obtained from the patient; not requiring assessment…
Abstract Number: 215 • 2017 ACR/ARHP Annual Meeting
Clinical Pharmacist As Part of the Interprofessional Team Improves Quality of Care in Patients with Rheumatic Disease
Jessica Farrell¹, Lee S. Shapiro¹ and Mitchell Miller², ¹The Center for Rheumatology, Albany, NY, ²Albany College of Pharmacy and Health Sciences, Albany, NY
Background/Purpose: Successful multidisciplinary models exist for the management of chronic diseases such as diabetes, cardiovascular disease, infectious diseases, kidney disease and psychiatric illnesses. A multidisciplinary…
Abstract Number: 234 • 2017 ACR/ARHP Annual Meeting
Impact of Arthritis Among Populations with Chronic Health Conditions in Rural Counties of the United States – 2015
Michael Boring¹, Louise Murphy², Jennifer M. Hootman³ and Yong Liu², ¹Arthritis Program, Centers for Disease Control and Prevention, Atlanta, GA, ²Division of Population Health, Centers for Disease Control and Prevention, Atlanta, GA, ³Centers for Disease Control and Prevention, Kennesaw, GA
Background/Purpose: US rural populations have well documented health disparities, including higher prevalence of chronic health conditions; however, arthritis prevalence among those with other chronic conditions…
Abstract Number: 249 • 2017 ACR/ARHP Annual Meeting
Where to Look for Uric Acid Crystals? Results from a Norwegian Ultrasound Study
Hilde B Hammer¹, Lars Karoliussen², Lene Terslev³, Espen A. Haavardsholm⁴, Tore K Kvien⁵ and Till Uhlig⁴, ¹Rheumatology, Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ²Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ³Copenhagen Center for Arthritis Research, Center for Rheumatology and Spine Diseases, Rigshospitalet, Denmark, Copenhagen, Denmark, ⁴Dept. of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway, ⁵On behalf of the NOR-DMARD registry, Oslo, Norway
Background/Purpose: Ultrasound (US) has received an increasing attention in detecting uric monosodium urate (MSU) deposits, and is included in the ACR/EULAR classification criteria for gout.…
Abstract Number: 250 • 2017 ACR/ARHP Annual Meeting
An Ultrasonographic Study for Investigating Relationships with the Signs of Uric Deposition and Bone Erosion in Patients with Hyperuricemia
Ikuko Tanaka¹, Takashi Kato², Motokazu Kai³, Kunikazu Ogawa³, Hisaji Oshima⁴ and Shigenori Tamaki⁵, ¹NAGOYA Rheumatology Clinic, Nagoya, Japan, ²Department of Radiology, National Center for Geratrics and Gerontology, Obu, Japan, ³Mie Rheumatology Clinic, Suzuka, Japan, ⁴Department of Connective Tissue Diseases, National Tokyo Medical Center, Tokyo, Japan, ⁵Nagoya Rheumatology Clinic, Nagoya, Japan
Background/Purpose: Joint ultrasonography (US) is a noninvasive examination that can evaluate arthritis and uric acid deposition at gout attacks. The purpose of this study was…
Abstract Number: 251 • 2017 ACR/ARHP Annual Meeting
Articular Cartilage of Knee and First MTP Joint Are the Preferred Sites of Urate Crystal Deposition in Asymptomatic Hyperuricemic Individuals
Danveer Bhadu¹, Siddharth K. Das², Urmila Dhakad³ and Archana Wakhlu⁴, ¹Rheumatology, ALL INDIA INSTITUTE OF MEDICAL SCIENCES, NEW DELHI, NEW DELHI, India, ²Rheumatology, Prof. and Head, Rheumatology, K.G. Medical University, Lucknow, Lucknow, India, ³Rheumatology, Asst Professor, K.G. Medical University, Lucknow, India, Lucknow, India, ⁴Radiology, Senior Resident, Lucknow, India
Background/Purpose: The prevalence of hyperuricemia ranges from 2.6% to 47.2% in various populations [1,2]. Ultrasound evidence of urate crystal deposition in the form of double…
Abstract Number: 293 • 2017 ACR/ARHP Annual Meeting
Expanded Therapeutic ACPA Utility for Different NET-Driven Human (Autoimmune) Diseases
Renato G.S. Chirivi^1,2, Jos W.G. van Rosmalen¹, Kostantinos Kambas³, Gonny Schmets¹, Hans Kalisvaart¹, Galina S. Bogatkevich⁴, Tim Shaw², Helmuth van Es² and Jos M.H. Raats^1,2, ¹ModiQuest BV, Oss, Netherlands, ²Citryll BV, Nijmegen, Netherlands, ³Laboratory of Molecular Hematology, Democritus University of Thrace, Alexandroupolis, Greece, ⁴Division of Rheumatology and Immunology, Department of Medicine, Medical University of South Carolina, Charleston, SC
Background/Purpose: Aberrant Neutrophil Extracellular Trap (NET) formation contributes to the induction and propagation of inflammation and plays a key role in causing tissue damage in…
Abstract Number: 308 • 2017 ACR/ARHP Annual Meeting
Frequency, Morbidity and Healthcare Utilization of Diffuse Idiopathic Skeletal Hyperostosis (DISH) Patients at a University Hospital
Maanas Tripathi¹, Divya Rajmohan², Cody Quirk³, Brooke Beckett³, Donseok Choi⁴, Neha Rich-Garg⁵ and Atul A. Deodhar⁴, ¹University of Miami, FL, Miami, FL, ²Oregon Health & Sciences University, Portland, OR, ³Radiology, Oregon Health & Science University, Portland, OR, ⁴Oregon Health & Science University, Portland, OR, ⁵Northwest Rheumatology Assoc., Portland, OR
Background/Purpose: DISH is a non-inflammatory condition affecting the spine, and characterized by ossification of paravertebral ligaments. DISH is traditionally considered asymptomatic, detected incidentally on spine…

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