ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 1882

Predictors of a Favorable Outcome in Patients with Fibromyalgia: Results From the 1-Year Follow-up

Dong-Jin Park1, Shin-Seok Lee2, Seong-Ho Kim3, Seong-Su Nah4, Ji Hyun Lee5, Seong-Kyu Kim6, Yeon-Ah Lee7, Seung-Jae Hong7, Hyun-Sook Kim8, Hye-Soon Lee9, Hyoun Ah Kim10, Chung-Il Joung11 and Sang-Hyon Kim12, 1Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, 2Dept of Int Med/Rheumatology, Chonnam National University Medical School, Gwangju, South Korea, 3Department of Internal Medicine,, Inje University Haeundae Paik Hospital, Busan, South Korea, 4Rheumatology, Soonchunhyang University, South Korea, 5Division of Rheumatology, Department of Internal Medicine, Maryknoll Medical Center, Busan, South Korea, 6Catholic University of Daegu School of Medicine, Daegu, South Korea, 7Division of Rheumatology, Department of Internal Medicine, Kyung Hee University, Seoul, South Korea, 8Internal Medicine, Chosun University Hospital, Gwangju, South Korea, 9Department of Rheumatology, Hanyang University Guri Hospital, Guri, South Korea, 10Ajou University Hospital, Suwon, South Korea, 11Department of Internal Medicine, Konyang university hospital, Daejeon, South Korea, 12Division of Rheumatology, Department of Internal Medicine, Keimyung University School of Medicine, Daegu, South Korea

Meeting: 2012 ACR/ARHP Annual Meeting

Keywords:

Session Information

Title: Fibromyalgia and Soft Tissue Disorders

Session Type: Abstract Submissions (ACR)

Background/Purpose: To determine the outcomes in Korean patients with fibromyalgia (FM) and identify the prognostic factors associated with improvement at 1-year follow-up.

Methods: Forty-eight patients with FM were enrolled and examined every 3 months for 1-year. We interviewed these patients using a structured questionnaire that included sociodemograhpic data, current or past FM symptoms, and current use of relevant medications at the time of enrollment. Tender point counts and scores were assessed by thumb palpation. Patients were asked to complete a Korean version of the Fibromyalgia Impact Questionnaire (FIQ), the Brief Fatigue Inventory, the SF-36, the Beck Depression Inventory, the State-Trait Anxiety Inventory, the Self-Efficacy Scale, and the Social Support Scale. During follow-up, tender points, FIQ, and current use of relevant medications were recorded during 1 year follow-up period.

Results: Of the 48 patients, 32 (66.7%) had improved FIQ scores 1 year after enrollment. The improved patients had higher baseline FIQ scores (68.4±13.9 vs 48.4±20.8, p=0.001) and higher Trait Anxiety Inventory scores (55.8±10.9 vs 11.5±11.5, p=0.022). The patients treated with pregabalin which was added during the follow-up period were more likely to be improved after 1-year (71.9 % vs 37.5 %, p=0.031). In multivariate logistic regression analyses, the additional use of pregabalin and higher Trait Anxiety Inventory scores at baseline were the predictor of improvement (p=0.026 and p=0.043) and this statistical significance persisted after adjustment for age, gender, and disease duration (p=0.016 and p=0.037).

Conclusion: Two-thirds of the Korean FM patients experienced some clinical improvement by 1-year after enrollment. The use of pregabalin and anxiety were shown to be important predictors of improved FM. Interventions, particularly medications, may be associated with good outcome in a significant number of these patients.

Disclosure:

D. J. Park,
None;

S. S. Lee,
None;

S. H. Kim,
None;

S. S. Nah,
None;

J. H. Lee,
None;

S. K. Kim,
None;

Y. A. Lee,
None;

S. J. Hong,
None;

H. S. Kim,
None;

H. S. Lee,
None;

H. A. Kim,
None;

C. I. Joung,
None;

S. H. Kim,
None.

« Back to 2012 ACR/ARHP Annual Meeting

ACR Meeting Abstracts - https://acrabstracts.org/abstract/predictors-of-a-favorable-outcome-in-patients-with-fibromyalgia-results-from-the-1-year-follow-up/