Abstract Number: 2960 • 2014 ACR/ARHP Annual Meeting
Urate Genetic Loci and the Risk of Incident Cases of Confirmed Gout in Two Prospective Cohort Studies
Background: Gout is the most common inflammatory arthritis and is caused by hyperuricemia. The Global Urate Genetics Consortium (GUGC) has recently validated 28 SNP associations…Abstract Number: 2962 • 2014 ACR/ARHP Annual Meeting
Association of the Toll-like Receptor 4 (TLR4) Gene with Gout
Background/Purpose: Gout results from innate immune response to monosodium urate (MSU) crystals that form in the context of supersaturation of urate. Identification of genetic risk…Abstract Number: 2963 • 2014 ACR/ARHP Annual Meeting
The URAT1 Uric Acid Transporter Is Important in Uric Acid Homeostasis and Its Activity May be Altered in Gout Patients and in Drug-Induced Hyperuricemia
Background/Purpose: Gout results from chronic hyperuricemia. Most gout patients exhibit an increased renal reabsorption of uric acid which leads to elevated levels of serum uric…Abstract Number: 2964 • 2014 ACR/ARHP Annual Meeting
Association Analysis of Apolipoprotein B and Very Low-Density Lipoprotein with Hyperuricemia and Gout
Background/Purpose: Gout results from an innate immune response to monosodium urate (MSU) crystals deposited in joints. Increased very low-density lipoprotein (VLDL) has been associated with…Abstract Number: 2322 • 2014 ACR/ARHP Annual Meeting
Aim for Better Gout Control: A Retrospective Analysis of Preventable Hospital Admissions for Gout
Background/Purpose: ACR/EULAR guidelines have been published on the management of gout. Despite these guidelines, many patients with gout suffer recurrent flares and hospitalizations resulting in…Abstract Number: 2179 • 2014 ACR/ARHP Annual Meeting
The Monocyte-Phagocyte System in Gout: Enhanced Inflammasome Activity and Expansion of CD14++CD16+ Monocytes in Patients with Gout
Background/Purpose: The central role of the monocyte-macrophage system in gout has been highlighted during the last years. Macrophages initiate the inflammatory response to monosodium urate…Abstract Number: 2148 • 2014 ACR/ARHP Annual Meeting
Dual Energy CT Scanning: Variable Sensitivity for Gout in Non-Tophaceous and Tophaceous Disease and in Individual Erosions
Background/Purpose: Dual energy computed tomography (DECT) is emerging as a diagnostic tool for gout, but its sensitivity has not been established. We assessed the sensitivity…Abstract Number: 2114 • 2014 ACR/ARHP Annual Meeting
Comorbidity Characteristics of Patients Starting First-Line Acute Gout Agents – Colchicine, NSAID, and Corticosteroids
Comorbidity Characteristics of Patients Starting First-Line Acute Gout Agents - Colchicine, NSAID, and CorticosteroidsBackground/Purpose: There is a remarkable, increasing disease burden of gout and its…Abstract Number: 2121 • 2014 ACR/ARHP Annual Meeting
Real-World Cost Comparison of Urate Lowering Therapies in Patients with Gout and Moderate to Severe Chronic Kidney Disease
Background/Purpose Gout flare prevention relies heavily on urate-lowering therapies (ULT) such as allopurinol (ALP) and febuxostat (FBX) but clinical decision-making in patients with moderate to…Abstract Number: 2125 • 2014 ACR/ARHP Annual Meeting
Burden of Illness in Refractory Gouty Arthritis: A One-Year Prospective Multinational, Observational Study
Background/Purpose: Refractory gouty arthritis (RGA) is a condition characterized by appearance of recurrent flares and contraindication, intolerance, or lack of efficacy to first-line anti-inflammatory therapy…Abstract Number: 2003 • 2014 ACR/ARHP Annual Meeting
Pilot Study of a Web-Based Module on Gout
Background/Purpose: The majority of internal medicine trainees complete residency with little exposure to rheumatology. We aimed to create a validated, self-directed, web-based, core curriculum in…Abstract Number: 1874 • 2014 ACR/ARHP Annual Meeting
Obesity Paradox in Recurrent Gout – a Metrological Clarification and Remedy
Background/Purpose: Obesity is a strong risk factor of incident gout, but previous research showed no such association with recurrent gout among gout patients. These paradoxical…Abstract Number: 1873 • 2014 ACR/ARHP Annual Meeting
Food Sources of Protein and Risk of Incident Gout in the Singapore Chinese Health Study
Background/Purpose: The Health Professional Follow up Study in Caucasian men showed that intakes of meat and seafood increased risk of gout, while dairy products, especially…Abstract Number: 1872 • 2014 ACR/ARHP Annual Meeting
Gout in Older Adult
Background/Purpose: To evaluate whether traditional and genetic risk factors in middle-aged members of a longitudinal population-based cohort predict the onset of gout in older age.…Abstract Number: 1808 • 2014 ACR/ARHP Annual Meeting
Role of HLA-B*5801 Genetic Testing and a Safety Programme When Initiating Allopurinol Therapy for Chronic Gout Management: A Cost-Effectiveness Analysis
Background/Purpose To conduct a cost-effectiveness analysis from a health system perspective of various strategies in managing chronic gout to mitigate risk of allopurinol-induced Stevens-Johnson Syndrome…
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