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  • Abstract Number: 137 • 2012 ACR/ARHP Annual Meeting

    Monosodium Urate Crystals Inhibit Tenocyte Viability and Function: Implications for Periarticular Involvement in Chronic Gout

    Ashika Chhana1, Karen E. Callon1, Bregina Pool1, Dorit Naot1, Gregory Gamble2, Brendan Coleman3, Fiona M. McQueen4, Jillian Cornish1 and Nicola Dalbeth1, 1Medicine, University of Auckland, Auckland, New Zealand, 2Department of Medicine, University of Auckland, Auckland, New Zealand, 3Orthopedic Surgery, Middlemore Hospital, Auckland, New Zealand, 4Molecular Medicine and Pathology, University of Auckland, Auckland, New Zealand

    Background/Purpose: Recent advanced imaging studies have demonstrated that urate deposition in periarticular structures is common in gout. Urate deposition has been observed both adjacent to…
  • Abstract Number: 138 • 2012 ACR/ARHP Annual Meeting

    Evaluating Appropriate Use of Prophylactic Colchicine and Urate Lowering Therapy in Gout

    Michael George1, Sally W. Pullman-Mooar2 and H. Ralph Schumacher3, 1Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, 2Rheumatology, University of Pennsylvania and Philadelphia Veterans Hospital, Philadelphia, PA, 3Department of Medicine, University of Pennsylvania and VA Medical Center, Philadelphia, PA

    Background/Purpose: Colchicine is recommended to prevent gout flares in patients initiating and increasing uric acid lowering therapy until serum uric acid is ≤ 6 mg/dL.…
  • Abstract Number: 139 • 2012 ACR/ARHP Annual Meeting

    Lack of Effect of Supplemental Vitamin C On Serum Urate in Patients with Gout

    Lisa K. Stamp1, Christopher Frampton1, John L. O'Donnell2, Jill Drake3 and Peter T. Chapman4, 1Department of Medicine, University of Otago, Christchurch, Christchurch, New Zealand, 2Rheumatology Immunology & Allergy, Canterbury Health Laboratories, Christchurch, New Zealand, 3Rheumatology, Immunology and Allergy, Christchurch Hospital, Christchurch, New Zealand, 4Rheumatology, Immunology & Allergy, Christchurch Hospital, Christchurch, New Zealand

    Background/Purpose:   The key to effective long-term management of gout is sustained reduction of serum urate (SU) Methods: Patients with gout and a SU >0.36mmol/L…
  • Abstract Number: 141 • 2012 ACR/ARHP Annual Meeting

    Effectiveness of Prophylaxis with Anti-Gout Medications On Risk of Gout Attacks

    Tuhina Neogi1, Clara Chen2, Jingbo Niu3, Christine E. Chaisson4, David J. Hunter5, Hyon Choi6 and Yuqing Zhang7, 1Clinical Epidemiology, Boston University School of Medicine, Boston, MA, 2Boston University School of Public Health, Boston, MA, 3Boston University School of Medicine, Boston, MA, 4Arthritis Center, Boston University School of Public Health, Boston, MA, 5Rheumatology, Institute of Bone and Joint Research, Kolling Institute, University of Sydney, Sydney, Australia, 6Section of Rheumatology and the Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA, 7Clinical Epidemiology Unit, Boston University School of Medicine, Boston, MA

    Background/Purpose: While a few studies have examined colchicine's ability to prevent gout attacks, NSAIDs have not been formally studied in this regard, despite use of…
  • Abstract Number: 142 • 2012 ACR/ARHP Annual Meeting

    Efficacy of Canakinumab Versus Triamcinolone Acetonide According to Multiple Gouty Arthritis-Related Health Outcomes Measures

    Ari Gnanasakthy1, Andrew Sarkin2, Rachel Lale2, Kyle Choi2 and Jan D. Hirsch3, 1Novartis Pharmaceuticals Corporation, East Hanover, NJ, 2Health Services Research Center, University of California, San Diego, CA, 3Skaggs School of Pharmacy & Pharmaceutical Sciences, University of California, San Diego, CA

    Background/Purpose: Canakinumab (CAN), a selective, fully human, anti-IL-1β monoclonal antibody, may be a potential therapeutic option for treating acute gout attacks and delaying new attacks…
  • Abstract Number: 143 • 2012 ACR/ARHP Annual Meeting

    Proposed Gout Treatment Guidelines and Meeting Serum Urate and Flare Goals

    Jasvinder A. Singh1, David Hagerty2, Chris Storgard3, Robert Mischler4 and Robert Morlock4, 1Department of Medicine, University of Alabama, Tuscaloosa, AL, 2Medical, Ardea Bioscience, San Diego, CA, 34939 Directors Place, Ardea Bioscience, San Diego, CA, 4Ardea Bioscience, San Diego, CA

    Background/Purpose: Although gout is a relatively common condition, treatment is often not ideal with many patients continuing to experience multiple flares and some developing complications…
  • Abstract Number: 144 • 2012 ACR/ARHP Annual Meeting

    Long-Term Safety of Canakinumab in Patients with Gouty Arthritis

    Alexander So1, Reike Alten2, H. Ralph Schumacher3, Mark Bloch4, Thomas Bardin5, Markus R. John6, Gerhard Krammer6, Jan Michael Nebesky6, Aiyang Tao7 and Naomi Schlesinger8, 1Rheumatology, CHUV, Univ of Lausanne, Lausanne, Switzerland, 2Charité Univ Medicine, Berlin, Germany, 3Department of Medicine, University of Pennsylvania and VA Medical Center, Philadelphia, PA, 4Holdsworth House Medical Practice, Sydney, Australia, 5Rheumatology, Hôpital Lariboisière, Paris, France, 6Novartis Pharma AG, Basel, Switzerland, 7Novartis Pharmaceuticals Corporation, East Hanover, NJ, 8UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ

    Background/Purpose: Gouty arthritis (GA) is a chronic inflammatory disease. Targeting the inflammatory pathway through IL-1β inhibition with canakinumab (CAN) may provide significant long-term benefits.  CAN…
  • Abstract Number: 145 • 2012 ACR/ARHP Annual Meeting

    Prevalence of Non-Gout Arthritis in Patients with Gout: Not As Sparing As Previously Thought

    Fernando Perez-Ruiz1 and Ana M. Herrero-Beites2, 1Servicio de Reumatologia, Hospital Universitario Cruces, Baracaldo, Spain, 2Physical Medicine Division, Hospital de Gorliz, Gorliz, Spain

    Background/Purpose: the presence of other chronic inflammatory disease has been historically and academically thought to be “protective” conditions for the development of gout. Objective: to…
  • Abstract Number: 146 • 2012 ACR/ARHP Annual Meeting

    The Treatment of Acute Gouty Arthritis in Complex Hospitalized Patients with Anakinra

    Mary Bach1, Jane Park1, Pradipta Ghosh1, Peter A. Simkin2 and Gregory C. Gardner3, 1Rheumatology, University of Washington, Seattle, WA, 2Div of Rheumatology, University of Washington, Seattle, WA, 3Medicine/Rheumatology, University of Washington, Seattle, WA

    Background/Purpose: The management of acute crystal-induced arthritis in the hospital setting may be a difficult clinical problem due to co-morbidities that limit the use of…
  • Abstract Number: 101 • 2012 ACR/ARHP Annual Meeting

    Kidney Function and the Risk of Incident Gout in A Population-Based Cohort of Adults: Atherosclerosis Risk in Communities Study

    Mara McAdams DeMarco1, Anna Kottgen2, Andrew Law3, Janet W. Maynard4, Josef Coresh1 and Alan N. Baer5, 1Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD, 2Renal Division, University Hospital Freiburg, Freiburg, Germany, 3Epidemiology, Johns Hopkins, Baltimore, MD, 4Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD, 5Division of Rheumatology, Johns Hopkins University School of Medicine, Baltimore, MD

    Background/Purpose:  The 1-year cumulative incidence of gout in patients with new onset end stage renal disease is 5% and rises to 15% by 5 years,…
  • Abstract Number: 0077 • ACR Convergence 2025

    Transformer-based multi-omics study identifies important role of glycine, serine and threonine metabolism pathway in rheumatoid arthritis complicated by anemia

    Fanxin zeng1, Jianxin Huang2, Yuanli Wei3, Dongmei Wang3, Jianghua Chen4, Congcong Jian1, Xiaoting Zhu5, Shilin Li5, Jie Zhang5, Tingting Wang3, Caizhen Liu6, Lingli Wei3, Jing Gao3, Jing Zhu7, Qinghua Zou8 and Jianhong Wu3, 1Departmant of Clinical Research Center, Sichuan Clinical Research Center for Medical Imaging, Dazhou Central Hospital; Medical School, Sichuan University of Arts and Sciences; School of Basic Medical Science, Chengdu University of Traditional Chinese Medicine, Dazhou, China (People's Republic), 2Institute of Basic Medicine and Forensic Medicine, North Sichuan Medical College, Nanchong, China (People's Republic), 3Department of Rheumatology and Immunology, Dazhou Central Hospital, Dazhou, China (People's Republic), 4Dazhou Vocational College of Chinese Medicine, Dazhou, China (People's Republic), 5Departmant of Clinical Research Center, Sichuan Clinical Research Center for Medical Imaging, Dazhou Central Hospital, Dazhou, China (People's Republic), 6Department of Rheumatology and Immunology, Dazhou Central Hospital, Dazhou, 7Department of Rheumatology and Immunology, Sichuan Provincial People's Hospital, Chengdu, China (People's Republic), 8Department of Rheumatology and Immunology, First Affiliated Hospital of Army Medical University, Chongqing, China (People's Republic)

    Background/Purpose: Anemia is a prevalent hematologic complication of rheumatoid arthritis (RA) that exacerbates the disease process and severely impacts clinical performance and treatment strategies. We…
  • Abstract Number: 0082 • ACR Convergence 2025

    IBI3011, a Humanized anti-IL1RAP Monoclonal Antibody, Inhibits IL1, IL33, IL36-driven Inflammation Pathway, and Attenuates Inflammation in Preclinical Inflammatory Disease Model

    Hongling Tian, Lidan Liang, Chenjuan Zhu, Bin Li, Lei Cao, Meng Ni, Fan Chen, Zhimin Zhang, Min Wu, Tong Liu, Jinyang Li, Yao Xiong, Li Li, Shuaixiang Zhou, Enhong Zhong and Huizhong Xiong, Innovent Biologics (Suzhou) Co., Ltd., Suzhou, Jiangsu, China (People's Republic)

    Background/Purpose: Interleukin 1 receptor accessory protein (IL1RAP) serves as a co-receptor that forms receptor complexes with IL1R1, ST2, and IL36R and mediates signaling pathways triggered…
  • Abstract Number: 0171 • ACR Convergence 2025

    The Association Between Short-Term Trajectory Of Atmospheric Particulate Matter 10 (PM10) Concentration And Hyperuricemia

    Sunggun Lee1, Minyoung Her1, Seong-HO Kim1, Yong-Gil Kim2 and Ji Seon Oh2, 1Department of Internal Medicine, Haeundae Paik Hospital, Inje University College of Medicine, Busan, Republic of Korea, 2Division of Rheumatology, Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, South Korea, Seoul, Republic of Korea

    Background/Purpose: The association between high atmospheric particulate matter concentration and gout flare has been reported1, but the causality and mechanism of this association remain unknown.…
  • Abstract Number: 0219 • ACR Convergence 2025

    Increased Engagement With the RISE Registry Clinician Dashboard Is Associated With Improving Performance on Some but Not All Rheumatology Quality Measures

    Jing Li1, Jessica Fitzpatrick2, Jinoos Yazdany2 and gabriela Schmajuk3, 1University of California, San Francisco, San Francisco, CA, 2UCSF, San Francisco, CA, 3University of California, San Francisco, and San Francisco Veterans Affairs Medical Center, San Francisco, CA

    Background/Purpose: Previous studies have shown that quality measure performance tends to improve after practices join the ACR’s Rheumatology Informatics System for Effectiveness (RISE) registry, but…
  • Abstract Number: 0220 • ACR Convergence 2025

    National Implementation of a Medication Safety Dashboard to Improve HLA-B*58:01 Testing Among Allopurinol Users in the Veterans Health Administration

    Alissa Becerril1, Jing Li2, Cherish Wilson3, Gary Tarasovsky4, Abimbola Fadairo-Azinge5, Mary Whooley4 and gabriela Schmajuk6, 1UCSF, san francisco, CA, 2University of California, San Francisco, San Francisco, CA, 3UCSF / SFVA, San Francisco, CA, 4SFVA, San Francisco, 5UCSF, San Francisco, 6University of California, San Francisco, and San Francisco Veterans Affairs Medical Center, San Francisco, CA

    Background/Purpose: Allopurinol can cause life-threatening severe cutaneous adverse reactions, especially in patients who carry the HLA-B58:01 allele. Because this allele is more common among Southeast…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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