Session Information
Session Type: Abstract Submissions (ACR)
Background/Purpose:
The prevalence of axial spondyloarthritis (SpA) has not yet been investigated in a population based survey by using new ASAS classification criteria. The aim of this study was to determine the prevalence of axial SpA among university employees in Izmir, Turkey.
Methods:
The study was conducted in the Health Sciences Campus with a population of 2894 medical and non-medical staff at Dokuz Eylul University in Izmir. A sample size of 395 subjects was calculated by assuming that the inflammatory back pain (IBP) prevalence of 5% in the general population (1) using OpenEpi (version 2.3 Atlanta, GA, USA), based on a confidence interval of ±2%. Six trained medical students using a standard questionnaire performed a face-to-face interview with participants. The subjects who were classified as having IBP based on ASAS Experts’ criteria and other IBP criteria sets were invited to the Rheumatology out-patient clinic to participate in the study. They were evaluated for axial SpA by two rheumatologists using ASAS classification criteria. The patients with IBP were also evaluated to determine whether they met the modified New York (mNY) criteria for ankylosing spondylitis (AS) and both the ESSG and the Amor criteria for SpA.
Results:
A total of 381 subjects (131 male, 250 female; mean age: 38.0 ± 9.4) were contacted with an acceptance rate of 96.5%. Twenty five subjects (6.5 %; CI 95% 4.0-9.0) with back pain lasting ≥ 3 months were classified as having IBP according to ASAS Experts’ criteria. The prevalence of IBP according to Berlin and Calin criteria was found to be 7.0% (CI 95% 4.0-10.0) and 21.5% (CI 95% 17.0-25.0), respectively (Table).
Three subjects with IBP (0.78%) were classified as having axial SpA according to ASAS classification criteria. Two of these patients (0.52%) had radiographic sacroiliitis and they met the mNY criteria for AS . There were 8 patients (2.0%) who fulfilled both the Amor and ESSG criteria for whole group of SpA (Table). One of them had psoriasis.
Conclusion:
This is the first population-based survey of axial SpA using ASAS classification criteria. The prevalence estimates of IBP and SpA/axial SpA reported in this study are within the upper range of other studies in European countries and US.
Table. Prevalence of IBP and SpA according to various classification criteria in the university employees
|
|
Total % (CI 95%) |
Female % (CI 95%) |
Male % (CI 95%) |
|
IBP Criteria |
|
|
|
|
ASAS Experts’ |
6.5 (4.0-9.0) |
8.0 (5.0-12.0) |
3.0 (1.0-8.0) |
|
Berlin |
7.0 (4.0-10.0) |
8.0 (5.0-12.0) |
3.0 (1.0-8.0) |
|
Calin |
21.5 (17.0-25.0) |
24.2 (19.0-29.0) |
16.0 (11.0-24.0) |
|
ASAS Criteria for Axial SpA |
0.78 (0.16-2.30) |
0.80 (0.097-2.89) |
0.70 (0.02-4.25) |
|
MNY Criteria for AS |
0.52 (0.06-1.80) |
0.40 (0.01-2.20) |
0.70 (0.02-4.25) |
|
Amor Criteria for SpA |
2.00 (0.90-4.00) |
2.40 (0.88-5.22) |
1.40 (0.18-5.50) |
|
ESSG Criteria for SpA |
2.00 (0.90-4.00) |
2.40 (0.88-5.22) |
1.40 (0.18-5.50) |
IBP: inflammatory back pain; SpA: spondyloarthritis; MNY: modified New York; ESSG: European Spondyloarthropathy Study Group
Reference 1. Weismann MH et al. The prevalence of inflammatory back pain: population-based estimates from the US National Health and Nutrition Examination Survey, 2009-10. Ann Rheum Dis 2013 Mar;72(3):369-73
Disclosure:
F. Onen,
None;
D. Solmaz,
None;
P. Cetin,
None;
A. Balci,
None;
S. Akar,
None;
N. Akkoc,
None.
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