ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 234

The Decrease in Prescription of Anti-Osteoporotic Drugs Has No Impact on Hip Fracture Incidence

Karine Briot1, Milka Maravic2 and Christian Roux3, 1Cochin Hospital, Paris Descartes University, Paris, France, 2Hopital Leopold Bellan, Paris, France, 3Paris Descartes University, Cochin Hospital, Paris, France

Meeting: 2014 ACR/ARHP Annual Meeting

Keywords: , ,

Session Information

Title: Osteoporosis and Metabolic Bone Disease - Clinical Aspects and Pathogenesis: Osteoporosis: Pathogenesis, Epidemiology and Diagnosis

Session Type: Abstract Submissions (ACR)

Background/Purpose

Controversies exist about the change in hip fracture incidence among countries. In France, we previously showed that the incidence of hip fractures decreased in both genders, especially in the elderly from 2002 to 2008 in parallel with availability of bone densitometry and effective antiosteoporotic treatments. However these prescriptions are decreasing, since 2009 (1), and recent studies show declining of osteoporosis management after fragility fractures. The aim of this study was to assess the incidence of hip fractures in men and women aged 60 years and over, from 2008 to 2013 in France.

Methods

Data were drawn from the French Hospital National Database which includes all hospitalizations. Hospital data for hip fractures between 2002 and 2013 were numbered and the incidence rates per 1,000,000 adjusted on age (60-74; 74-84, and ≥ 85 years), and gender was calculated using the data of the French population.

Results

The number of hip fractures increased in women (+5%; from 49,287 in 2002 to 50,215 in 2013) and in men (+22%, from 12,716 to 15,482 in 2013). Between 2002 and 2013, the French population increased by 21 and 29% in women and in men. Incidence of hip fractures over 60 years decreased by -14% in women (6,929 and 5,987 per million in 2002 and 2013, respectively) and a slight decrease of -1%was observed in men (2,344 and 2,316 per million in 2002 and 2013, respectively). An age-specific incidence decrease was also confirmed, in particular, in the elderly in both genders (≥ 85 years) with a decrease of -29% in women and -24% in men (p<0.00001).

Conclusion

Over the last 12 years, the incidence of hip fractures decreased in France in women and men aged over 60 years. This decrease is particularly important in the elderly in both genders. This is observed in parallel with the decrease in prescription of antiosteoporotic treatments. Further studies are needed to assess potential changes in hip fractures risk factors during the last decade.

Reference:

1. Svedbom et al. Osteoporosis in the European Union: a compendium of country-specific reports. Arch Osteoporos. 2013; 8: 137

Disclosure:

K. Briot,
None;

M. Maravic,
None;

C. Roux,
None.

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