ACR Meeting Abstracts

ACR Meeting Abstracts

  • Meetings
    • ACR Convergence 2024
    • ACR Convergence 2023
    • 2023 ACR/ARP PRSYM
    • ACR Convergence 2022
    • ACR Convergence 2021
    • ACR Convergence 2020
    • 2020 ACR/ARP PRSYM
    • 2019 ACR/ARP Annual Meeting
    • 2018-2009 Meetings
    • Download Abstracts
  • Keyword Index
  • Advanced Search
  • Your Favorites
    • Favorites
    • Login
    • View and print all favorites
    • Clear all your favorites
  • ACR Meetings

Abstract Number: 186

The Association Between Low Back Pain and Radiographic Features: A Systematic Review with Meta-Analysis

Joachim Raastad1, Michael Reiman2, Remy Coeytaux2, Leila Ledbetter3 and Adam P. Goode2, 1Physical Therapy, Bergen University College, Bergen, Norway, 2Community and Family Medicine, Duke University, Durham, NC, 3Medical Center Library, Duke University, Durahm, NC

Meeting: 2014 ACR/ARHP Annual Meeting

Keywords: Low back pain, meta-analysis and radiography

  • Tweet
  • Email
  • Print
Session Information

Title: Orthopedics, Low Back Pain and Rehabilitation

Session Type: Abstract Submissions (ACR)

Background/Purpose: Low back pain (LBP) is a prevalent condition. Plain film radiography is a commonly used imaging technique for this condition. Radiographic features (RF) such as disc space narrowing (DSN), osteophytes, spondylosis, endplate sclerosis, spondylolisthesis and facet joint osteoarthritis have all been debated as potential pain generators in the lumbar spine. The aim of this study is to: 1) determine the association between LBP and lumbar spine RF in both community and occupation-based groups; and 2) to determine if there are differences in these associations between these two groups.

Methods: A systematic electronic search of PubMed, EMBASE, CINAHL and Cochrane was conducted with keywords related to LBP and lumbar spine RFs. The search was restricted from inception of each respective database to April 2014. Inclusion criteria consisted of observational studies of adults (≥18 years) with and without non-specific LBP. Studies were excluded if they investigated LBP related to infection, malignancy or rheumatologic nature or were conducted in cadavers. Quality assessment was conducted with the Item Bank for Assessment of Risk of Bias and Precision for Observational Studies of Interventions or Exposures. Random effect models were used for all pooled analyses with associations represented by odds ratios (OR) and 95% confidence intervals (95% CI). Statistical heterogeneity was indicated with an I2 value >50%. 

Results: Twenty-eight (22 community-based and 6 occupation-based) studies met the eligibility criteria consisting of 26,107 subjects. A significant, positive association was found between DSN and LBP that did not differ (p=0.22) between community (OR=1.47 ((95% CI 1.36-1.58)) and occupation-based studies (OR=1.76 ((95% CI 1.34 -2.33)). No significant statistical heterogeneity was present in either estimate (I2=0.0%). A significant association was found between spondylolisthesis and LBP in occupation-based studies (OR=2.21 ((95% CI 1.44 – 3.39)) that differed significantly (p<0.01) from community based studies (OR=1.12 ((95% CI 1.03 – 1.23)). These individual estimates were also homogeneous (I2<1.0%). The association between other radiographic features was modest (i.e., spondylosis and osteophytes) or non-significant (i.e., endplate sclerosis and facet joint osteoarthritis). Quality of included studies varied with the majority of studies demonstrating good quality.

Conclusion: A significant positive association was found with DSN and LBP that did not differ between community and occupational-based studies. The fact that no differences exist between these two groups may be related to the influence that genetic factors have on disc degeneration. A significant strong association was found between spondylolisthesis and LBP among the occupational group but was weakly associated in the community-based group, supporting spondylolisthesis as a potential unique pain generator in the lumbar spine.


Disclosure:

J. Raastad,
None;

M. Reiman,
None;

R. Coeytaux,
None;

L. Ledbetter,
None;

A. P. Goode,
None.

  • Tweet
  • Email
  • Print

« Back to 2014 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/the-association-between-low-back-pain-and-radiographic-features-a-systematic-review-with-meta-analysis/

Advanced Search

Your Favorites

You can save and print a list of your favorite abstracts during your browser session by clicking the “Favorite” button at the bottom of any abstract. View your favorites »

All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

Accepted abstracts are made available to the public online in advance of the meeting and are published in a special online supplement of our scientific journal, Arthritis & Rheumatology. Information contained in those abstracts may not be released until the abstracts appear online. In an exception to the media embargo, academic institutions, private organizations, and companies with products whose value may be influenced by information contained in an abstract may issue a press release to coincide with the availability of an ACR abstract on the ACR website. However, the ACR continues to require that information that goes beyond that contained in the abstract (e.g., discussion of the abstract done as part of editorial news coverage) is under media embargo until 10:00 AM ET on November 14, 2024. Journalists with access to embargoed information cannot release articles or editorial news coverage before this time. Editorial news coverage is considered original articles/videos developed by employed journalists to report facts, commentary, and subject matter expert quotes in a narrative form using a variety of sources (e.g., research, announcements, press releases, events, etc.).

Violation of this policy may result in the abstract being withdrawn from the meeting and other measures deemed appropriate. Authors are responsible for notifying colleagues, institutions, communications firms, and all other stakeholders related to the development or promotion of the abstract about this policy. If you have questions about the ACR abstract embargo policy, please contact ACR abstracts staff at [email protected].

Wiley

  • Online Journal
  • Privacy Policy
  • Permissions Policies
  • Cookie Preferences

© Copyright 2025 American College of Rheumatology