ACR Convergence 2026 Archives - ACR Meeting Abstracts

Abstract Number: 2511

S100 Proteins Identify Active Disease in Juvenile Localized Scleroderma and Outperform Traditional Biomarkers
Abstract Number: 1047

SAB05, a CD40-Targeted Antibody-Drug Conjugate of a Highly Potent Glucocorticoid, Delivers Cell-Selective Immunosuppression and Disease Control with Steroid-Sparing Safety in Models of Autoimmune and Inflammatory Disease
Abstract Number: 0467

Safety and effectiveness of 265 combinations of targeted therapies in immune mediated inflammatory diseases : data from the COMBATT registry
Abstract Number: 0587

Safety and Effectiveness of Tumor Necrosis Factor Inhibitors Initiated Before Versus After 2 Years Old in Children with Non-Systemic Juvenile Idiopathic Arthritis Using the CARRA Registry
Abstract Number: 0225

Safety and Efficacy of Anti-CD19 Allogenic Chimeric Antigen Receptor (CAR) T Cell Therapy Zugocabtagene Geleucel (zugo-cel) in Patients with Refractory Systemic Sclerosis
Abstract Number: 0206

Safety and efficacy of avacopan in ANCA-associated vasculitis: a single-center experience
Abstract Number: 0280

Safety and Efficacy of AZD0120 (GC012F), a Dual-Targeting CD19/BCMA CAR-T Cell Therapy, in Refractory Systemic Lupus Erythematosus: Phase 1/2 Interim Results
Abstract Number: 2223

Safety and Efficacy of CD19-BAFF Bicephali Multi-target CAR-T Cell Therapy in Refractory Systemic Lupus Erythematosus: A Clinical Study
Abstract Number: 2224

Safety and Efficacy of Enpatoran in Lupus: Results Up To 109 Weeks of the Phase II WILLOW Long-Term Extension Study
Abstract Number: 0281

Safety and Efficacy of GC012F/AZD0120, an Autologous CD19/BCMA Dual-Targeting FasTCAR T Cell Therapy, in Refractory Systemic Lupus Erythematosus: 96-Week Long-term Follow-up
Abstract Number: 1240

Safety and Efficacy of Subcutaneous Ianalumab (VAY736) Post-B Cell Recovery in Patients with Systemic Lupus Erythematosus: End-of-Study Results from a Phase 2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study
Abstract Number: 0226

Safety and Efficacy of Topical Sodium Metabisulfite for the Treatment of Calcinosis in Patients with Systemic Sclerosis
Abstract Number: 2765

Safety and Efficacy of Zoster Vaccination in Patients with Rheumatic Diseases: A Systematic Review and Meta-Analysis
Abstract Number: 2640

Safety and Preliminary Efficacy of Allogeneic CD19 CAR-NK (CNTY101) in Patients with Autoimmune Disease: Data of the Phase I/II CARAMEL Basket Trial
Abstract Number: 0876

Safety and Preliminary Efficacy of Allogeneic Dual-Target CD19/BCMA CAR-T in Refractory Systemic Lupus Erythematosus: First Report of a Phase I/IIa Trial
Abstract Number: 2682

Safety of Bispecific Antibodies in Patients With Autoimmune Disease and Hematologic Malignancies: A Real-World Propensity-Matched Study
Abstract Number: 2793

Safety of Corticosteroid Injection for Carpal Tunnel Syndrome in Rheumatoid Arthritis
Abstract Number: 2602

Safety of First-Line Disease-Modifying Antirheumatic Drugs in Idiopathic Inflammatory Myopathy
Abstract Number: 1358

Safety of Guselkumab in Participants With Active Psoriatic Arthritis: Pooled Results From Four Phase 3, Randomized, Placebo-Controlled Trials
Abstract Number: 0207

Safety Outcomes Among Patients With Polymyalgia Rheumatica Treated With Interleukin 6 Inhibitors
Abstract Number: 1392

Safety profile of ianalumab in Sjögren’s disease: Observations from the pooled results of the phase 3 trials NEPTUNUS-1 and NEPTUNUS-2 up to 52 weeks.
Abstract Number: 1635

Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of DWP212525, an Oral Small-Molecule Inhibitor Targeting JAK and Tec Family Kinases, after Single-Dose in Healthy Adults Volunteers.
Abstract Number: 1393

Salivary flow as a marker of glandular reserve in Sjögren’s disease
Abstract Number: 1793

Salivary Flow as a Non-Invasive Biomarker of Periodontal Disease in Patients with Rheumatic Diseases
Abstract Number: 1856

Salivary Gland Ultrasonography Severity Reflects Progressive Exocrine Dysfunction in Sjögren’s Disease
Abstract Number: 0435

Salivary Gland Ultrasound Complements Clinical Risk Features in Sjögren’s Disease Malignancy Evaluation
Abstract Number: 0665

Salvage Therapy in Anti-MDA5+ Dermatomyositis Associated Rapidly Progressive Interstitial Lung Disease: A Hypoxemia-Defined Window for Rituximab
Abstract Number: 2273

Same Diagnosis, Different Risk: A National Analysis of Sex Based Outcomes in SLE Associated Pericarditis
Abstract Number: 0507

Same Treatment, Different Outcomes: At Initiation of First Advanced Therapy in Early RA, Mental Health Predicts Worse Treatment Response at 6-12 Months
Abstract Number: 0050

SAP+CD8+ T cells mediate the transition of SLAMF6+ memory CD8 T cells into granzyme expressing effectors in Lupus Nephritis.
Abstract Number: 2794

Sarcoidosis in Rheumatology Practice: Early initiation of immunosuppresives may prevent relapses during long term follow-up
Abstract Number: 1359

Sarcopenia in Radiographic Axial Spondyloarthritis: Beyond Disease-Specific Clinical Factors
Abstract Number: 0187

Sarilumab in Refractory and/or Glucocorticoid-Dependent Polymyalgia Rheumatica Beyond the SAPHYR Trial: Real-World Outcomes from a Multicenter Spanish Cohort
Abstract Number: 1669

SARS-CoV-2 Infection and Rheumatoid Arthritis-Associated Autoantibody Testing and Positivity: A Retrospective Cohort Study From a National Reference Laboratory
Abstract Number: 1909

SAT1 loss-of-function drives lupus-like autoimmunity through polyamine depletion and macrophage mitochondrial reprogramming
Abstract Number: 2005

Scar associated Macrophages Localize to Non-sclerotic Glomeruli in Low-Proteinuric Class III Lupus Nephritis
Abstract Number: 1394

SCOLYSS: Score of Lymphoma Risk in Sjögren’s Syndrome
Abstract Number: 0244

Screen-Detected Interstitial Lung Disease on High-Resolution Computed Tomography Scan of the Chest in Systemic Sclerosis: Prevalence, Clinical Features, Biomarker Profile, and One-Year Progression
Abstract Number: 1893

Secukinumab Delays Time to Relapse in Patients with Polymyalgia Rheumatica After Treatment Discontinuation: Results from the Treatment-Free Follow-up Period in REPLENISH
Abstract Number: 1636

Secukinumab Demonstrates Consistent Clinical Efficacy in Patients with Psoriatic Arthritis and Elevated BMI and Associated Comorbidities
Abstract Number: 2124

Secukinumab in patients with polymyalgia rheumatica: Subgroup analyses of Week 52 results of a Phase 3, multicentre, randomised, double-blind, placebo-controlled trial (REPLENISH)
Abstract Number: 1145

Secukinumab Reduces Glucocorticoid Associated Toxicity in Patients with Recently Relapsed Polymyalgia Rheumatica: Results of Phase 3 REPLENISH Trial
Abstract Number: 0282

Secular Trends in Glucocorticoid Exposure and Treat to Target Outcomes in an Asian Active SLE Cohort
Abstract Number: 2348

Secular Trends in the Incidence of Psoriatic Disease: A Comparative Analysis of the Pre- and Post-COVID-19 Pandemic Period
Abstract Number: 1637

Seeing an Alternative: The Role of Leflunomide in Autoimmune Eye Disease
Abstract Number: 1199

Segmental loss of motility drives reduced small bowel function in Systemic Sclerosis: a pilot MR Enterography study
Abstract Number: 0283

Select Serum Immune Mediators are Associated with Hydroxychloroquine Treatment and SLE Classification Progression in a Nested Cohort of At-Risk Study Participants in the Study of Antimalarials in Incomplete Lupus Erythematosus (SMILE) Trial
Abstract Number: 1112

Selective Immunoproteasome Inhibition by Novel Once-Weekly Oral Agents Achieves Superior Suppression of Autoimmune Responses with Enhanced Safety Margin Over Subcutaneous　Zetomipzomib in Multiple Preclinical Models
Abstract Number: 0088

Selective SIK2 inhibition suppresses inflammation and disease in mouse and human models of rheumatoid arthritis
Abstract Number: 1808

Self Reported Dietary Patterns and Symptom Perception in Systemic Lupus Erythematosus
Abstract Number: 1809

Self-Determination Theory Predictors of Physical Activity in Adults with Knee Replacement
Abstract Number: 1543

Self-Efficacy in Pregnant and Breastfeeding Women with Rheumatic and Musculoskeletal Diseases: An International Cross-Sectional Pilot Study
Abstract Number: 1920

Self-Supervised Foundation Models for ANA Image Representation and Phenotype Discovery
Abstract Number: 2054

Sequential Intra-Articular Delivery of High-Capacity Adenovirus Expressing IL-1Ra from an NFκB-Inducible Promoter (HCAd-NFκB-IL-1Ra) Improves Therapeutic Efficacy in a Murine Model of Post-Traumatic Osteoarthritis
Abstract Number: 1200

Serial CA 15-3 and KL-6, but not SP-D, correlate with pulmonary function, quantitative HRCT severity and disease activity in patients with systemic sclerosis-associated interstitial lung disease
Abstract Number: 0954

Serial Quantitative Changes in Anti-Scl-70 Autoantibodies Are Associated with Lung Function Decline in Systemic Sclerosis
Abstract Number: 1764

Serious Infection Risk in SLE Is Highest in Lupus Nephritis and Associated With Glucocorticoid Burden: A Population-Based Cohort Study
Abstract Number: 1395

Serious infections in primary Sjögren syndrome and systemic lupus erythematosus: association with treatment exposure and disease group.
Abstract Number: 0336

Serologically Active Clinically Quiescent Lupus Is Associated With Increased Left Ventricular Mass
Abstract Number: 2817

Serum Biomarkers C3M and ARGS Distinguish Multidimensional Pain Subgroups in Knee Osteoarthritis in the IMI-APPROACH Study
Abstract Number: 1098

Serum Cytokine and Chemokine Profiling Reveals Distinct Immune Programs in Sjögren’s Disease
Abstract Number: 0154

Serum Cytokine Profile During Pregnancy in Patients with Systemic Lupus Erythematosus, Rheumatoid Arthritis, and Antiphospholipid Syndrome
Abstract Number: 0508

Serum Cytokines and Chemokines in the Risk Stratification of Rheumatoid Arthritis-Associated Interstitial Lung Disease
Abstract Number: 0037

Serum KL-6 and ICAM-1 correlate with percent predicted forced vital capacity at baseline but not ongoing disease progression in individuals with systemic sclerosis associated interstitial lung disease
Abstract Number: 2187

Serum proteins reflecting vascular processes associate with interstitial lung disease development in patients with systemic sclerosis
Abstract Number: 0137

Serum proteomic heterogeneity highlights early sensing and autophagy programs in autoantibody-positive preclinical lupus
Abstract Number: 0992

Serum Proteomic Profiling Reveals Distinct Biological Signatures Linked to Clinical Phenotypes and Patient-Reported Outcomes in Systemic Sclerosis
Abstract Number: 2830

Serum Proteomic Signatures Reflect Synovial Pathotypes and Predict Treatment Response in Early Rheumatoid Arthritis
Abstract Number: 1201

Serum Type I Interferon Activation as a Predictor of Diffuse Subclinical Myocardial Involvement in Systemic Sclerosis
Abstract Number: 1970

Serum Type I Interferon Activity As A Biomarker Of Morbimortality In Systemic Sclerosis Independent Of Cutaneous Subset
Abstract Number: 2766

Serum Uric Acid Inversely Associated with Age-Related Macular Degeneration
Abstract Number: 2654

Serum Uric Acid Target Attainment and Prevalence of Major Adverse Cardiovascular Events in Gout and Normouricemia: A Nationally Representative Cross-Sectional Analysis
Abstract Number: 1971

Severe lower gastrointestinal disease in Systemic Sclerosis is associated with distinct vascular and neuroimmune proteomic signatures
Abstract Number: 1360

Severity of MASLD on MRI-PDFF in Psoriatic Disease: Does Sex Matter?
Abstract Number: 2349

Sex Differences in Axial Spondyloarthritis Are Not Attenuated by HLA-B27 Positivity: A 10-year Analysis of the DESIR Cohort
Abstract Number: 0075

Sex Differences in Cellular Immune Profiles in Psoriatic Arthritis
Abstract Number: 0640

Sex Differences in Coping Efficacy in Individuals with Symptomatic Knee Osteoarthritis Referred for Total Knee Arthroplasty
Abstract Number: 0400

Sex- and Gender-Based Analysis of the Effectiveness of Advanced Therapies in Psoriatic Arthritis (SAGE-PsA) study: Baseline Differences in Socio-demographics, PsA feature, Treatment and Co-morbidities
Abstract Number: 2125

Sex-Based Differences in Clinical Outcomes Among Patients With Giant Cell Arteritis: A U.S. Population Based Study
Abstract Number: 2309

Sex-related Differences in Efficacy and Safety of Advanced Therapies in Psoriatis Arthritis Randomized Clinical Trials: An Updated Systematic Literature Review and Meta-Analysis for the GRAPPA Treatment Guidelines
Abstract Number: 1074

Sex-Related Differences in Tryptophan and Glutathione Metabolism in Late-Stage Osteoarthritis
Abstract Number: 0076

Sex-Specific Biomarkers in the Transition to PsA: Longitudinal Metabolomic Analyses
Abstract Number: 1361

Sex, Uveitis, and HLA-B27 as Independent Predictors of Diagnostic Delay in Axial Spondyloarthritis: Data From the Brazilian Registry of Spondyloarthritis (RBE)
Abstract Number: 0604

Sexual Dysfunction and Body Image Perception Among Patients with Systemic Sclerosis and Inflammatory Myopathy
Abstract Number: 0605

Sexual Health and Body Image Perception in Men with Rheumatic Diseases: A Cross-Sectional Study
Abstract Number: 0064

SGLT2 Inhibition Is Associated with a Distinct Ferroptosis-Related Biomarker Profile in Active Lupus Nephritis
Abstract Number: 2225

SGLT2 Inhibitor Exposure and Glucocorticoid Re-Initiation in Patients With Systemic Lupus Erythematosus
Abstract Number: 2560

SGLT2 Inhibitor Use Is Associated With Lower Fragility Fracture Risk Than DPP-4 Inhibitor Use in Older Women With Diabetes: A Propensity-Matched TriNetX Study
Abstract Number: 1169

SGLT2 Inhibitors and Major Adverse Cardiovascular Events in ANCA-Associated Vasculitis: A Retrospective Propensity Score-Matched Cohort Study
Abstract Number: 1867

SGLT2 Inhibitors and Renal Outcomes in Non-Diabetic Lupus Nephritis: A Propensity Score-Matched Real-World Cohort Study with Immunosuppressive Regimen Adjustment
Abstract Number: 1713

Shared Goals, Different Frames: Patient and Physician Perspectives on Reproductive Health Counseling in Systemic Lupus Erythematosus
Abstract Number: 2025

Shared molecular signatures of treatment non-response across rheumatoid arthritis therapeutic classes reveal candidate targets for drug repurposing
Abstract Number: 0102

Shared synovial and immune-cell serum signatures are associated with methotrexate-modulated clinical improvement in Early Rheumatoid Arthritis
Abstract Number: 1113

SHARP: Super High-Resolution Microscopy of ANA Reactivity Patterns
Abstract Number: 0828

Shifting Tides: Temporal Trends and Changing Causes of Death in ANCA-Associated Vasculitis Mortality in the United States, 1999-2024 – A CDC WONDER Analysis
Abstract Number: 2411

Short-Course Oral R-2487 Induces Durable Clinical Responses and Coordinated Regulatory Immune Remodeling in Rheumatoid Arthritis
Abstract Number: 0337

Short-Term Exposure To Air Quality Index And Risk Of Emergency Department Visits For Systemic Lupus Erythematosus
Abstract Number: 1202

Short-Term Exposure to Ambient Air Pollution and Raynaud’s Phenomenon Severity in Systemic Sclerosis
Abstract Number: 2146

Short-Term Safety and Efficacy of the CD20×CD3 T-Cell Engager CND261 in ANCA-Associated Vasculitis
Abstract Number: 0666

Sialic Acid-binding Ig-like Lectin 1: A Serological Biomarker for Interstitial Lung Disease in Idiopathic Inflammatory Myopathies
Abstract Number: 1733

Significantly Higher Documentation Quality Through Pre-visit Computer-Assisted History-Taking for Inflammatory Rheumatic Disease Screening: A Randomized Pilot Study
Abstract Number: 2833

Single cell annotation with B-CellAnnoTator reveals plasma cell subsets associated with clinical outcome in lupus nephritis
Abstract Number: 1329

Single Nucleus RNA Sequencing of Methylprednisolone Effects Reveals Biomarkers in PsA Synovial Lining Fibroblasts
Abstract Number: 0155

Single-cell Analysis Reveals Treatment-driven Remodeling of B cell States and Therapeutic Target Expression in ANCA-associated Vasculitis
Abstract Number: 2092

Single-cell characterization of plasma cells in SSc-ILD reveals distinct functional state
Abstract Number: 0115

Single-cell metabolic modeling identifies inositol phosphate and lysophosphatidic acid metabolic pathways associated with synovial inflammation in osteoarthritis
Abstract Number: 1945

Single-cell profiling of peripheral B cells reveals disease-associated naïve B-cell states and altered inflammatory programs in IgA vasculitis
Abstract Number: 0108

Single-Cell RNA-Sequencing and Spatial Transcriptomics of Synovial Biopsies From Patients with Oligoarticular and Polyarticular Juvenile Idiopathic Arthritis
Abstract Number: 2887

Single-cell spatial transcriptomics identifies heterogeneous fibroblast and macrophage populations within compartment-specific immune-stromal niches in giant cell arteritis temporal arteries
Abstract Number: 2226

Single-Cell Spatial Transcriptomics on Baseline and Repeat Kidney Biopsies Reveal Greater Tissue-Resident B Cell Niche Disruption with CD19-CAR T-Cell Therapy than with Conventional Immunosuppression in Lupus Nephritis
Abstract Number: 0051

Single-cell Transcriptomic Profiling Reveals Distinct Neutrophil States and Functional Features in Systemic Lupus Erythematosus
Abstract Number: 0103

Single-Cell Transcriptomics Identifies Monocyte Antigen Presentation and Adiposity-Associated Costimulatory Programs in Rheumatoid Arthritis
Abstract Number: 0109

Single-Cell-Derived Fibroblast Signature for Diagnosis and Disease Activity Assessment Pediatric Localized Scleroderma
Abstract Number: 2059

Single-Nucleus RNA Sequencing of Skeletal Muscle Reveals Interferon-Driven Myonuclear Damage and a Pro-Fibrotic Microenvironment in Dermatomyositis
Abstract Number: 1146

Single-Organ Vasculitis: Clinical Characteristics and Classification
Abstract Number: 1638

Site-Specific Mucosal Candidiasis Associated With Bimekizumab, Secukinumab, and Guselkumab: A Pharmacosurveillance Analysis of the FDA Adverse Event Reporting System (FAERS)
Abstract Number: 2375

Sjögren’s Disease in the Arab Middle East and North Africa Populations: A Scoping Review of Epidemiologic and Diagnostic Characteristics
Abstract Number: 2376

Sjögren’s Syndrome and Cutaneous Manifestations: A High-Risk Phenotype for Systemic Involvement
Abstract Number: 1288

Skin Activity Is Associated with Greater Fatigue and Poorer Quality of Life in People with Cutaneous Lupus Erythematosus With or Without System Lupus Erythematosus
Abstract Number: 1461

Skin Temperatures of the Hand Six Meridians and Five Transport Points are Elevated in Rheumatoid Arthritis
Abstract Number: 0245

Skin Trajectory and Clinical Features Associated with Five-Year Survival in Diffuse Cutaneous Systemic Sclerosis
Abstract Number: 2093

SLC15A4 Inhibitor, OD-002, Selectively Blocks Pathogenic B Cell Responses
Abstract Number: 1765

Sleep Disorder-Related Adverse Events Associated with Janus Kinase Inhibitors: A Pharmacovigilance Analysis of the FDA Adverse Event Reporting System (FAERS)
Abstract Number: 1544

Sleep Disorders Predict Worse Real-World Outcomes in Autoimmune Disease Despite Biologic Therapy: A Large Propensity-Matched Cohort Study
Abstract Number: 1545

Sleep Quality Assessed by the Pittsburgh Sleep Quality Index and Correlates of Poor Sleep in Patients with Autoimmune Rheumatic Diseases: Beyond Disease Activity
Abstract Number: 0338

SLERPI Probability Index Can Predict Flare Risk At Three Years In a Real-world German Population
Abstract Number: 0016

Small-Molecule Inhibitors of TNF Reduce Pro-inflammatory Disease Activity while Retaining TNFR2 Signaling, Which Preserves the Suppressive Capacity of Regulatory T Cells and Promotes Immune Tolerance
Abstract Number: 1065

Smoldering Neutrophil-Mediated Inflammation in pSLE: Persistent NETs Despite Standard Therapy
Abstract Number: 0052

snRNAseq of NZM2410 Mouse Hearts Reveals a Coordinated Immune-Stromal Cross-talk that Results in Fibrosis and Loss of Cardiomyocytes
Abstract Number: 0776

Social Determinants of Health in Psoriatic Arthritis: The Impact of What We Don’t Measure
Abstract Number: 2767

Social isolation and outcomes in rheumatoid arthritis: a retrospective cohort study
Abstract Number: 2711

Social Risk Factor Phenotypes Associated with Missed Appointments Among Patients with Rheumatoid Arthritis
Abstract Number: 2768

Sociodemographic and Clinical Characteristics of Early- and Late-Onset Gout Among U.S. Adults: NHANES 2011-2018
Abstract Number: 1766

Sociodemographic and Clinical Factors Associated with Non-Attendance at Rheumatology Outpatient Appointments
Abstract Number: 2712

Socioeconomic, Symptomatic, and Administrative Burdens Compound Lupus Trial Participation Challenges: Findings from the 2026 Lupus Clinical Investigators Network (LuCIN) Annual Survey
Abstract Number: 1655

Sodium-Glucose Cotransporter 2 Inhibitors and Serum Urate Reduction in Patients with Gout and Type 2 Diabetes
Abstract Number: 2930

Somatic Genetic Variation with Mosaic Loss of Y Chromosome and Interstitial Lung Disease, Cardiovascular Events, and Mortality in Men with Rheumatoid Arthritis
Abstract Number: 1602

Somatosensory Profiling in Patients with Idiopathic Inflammatory Myopathies
Abstract Number: 1928

Spatial and Functional Characterization of SPP1+ Macrophages in Pre-RA and RA Synovium
Abstract Number: 0124

Spatial and Transcriptomic Characterization of the Gouty Tophus as a Structured Inflammatory Microenvironment: Evidence for SPP1 ⁺ Macrophage-Fibroblast Crosstalk and Local Complement Activation
Abstract Number: 2026

Spatial dissection of synovial pathotype biology in rheumatoid arthritis reveals coordinated lymphoid, stromal and vascular programs driving lymphoid aggregate organization and a machine learning-based blood-detectable pathotype signature
Abstract Number: 1972

Spatial Insights into Melanocyte Niches in Salt-and-Pepper Dyspigmentation of Systemic Sclerosis
Abstract Number: 0017

Spatial Mapping of Synovial Immune Architecture Identifies an Enriched Tfh Niche in Rheumatoid Arthritis
Abstract Number: 1973

Spatial Multiomics Decode Scleroderma Renal Crisis in the Kidney
Abstract Number: 0038

Spatial Orchestration of Skin Fibrosis by a CD8 T cell-Myofibroblast Axis
Abstract Number: 2027

Spatial transcriptomics of B cell targeting T-cell engager therapy reveals extrafollicular niche collapse and a pretreatment fibrogenic-stromal signature in multidrug-resistant RA
Abstract Number: 0089

Spatial transcriptomics of rheumatoid arthritis synovium reveals compartment-specific remodeling by csDMARD and anti-TNF therapy
Abstract Number: 1066

Spatial Transcriptomics Reveals a Continuum of Tertiary Lymphoid Structure States in Juvenile Idiopathic Arthritis Synovium
Abstract Number: 1067

Spatial Transcriptomics Reveals Diffuse Th17/IL-17 Synovial Inflammation Outside Tertiary Lymphoid Structures in Refractory Pediatric Arthritis with a Heterozygous STAT5B Loss-of-Function Variant
Abstract Number: 1094

Spatial Transcriptomics Reveals Distinct Patterns of Tissue Remodeling Following Interferon Receptor Blockade in Dermatomyositis and Cutaneous Lupus Erythematosus
Abstract Number: 1068

Spatial Transcriptomics Reveals Divergent Coagulation and Immune Programs in CpG induced MAS- and Perforin-deficient HLH Liver Injury
Abstract Number: 1095

Spatial Transcriptomics Reveals Glandular Cell Involvement in the Pathophysiology of Sjögren’s Disease
Abstract Number: 2912

Spatial transcriptomics reveals mechanism of autoimmunity driven by internalized autoantibodies
Abstract Number: 2041

Spatial Transcriptomics reveals Rosnilimab-induced immune and stromal niche remodeling in Rheumatoid Arthritis
Abstract Number: 1075

Spatial transcriptomics reveals severity-associated cellular remodeling in injury synovitis
Abstract Number: 1670

Spondyloarthritis may be an Underrecognized Cause of Persistent Musculoskeletal Pain following Lyme Disease
Abstract Number: 1147

Spontaneous Remission of Giant Cell Arteritis: A Case Report and Scoping Review
Abstract Number: 1060

Sputum Biomarker Profiles in Smokers That Differentially Predict Progression to Clinical RA
Abstract Number: 1203

SSc-Associated Myopathy in Clinical Practice Guidelines: A Systematic Review Revealing Critical Evidence Gaps and Methodological Heterogeneity
Abstract Number: 2655

SSGJ-613 for the treatment of acute gout flares: results from a randomized, double-blind, double-dummy, active-controlled phase 3 trial
Abstract Number: 0188

Stakeholder-informed priority setting for UK giant cell arteritis guideline development: a national mixed-methods study
Abstract Number: 0553

Standardizing Adrenal Insufficiency Education to Improve Patient Safety: A Pediatric Rheumatology QI Initiative
Abstract Number: 2512

Standardizing and Improving the Transition from Pediatric to Adult Rheumatology Care: A Collaborative Longitudinal Program
Abstract Number: 2274

Statins May Not be Associated with a Reduction in Primary Cardiovascular Events in Patients with Systemic Lupus Erythematosus
Abstract Number: 2656

Steatotic Liver Disease Phenotypes and Incident Gout Across the Metabolic-Alcohol Spectrum: Analysis Based on Three Population-Based Databases
Abstract Number: 1933

STING-STAT3-SOX18 Axis Drives EndMT and Epigenetic Reprogramming in SAVI Lung Fibrosis
Abstract Number: 1148

Stool Microbiome Composition and Functional Profiling in Large-Vessel Vasculitis
Abstract Number: 1810

Strategies for Physical Activity Following Total Knee Arthroplasty: Associations with Daily Step Count
Abstract Number: 2513

Stratifying Risk of Uveitis Among Patients with Oligoarticular or Polyarticular Juvenile Idiopathic Arthritis
Abstract Number: 1871

Stress cardiac MRI phenotyping across systemic diseases: ischemic burden and prognostic implications
Abstract Number: 1817

Stress Cardiovascular MRI Findings in Patients with Antiphospholipid Syndrome
Abstract Number: 2975

Stromal Cells Express IL-6 within Critical Tissue Niches in IgG4-Related Disease
Abstract Number: 2350

Structural Damage of the Spine has a Modest Effect on Spinal Mobility Over 2 Years in Axial Spondyloarthritis
Abstract Number: 0890

Structural Lesions Of The SI Joints In Early Axial SpA Versus Non-axial SpA Chronic Back Pain: 2-year Results From The SPondyloArthritis Caught Early Cohort
Abstract Number: 1011

Structured Illumination Microscopy Demonstrates Increased Blood-Brain-Barrier Permeability in Murine Neuropsychiatric Lupus
Abstract Number: 1462

Study Of Neuropeptides In Rheumatoid Arthritis And Their Role In The Inflammatory Response
Abstract Number: 0863

Subclinical Cardiac Involvement in Antiphospholipid Antibody-Positive Patients: Distinct Echocardiographic Phenotypes in Primary and SLE-Associated Disease
Abstract Number: 0509

Subclinical Inflammation by Power Doppler Ultrasound in Rheumatoid Arthritis in Recent Clinical Remission: Baseline Analysis of a Prospective Cohort
Abstract Number: 0125

Subclinical inflammation in patients with Familial Mediterranean Fever with well-controlled disease
Abstract Number: 1069

Subclinical Monosodium Urate Deposition in Pediatric Hyperuricemia: Association With ABCG2 Variants
Abstract Number: 1204

Subclinical Myocardial Involvement in Systemic Sclerosis: Associations with Nailfold Capillaroscopy Patterns and Individual Microvascular Features
Abstract Number: 2802

Subclinical ocular microvascular involvement in Primary Antiphospholipid Syndrome and antiphospholipid antibodies carriers
Abstract Number: 2275

Subclinical Right Ventricular Dysfunction Is Associated With Prior Disease Flare Requiring Hospitalization in Clinically Stable Systemic Lupus Erythematosus
Abstract Number: 0877

Subcutaneous RXIM002, a Targeted Lipid Nanoparticle Circular RNA Therapy, for In Vivo Anti-CD19 Chimeric Antigen Receptor T-Cell Generation in Effector Memory T cells and Terminally Differentiated Effector T cells for Treatment of Refractory Systemic Lupus Erythematosus
Abstract Number: 0468

Subcutaneous Tocilizumab versus Abatacept in Rheumatoid Arthritis with inadequate response to TNFis: results of the SUNSTAR head-to-head, multicentre, open-label, randomised superiority trial
Abstract Number: 2847

Subsequent Autoimmune Disease in Children Exposed in Utero to Maternal Anti-SSA/Ro Antibodies is Associated with Manifestations of Neonatal Lupus and HLA-DR3 Genotype
Abstract Number: 0829

Summed Omega-3 Derived Lipid Mediator Combination Predicts Progression to Clinical Rheumatoid Arthritis in an At-Risk Anti-Citrullinated Protein Antibody (ACPA) Positive Population
Abstract Number: 1603

Suppression of Paraoxonase-1 Enzyme Activity in Patients with Idiopathic Inflammatory Myopathies Predicts Diagnosis of Malignancy
Abstract Number: 0401

Survival in Patients with Axial Spondyloarthritis and Cancer
Abstract Number: 1330

Survival Of Biological Therapy According To Sex And HLA-B27 Positivity In Patients With Spondyloarthritis
Abstract Number: 0402

Survival Outcomes in Patients with Psoriasis or Psoriatic Arthritis and Concomitant Cancer
Abstract Number: 1664

Sustained Improvement in HLA-B*5801 Testing Rates Prior to Allopurinol Initiation in High-Risk Patient Populations After an Order Menu Revision
Abstract Number: 2917

Sustained Protection Against SARS-CoV-2 Infection After COVID-19 Vaccination in Chronic Inflammatory Rheumatic Diseases
Abstract Number: 2310

Sustained Real-World Treatment Persistence of Bimekizumab After IL-17A Inhibitor Failure in Psoriatic Arthritis
Abstract Number: 2311

Switch Versus Swap After First Biologic or Targeted Synthetic Disease-Modifying Antirheumatic Drug in Axial Spondyloarthritis: A Meta-analysis
Abstract Number: 2147

Switching From Mepolizumab to Benralizumab After Glucocorticoid-Free Remission in EGPA: A Single-Center Observational Study
Abstract Number: 0053

Syk Signaling as a Central Immunothrombotic Hub in Antiphospholipid Syndrome
Abstract Number: 0403

Symptom Phenotype, Misdiagnosis Pathways, and Stage-Specific Diagnostic Delay in a Real-World Spondyloarthritis Cohort
Abstract Number: 2450

Synovial Fluid Aspiration and Cellularity in Real World Clinical Care
Abstract Number: 1061

Synovial Fluid Signatures of Lymphocytic Tissue Inflammation in Rheumatoid Arthritis Synovium.
Abstract Number: 1842

Synovial Histology in CPPD Disease and the Impact of Therapy on Synovial Inflammation: Interim Results of a Phase II Randomized Trial
Abstract Number: 1463

Synovial inflammation is concordant with DAS28-ESR but not RAPID3 in patients with rheumatoid arthritis
Abstract Number: 0916

Synovial Neutrophilic Inflammation Defines a Clinically Distinct Endotype of Early Rheumatoid Arthritis Associated with Poor Early Outcomes
Abstract Number: 0917

Synovial Tissue-Resident Macrophages Drive Immune Complex-Mediated Arthritis Through a RasGRP4-IL-1β Axis
Abstract Number: 0404

Systematic Underreporting of Sacroiliac Abnormalities on Routine Abdominal CT in Axial Spondyloarthritis: A Longitudinal Workflow Analysis
Abstract Number: 0699

Systemic Autoantibodies Do Not Independently Predict Outcomes in Familial Mediterranean Fever, Whereas Inflammatory Comorbidities Do
Abstract Number: 0777

Systemic Connective Tissue Diseases and Heart Failure Mortality: A Nationwide Age-Period-Cohort Analysis in Older Adults
Abstract Number: 0700

Systemic Immunosuppressive Medication Use and Racial Differences in Treatment Patterns Among Patients With Sarcoidosis
Abstract Number: 2276

Systemic Lupus Erythematosus and Antiphospholipid Antibody Syndrome as Risk Factors for Stroke in Young Patients: Analysis of the National Inpatient Sample
Abstract Number: 2006

Systemic Lupus Erythematosus, Mixed Connective Tissue Disease, and Sjogren’s Disease, All Characterized by Autoantibodies Targeting RNA-binding Proteins, Comprise a Group of Systemic Interferonopathies
Abstract Number: 2188

Systemic Sclerosis in Singapore and United States Cohorts: Investigating Serological Differences and Increased Rate of Pulmonary Restriction in Asians
Abstract Number: 0246

Systemic Sclerosis Induced by Immune Checkpoint Inhibitors from the Canadian Research Group of Rheumatology in Immuno-Oncology (CanRio): A Case Series
Abstract Number: 1974

Systemic sclerosis patients with different Scleroderma Clinical Trial Consortium Activity Index (SCTC-AI) levels display distinct transcriptomic and cellular signatures
Abstract Number: 2189

Systemic Sclerosis Wounds and Zinc Deficiency
Abstract Number: 1241

Systemic Treatment Patterns in Systemic Lupus Erythematosus (SLE): Associations with Disease Severity and Organ-Specific Activity Across 5 Registries in the Lupus Federated Data Network (LupusNet)
Abstract Number: 2960

Systemic Versus Local Corticosteroid Injection for Frozen Shoulder: Staged Randomized Pilot Trials