Session Type: ACR Poster Session A
Session Time: 9:00AM-11:00AM
Methods employed to assess medication adherence in the SLE population include patient self-report questionnaires, pharmacy refill record review, physician impressions of patient adherence, and therapeutic drug monitoring; however, few studies undertake a multifactorial methodology.
Results: Adherence was assessed on 30 patients; 20 patients were considered adherent by resultant detectable MPA levels. In a univariate regression model, pharmacy refill percentage had the strongest correlation with detectable MPA levels (Pearson’s Correlation r value=0.464, p-value=0.0128), while both the MASRI and the physician rating showed only modest correlations with MPA level (Pearson’s Correlation r values of 0.227 and 0.202, respectively). There was a statistically significant (p=0.0041) difference in the refill percentages, with majority of the adherent cohort (80%) having refill percentages of 80% or greater. Patients in the adherent group were slightly older, with a mean age of 40.8 (p=0.0473) and were more likely to be married (p=0.0187).
To cite this abstract in AMA style:Ghaderi-Yeganeh M, Biehl A, Manna ZG, Fike A, Hasni S. Patient Adherence with Mycophenolate Mofetil Therapy in a Systemic Lupus Erythematosus Cohort: A Multi-Factorial Assessment [abstract]. Arthritis Rheumatol. 2016; 68 (suppl 10). https://acrabstracts.org/abstract/patient-adherence-with-mycophenolate-mofetil-therapy-in-a-systemic-lupus-erythematosus-cohort-a-multi-factorial-assessment/. Accessed December 4, 2021.
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ACR Meeting Abstracts - https://acrabstracts.org/abstract/patient-adherence-with-mycophenolate-mofetil-therapy-in-a-systemic-lupus-erythematosus-cohort-a-multi-factorial-assessment/