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  • Abstract Number: 0358 • ACR Convergence 2022

    Long-term Safety and Efficacy of Voclosporin in Hispanic and Latino Patients with Lupus Nephritis

    Ellen M. Ginzler1, Amit Saxena2, Victoria Bal3, Vanessa Birardi4 and Henry Leher4, 1SUNY Downstate Health Sciences University, Department of Medicine, Brooklyn, NY, 2NYU School of Medicine, New York, NY, 3Aurinia Pharmaceuticals, Inc., Victoria, BC, Canada, 4Aurinia Pharmaceuticals Inc, Rockville, MD

    Background/Purpose: The AURORA 1 study demonstrated that addition of voclosporin to MMF and low-dose steroids significantly increased complete renal response rates at 52 weeks, with…
  • Abstract Number: 1653 • ACR Convergence 2022

    Voclosporin for Lupus Nephritis: Assessment of Long-Term Safety and Efficacy Including Renal Outcome over Three Years of Treatment in the Phase 3 AURORA 1 and AURORA 2 Studies

    Cristina Arriens1, Samir Parikh2, Lucy Hodge3, Chris Mela4 and Henry Leher5, 1Oklahoma Medical Research Foundation, Oklahoma City, OK, 2The Ohio State University, Columbus, OH, 3Aurinia Pharmaceuticals, Seattle, WA, 4Aurinia Pharmaceuticals, Inc., Victoria, BC, Canada, 5Aurinia Pharmaceuticals Inc, Rockville, MD

    Background/Purpose: In the Phase 3 AURORA 1 study, the addition of voclosporin to mycophenolate mofetil (MMF) and low-dose steroids led to significant reductions in proteinuria…
  • Abstract Number: 1425 • ACR Convergence 2021

    Voclosporin for Lupus Nephritis: Interim Analysis of the AURORA 2 Extension Study

    Amit Saxena1, Christopher Mela2 and Antonia Coeshall3, 1NYU School of Medicine, New York, NY, 2Aurinia Pharmaceuticals Inc., Victoria, BC, Canada, 3Aurinia Pharmaceuticals Inc., Rockville

    Background/Purpose: Voclosporin, a novel calcineurin inhibitor (CNI), has been tested successfully in 2 pivotal trials in adult patients with lupus nephritis (LN). Previously reported results…
  • Abstract Number: 1751 • ACR Convergence 2021

    Voclosporin Is Effective in Achieving Complete Renal Response Across Lupus Nephritis Biopsy Classes: Pooled Data from the AURA-LV and AURORA 1 Trials

    Anca Askanase1, Simrat Randhawa2, Laura Lisk3 and Paola Mina-Osorio4, 1Columbia University Medical Center, New York, NY, 2Aurinia Pharmaceuticals Inc., Seattle, WA, 3Aurinia Pharmaceuticals Inc., Victoria, ON, Canada, 4Aurinia Pharmaceuticals Inc., New York, NY

    Background/Purpose: Voclosporin is a novel calcineurin inhibitor recently approved for the treatment of adult patients with active lupus nephritis in combination with background immunosuppressive therapy.…
  • Abstract Number: 1752 • ACR Convergence 2021

    Efficacy of Voclosporin in Recent Onset Lupus Nephritis

    Meggan Mackay1, Matt Truman2, Nicole England2, Vanessa Birardi3 and Paola Mina-Osorio4, 1Feinstein Institutes for Medical Research, Manhasset, NY, 2Aurinia Pharmaceuticals Inc., Victoria, BC, Canada, 3Aurinia Pharmaceuticals Inc, Rockville, MD, 4Aurinia Pharmaceuticals Inc., New York, NY

    Background/Purpose: Voclosporin is a novel calcineurin inhibitor recently approved for the treatment of adults with active lupus nephritis (LN) in combination with background immunosuppressive therapy.…
  • Abstract Number: 0862 • ACR Convergence 2020

    Voclosporin Does Not Decrease Mycophenolic Acid Concentrations in Patients with SLE

    Teun van Gelder1, Robert Huizinga2, Neil Solomons2 and Laura Lisk3, 1Leiden University Medical Centre, Leiden, Zuid-Holland, Netherlands, 2Aurinia Pharmaceuticals, Victoria, BC, Canada, 3Aurinia Pharmaceuticals Inc., Victoria, BC, Canada

    Background/Purpose: Voclosporin (VCS) is a novel calcineurin inhibitor, structurally similar to cyclosporine A (CsA). In a Phase 3 clinical trial in patients with active lupus…
  • Abstract Number: 1843 • ACR Convergence 2020

    Integrated Efficacy of the AURORA 1 and AURA-LV Trials Confirms Voclosporin Rapid Proteinurea Reduction in the Presence of Low-Dose Steroids

    Ellen M Ginzler1, Joshua Kaplan2, Laura Lisk3, Ray Federico4, Neil Solomons5 and Robert Huizinga5, 1SUNY Downstate Health Sciences University, Brooklyn, 2Rutgers University, New Brunswick, NJ, 3Aurinia Pharmaceuticals Inc., Victoria, BC, Canada, 4Aurinia Pharmaceuticals, Inc., Victoria, Canada, 5Aurinia Pharmaceuticals, Victoria, BC, Canada

    Background/Purpose: Voclosporin (VCS) is a novel calcineurin inhibitor (CNI) with a favorable metabolic profile and a consistent predictable dose response potentially eliminating the need for…
  • Abstract Number: 885 • 2017 ACR/ARHP Annual Meeting

    48-Week Complete Remission By Ethnic, Sex and Age Subgroups in Patients with Active Lupus Nephritis Treated with Voclosporin

    David Wofsy1, David A. Isenberg2, Frédéric A. Houssiau3, Mary Anne Dooley4, Neil Solomons5 and Simrat Randhawa6, 1Rheumatology, UCSF, San Francisco, CA, 2Centre for Rheumatology Research, Division of Medicine, University College London, London, United Kingdom, 3Rheumatology, Pôle de Maladies Rhumatismales, Université catholique de Louvain, Brussels, Belgium, 4UNC Kidney Centre, Chapel Hill, NC, 5Aurinia Pharmaceuticals Inc., Victoria, BC, Canada, 6Medical Affairs, Aurinia Pharmaceuticals, Victoria, BC, Canada

    Background/Purpose: Voclosporin (VCS) is a novel CNI with a favorable metabolic profile, no observed effect on electrolytes, and a predictable dose response potentially eliminating the…
  • Abstract Number: 5L • 2016 ACR/ARHP Annual Meeting

    Speed of Remission with the Use of Voclosporin, MMF and Low Dose Steroids: Results of a Global Lupus Nephritis Study

    Mary Anne Dooley1, William Pendergraft III2, Ellen M. Ginzler3, Nancy J. Olsen4, James Tumlin5, Brad H. Rovin6, Frédéric A. Houssiau7, David Wofsy8, David A. Isenberg9, Neil Solomons10, Robert Huizinga11 and AURA Study Group, 1Dooley Rheumatology, Chapel Hill Doctors, Chapel Hill, NC, 2Kidney Center, University of North Carolina, Chapel Hill, NC, 3Rheumatology, SUNY Downstate Medical Center, Brooklyn, NY, 4Medicine/Rheumatology, Penn State Hershey Medical Center, Hershey, PA, 5Nephrology, University of Tennessee College of Medicine, Chattanooga, TN, 6Ohio State University Medical Center, Columbus, OH, 7Rheumatology, Pôle de Maladies Rhumatismales, Université catholique de Louvain, Brussels, Belgium, 8Rheumatology, University of California, San Francisco, San Francisco, CA, 9Centre for Rheumatology Research, University College Hospital London, UK, London, United Kingdom, 10Aurinia Pharmaceuticals Inc., Victoria, BC, Canada, 11Clinical Affairs, Aurinia Pharmaceuticals Inc., Victoria, BC, Canada

    Background/Purpose: Voclosporin (VCS) is a novel CNI intended for use in the treatment of autoimmune diseases such as lupus nephritis. VCS’s unique structure allows for…
  • Abstract Number: 0188 • ACR Convergence 2025

    Investigating Canadians’ information needs related to lupus: A Google Trends analysis of online search query data

    Taylor Williamson1, Emily Shantz1, Susan Elliott1, Christine Sperling2, Karen H. Costenbader3 and May Choi4, 1University of Waterloo, Waterloo, Canada, 2None, Calgary, Canada, 3Harvard Medical School and Brigham and Women's Hospital, Boston, MA, 4University of Calgary, Calgary, AB, Canada

    Background/Purpose: A lack of knowledge surrounding SLE has been identified as a main challenge for patients, particularly those seeking a diagnosis or recently diagnosed. Subsequently,…
  • Abstract Number: 0667 • ACR Convergence 2025

    Retrospective Chart Audit Reveals Gaps in Steroid Tapering and Use of ACR Guideline-Recommended Regimens in LN

    Sawyer May1, Lynn Price1 and Ryan Rex2, 1Spherix Global Insights, Exton, PA, 2Spherix Global Insights, Chester Springs, PA

    Background/Purpose: In May 2025, ACR released updated recommendations for the management of LN2. Notably, since the previous guidelines update in 2012, the FDA has approved…
  • Abstract Number: 1038 • ACR Convergence 2025

    Real-World Immunosuppressant Treatment Patterns in Lupus Nephritis: A Retrospective Claims Database Analysis in the United States

    Anisha Patel1, Alexandra Miller1, Lisa Lindsay1, Danny Sheinson1, Zhiyu Xia1, William Pendergraft1 and Maria Dall'Era2, 1Genentech, Inc., South San Francisco, CA, 2Division of Rheumatology, University of California, San Francisco, CA

    Background/Purpose: LN is a severe manifestation of SLE requiring intensive management. We aimed to characterize real-world treatment patterns in newly diagnosed patients with LN within…
  • Abstract Number: 1044 • ACR Convergence 2025

    Analysis of Medicare and Medicaid Utilization and Expenditure of Newly Approved Biologics for Systemic Lupus Erythematosus Patients in the United States

    Gunjan Rana1, Mansi Mehta1 and Joanne Cunha2, 1Saint Vincent Hospital, Worcester, MA, 2BROWN MEDICINE, BROWN UNIVERSITY, Riverside, RI

    Background/Purpose: Hydroxychloroquine is a cornerstone in the treatment of Systemic Lupus Erythematosus (SLE), while corticosteroids and immunosuppressive agents are employed for moderate to severe disease…
  • Abstract Number: 1547 • ACR Convergence 2025

    Anifrolumab In Systemic Lupus Erythematosus With Renal Involvement: National Multicenter Registry In Clinical Practice

    Vanesa Calvo-Río1, Carmen Secada-Gómez1, Blanca Garcia-Magallon2, Deseada Palma-Sanchez3, Andrea García-Valle4, Irati Urionaguena Onaindia5, Adrián Mayo-Juanatey6, Paúl Hernández Velasco7, GUILLERMO GONZALEZ ARRIBAS8, Ana Pareja-Martínez9, Montserrat Corteguera10, Guillen Sada Urmeneta11, Paz Collado Ramos12, Jose Luis Tandaipan13, Juan Roberto Miguelez Sanchez14 and Ricardo Blanco1, 1Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain, 2Rheumatology. Hospital Universitario Puerta de Hierro, Madrid, Spain, 3Rheumatology. Hospital Rafael Méndez, Lorca, Murcia, Spain, 4Rheumatology. Hospital General Río Carrión, Palencia, Castilla y Leon, Spain, 5Rheumatology.Hospital Galdakao, Vizcaya, Pais Vasco, Spain, 6Hospital Universitario Doctor Peset, Valencia, Comunidad Valenciana, Spain, 7Nephrology, Hospital Universitario 12 de Octubre, Madrid. Spain, Madrid, Madrid, Spain, 8Facultativo especialista, PALMA DE MALLORCA, Galicia, Spain, 9Rheumatology. Hospital Universitario Infanta Leonor, Madrid, Madrid, Spain, 10Rheumatology. Complejo Asistencial de Ávila, Ávila, Castilla y Leon, Spain, 11Rheumatology. Hospital Reina Sofía, Tudela, Navarra, Spain, 12Department of Rheumatology, Hospital Universitario Severo Ochoa, Madrid, Spain,, MADRID, Madrid, Spain, 13Rheumatology. Hospital Universitario de la Santa Creu i Sant Pau, Barcelona, Spain, 14Department of Rheumatology, Hospital Universtiario de Móstoles, Madrid, Spain, Madrid, Madrid, Spain

    Background/Purpose: Lupus Nephritis (LN) is a serious complication of systemic lupus erythematosus (SLE), occurring in up to 50% of patients. Currently, Anifrolumab (ANI) is approved…
  • Abstract Number: 2575 • ACR Convergence 2025

    Influenza and COVID-19 Vaccination Uptake Among Women with Systemic Rheumatic Diseases in New York City Assessed Between 2022 and 2024

    Yongjay Kim1, Sandhya Kannayiram2, Amaya Smole3, Lucy Masto4, Neha Nagpal5, Naiva Manuela Piatchou Donfack5, Deanna Jannat-Khah5, Lisa Mandl5, Caroline Siegel5, Sarah Lieber5, Michael Lockshin5, Lisa Sammaritano5 and Medha Barbhaiya5, 1Hospital for Special Surgery, Englewood Cliffs, NJ, 2Hospital for Special Surgery, Weill Cornell Medicine, New York, 3Hospital for Special Surgery, Brooklyn, NY, 4Hospital for Special Surgery, San Francisco, CA, 5Hospital for Special Surgery, New York, NY

    Background/Purpose: Women with systemic rheumatic diseases (SRDs), and particularly those on immunosuppressive medications, are at increased risk for serious infections such as influenza and COVID-19.…
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Embargo Policy

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM CT on October 25. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

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