Date: Friday, November 6, 2020
Session Type: Poster Session A
Session Time: 9:00AM-11:00AM
Background/Purpose: The aim of this study is to explore the link between the severity of the joint and entheses involvement in psoriatic arthritis (PsA) using musculoskeletal ultrasound (US).
Methods: PsA patients from 2 centers in the Psoriatic Arthritis- International Database (PsArt-ID) (n=126) underwent an ultrasound assessment of 46 joints and 12 large entheses. The correlation between joint and enthesitis scores on the US was analyzed in addition to the clinical indices versus the US.
Results: Fifty-six of the 126 patients (44.4%) were male and the mean (SD) age was 54.8 (14.6) years. The mean PsA duration was 7.6 (8.3) years. Greyscale (GS) synovitis score for the joints was moderately correlated with the total enthesitis score (r=0.410, p< 0.001) (Table). The Global Outcome Measure in Rheumatology in Clinical Trials-European League Against Rheumatism Synovitis Score (GLOESS) score was also found in correlation with the total enthesitis score (r=0.400, p< 0.001) (Table). The link between the US and clinical examination findings only showed a poor correlation between swollen joint counts (SJC) and joint-US scores (r=0.298, p=0.001 for GLOESS). Assessment of the entheses on US showed a poor-moderate correlation between the entheseal damage scores and tender joint counts (TJC) (r=0.217, p= 0.018) and SJC (r=0.326, p= p< 0.001). In terms of the clinical examination and activity parameters, none of the clinical parameters and acute phase reactants were correlated to Leeds Enthesitis Index.
Conclusion: Our study showed a link between the severity of the sonographic findings in the joints and the entheses. The link between these two anatomical structures supports the synovio-entheseal complex theory.
To cite this abstract in AMA style:Ayan G, Tinazzi I, Bakirci S, Gazel U, Solmaz D, Kalyoncu U, Aydin S. The Link Between Joints and Entheses in Psoriatic Arthritis: An Ultrasound Study Supporting the Synovio-entheseal Complex Theory [abstract]. Arthritis Rheumatol. 2020; 72 (suppl 10). https://acrabstracts.org/abstract/the-link-between-joints-and-entheses-in-psoriatic-arthritis-an-ultrasound-study-supporting-the-synovio-entheseal-complex-theory/. Accessed January 19, 2021.
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