ACR Meeting Abstracts

ACR Meeting Abstracts

Abstract Number: 2195

Predictive Factors of a Positive PET/CT Scan for Vascular Involvement in Patients with Polymyalgia Rheumatica

Diana Prieto Peña1, Monica Calderón Goercke1, Javier Loricera2, Isabel Martínez-Rodríguez3, Ignacio Banzo3, Belén Atienza-Mateo4, José Luis Martín-Varillas4, Vanesa Calvo-Río1, Carmen Gonzalez Vela5, Alfonso Corrales4, Santos Castañeda6, Ricardo Blanco4, José Luis Hernández2 and Miguel Angel González-Gay7, 1Rheumatology, Rheumatology. Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 3Nuclear Medicine, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 4Rheumatology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 5Pathology, Hospital Universitario Marqués de Valdecilla. IDIVAL. Santander. Universidad de Cantabria. Spain, Santander, Spain, 6Rheumatology, Rheumatology Department, Hospital Universitario la Princesa, IIS-Princesa, Madrid, Spain, 7Hospital Universitario Marqués de Valdecilla, University of Cantabria Santander, Santander, Spain

Meeting: 2018 ACR/ARHP Annual Meeting

Keywords:

Session Information

Date: Tuesday, October 23, 2018

Title: Imaging of Rheumatic Diseases Poster III: Other Modalities

Session Type: ACR Poster Session C

Session Time: 9:00AM-11:00AM

Background/Purpose:

Polymyalgia rheumatica (PMR) is often the presenting manifestation of giant cell arteritis (GCA). Fluorine-18-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT) scan often discloses the presence of LVV in PMR patients. We aimed to identify predictive factors of a positive PET/CT scan for LVV in patients classified as having isolated PMR.

Methods:

A set of consecutive patients with PMR from a single hospital were assessed. All of them underwent PET/CT scan between January 2010 and February 2018 based on clinical considerations. Patients with PMR associated to other diseases, including those with cranial features of GCA, were excluded. The remaining patients were categorized in classic PMR (if fulfilled the 2012 EULAR/ACR classification criteria at disease diagnosis; n=84) or atypical PMR (who did not fulfill these criteria; n=16). Only information on patients with classic PMR was assessed.

Results:

The mean age of the 84 patients (50 women) with classic PMR was 71.4±9.2 years. A PET/CT scan was positive in 51(60.7%). Persistence of classic PMR symptoms was the most common reason to perform a PET/CT scan. Nevertheless, patients with positive PET/CT scan often had unusual symptoms. The best set of predictors of a positive PET/CT scan were bilateral diffuse lower limb pain (OR=8.8, 95% CI 1.7-46.3; p=0.01), pelvic girdle pain (OR=4.9, 95% CI 1.50-16.53; p=0.01) and inflammatory low back pain (OR=4.7, 95% CI 1.03-21.5; p=0.04).

Conclusion:

Inflammatory low back pain, pelvic girdle and diffuse lower limb pain are predictors of positive PET/CT scan for LVV in PMR.

Descripción: C:\Users\DIANA\Desktop\Figure 3 PMR&LVV.jpg

Disclosure: D. Prieto Peña, None; M. Calderón Goercke, None; J. Loricera, None; I. Martínez-Rodríguez, None; I. Banzo, None; B. Atienza-Mateo, None; J. L. Martín-Varillas, None; V. Calvo-Río, None; C. Gonzalez Vela, None; A. Corrales, None; S. Castañeda, None; R. Blanco, None; J. L. Hernández, None; M. A. González-Gay, None.

To cite this abstract in AMA style:

Prieto Peña D, Calderón Goercke M, Loricera J, Martínez-Rodríguez I, Banzo I, Atienza-Mateo B, Martín-Varillas JL, Calvo-Río V, Gonzalez Vela C, Corrales A, Castañeda S, Blanco R, Hernández JL, González-Gay MA. Predictive Factors of a Positive PET/CT Scan for Vascular Involvement in Patients with Polymyalgia Rheumatica [abstract]. Arthritis Rheumatol. 2018; 70 (suppl 9). https://acrabstracts.org/abstract/predictive-factors-of-a-positive-pet-ct-scan-for-vascular-involvement-in-patients-with-polymyalgia-rheumatica/. Accessed .

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