Abstract Number: 2241 • ACR Convergence 2023
Guselkumab Efficacy in Active Psoriatic Arthritis Patients with or Without Hyperuricemia: Post-hoc Analysis of Two Phase 3, Randomized, Double-blind, Placebo-Controlled Studies
Background/Purpose: Patients (pts) with psoriasis (PsO) or PsA are at increased risk for developing gout; and hyperuricemia (HU) prevalence is higher in PsO/PsA pts than…Abstract Number: 2477 • ACR Convergence 2023
Anifrolumab Normalizes the Type I Interferon Signature in a Cohort of Patients with Type I Interferonopathies
Background/Purpose: Autoinflammatory Type I Interferonopathies (IFNopathies) include SAVI (STING-associated vasculopathy with onset in infancy), CANDLE/PRASS (Chronic atypical neutrophilic dermatosis, with lipodystrophy and elevated temperature), and…Abstract Number: 2505 • ACR Convergence 2023
Discovery of First-in-Class IRAK4 Scaffolding Inhibitors for the Treatment of Inflammatory Disorders
Background/Purpose: Interleukin-1 receptor-associated kinase 4 (IRAK4), is a key node that mediates inflammatory signaling in response to activation of toll-like receptor (TLR) and IL-1 receptor…Abstract Number: 2525 • ACR Convergence 2023
Comparing Patellar Tendon Characteristics Between Adults with and Without Knee Pain
Background/Purpose: Knee pain is one of the most common types of joint pain leading to disability, limited physical activity, and reduced quality of life. While…Abstract Number: 2563 • ACR Convergence 2023
Causal Associations Between Gut Microbiota and Rheumatic Diseases: A Mendelian Randomization Study
Background/Purpose: Gut microbiota has been increasingly recognized as important and novel targets for rheumatic diseases. However, previous studies mostly examined the associations, leaving causality largely…Abstract Number: 2600 • ACR Convergence 2023
Clonal Hematopoiesis Is Associated with Giant Cell Arteritis
Background/Purpose: Giant cell arteritis (GCA) is an age-related vasculitis of large and medium vessels. Prior population studies have identified an association between GCA and hematologic…Abstract Number: PP14 • ACR Convergence 2023
Putting Lived Experience into Action: Flipping the Script on Living with a Chronic Disease
Background/Purpose: Naomi was diagnosed with Juvenile Idiopathic Arthritis (JIA) at the age of 18, after enduring 3 years of misdiagnoses. Similarly, Natasha received a diagnosis…Abstract Number: 0089 • ACR Convergence 2022
Racial Disparities in Rheumatology Clinical Trials
Background/Purpose: Healthcare disparities exist in patients living with rheumatologic diseases. Factors contributing to disparities include age, sex, race, or sociodemographic variables, each playing a crucial…Abstract Number: 0118 • ACR Convergence 2022
Sex-Based Variations in Emergency Department Utilization by Persons with Inflammatory Arthritis Conditions
Background/Purpose: High quality ambulatory care provision should mitigate avoidable emergency department (ED) visits by persons with inflammatory arthritis (IA) conditions and address the unique realities…Abstract Number: 0119 • ACR Convergence 2022
Emergency Department Utilization by Persons with Inflammatory Arthritis Conditions Varies by Geographic Location of Residence
Background/Purpose: Rheumatology services in Canada are largely restricted to urban centres, resulting in significant access difficulties for residents of rural and remote locations. As a…Abstract Number: 0126 • ACR Convergence 2022
Should Arthrocentesis Be Attempted in the Symptomatic but Non-Effusive Knee?
Background/Purpose: Arthrocentesis of the painful but non-effusive knee is usually not undertaken due to a high arthrocentesis failure rate. We hypothesized that compression-assisted arthrocentesis of…Abstract Number: 0236 • ACR Convergence 2022
What Ultrasound Skills Can Be Learned Before Laying Hands on a Probe? Results of a Pilot Study of a Hybrid Online and in Person Curriculum to Teach Rheumatology Focused Knee Ultrasonography Skills to Internal Medicine Residents
Background/Purpose: Developing competence in musculoskeletal point of care ultrasound (MSK POCUS) involves mastery of 3 key domains: image acquisition, image interpretation, and incorporation of findings…Abstract Number: 0743 • ACR Convergence 2022
Home-Based Telehealth in Rheumatology: A Systematic Review & Narrative Synthesis
Background/Purpose: Home based telehealth (HBT) visits, where a patient is located at home with a remote provider, became common during the COVID-19 pandemic. Patients now…Abstract Number: 0973 • ACR Convergence 2022
Assessing Musculoskeletal Health Needs of Underserved Patients & Community Members Using a Community Based Participatory Research Approach
Background/Purpose: Musculoskeletal disorders are the most prevalent health conditions in the U.S. resulting in financial and social burdens, especially in underserved communities. There are also…Abstract Number: 1006 • ACR Convergence 2022
Impact of Uric Acid Levels on Clinical and Radiographic Characteristics in Psoriatic Arthritis and Response to Secukinumab: A Pooled “Post Hoc” Analysis from Five Phase 3 Studies
Background/Purpose: Hyperuricemia (HU), a common metabolic abnormality, may result in development of gout, which is an inflammatory arthritic condition1,2. Patients (pts) with psoriasis (PsO)/psoriatic arthritis…
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