Abstracts Archive - Page 989 of 2607 - ACR Meeting Abstracts

Abstract Number: 733 • 2019 ACR/ARP Annual Meeting
Vonoprazan, a Novel Potassium-competitive Acid Blocker, for Treatment of Proton Pump Inhibitor-resistant Reflux Esophagitis in Patients with Systemic Sclerosis
Yuichiro Shirai¹, Noriyuki Kawami ², Katsuhiko Iwakiri ² and Masataka Kuwana ¹, ¹Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, Bunkyo-ku, Tokyo, Japan, ²Department of Gastroenterology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, Bunkyo-ku, Tokyo, Japan
Background/Purpose: Esophageal involvement is one of the most frequent organ manifestations in patients with systemic sclerosis (SSc). Gastroesophageal reflux disease (GERD) is associated with reflux…
Abstract Number: 734 • 2019 ACR/ARP Annual Meeting
Risk Assessment in Connective Tissue Disease Associated Pulmonary Arterial Hypertension
Yuichiro Shirai¹, Hidekata Yasuoka ², Yuichi Tamura ³ and Masataka Kuwana ¹, ¹Department of Allergy and Rheumatology, Nippon Medical School Graduate School of Medicine, Tokyo, Japan, Bunkyo-ku, Tokyo, Japan, ²Division of Rheumatology, Department of Internal Medicine, Fujita Health University School of Medicine, Aichi, Japan, Toyoake, Aichi, Japan, ³Pulmonary Hypertension Center, International University of Health and Welfare Mita Hospital, Tokyo, Japan, Tokyo, Japan
Background/Purpose: Pulmonary arterial hypertension (PAH) still holds a poor prognosis in patients with connective tissue diseases (CTD), especially those with systemic sclerosis (SSc). A variety…
Abstract Number: 735 • 2019 ACR/ARP Annual Meeting
The Relationship Between Gastrointestinal Symptoms and Severity and Whole Gut Transit in Patients with Systemic Sclerosis
Zsuzsanna McMahan* ¹, Ana Tucker*², Jamie Perin ³, Jay Pasricha ⁴, Harvey Ziessman ⁵, Antony Rosen ¹ and Frederick Wigley ¹, ¹Johns Hopkins University, Division of Rheumatology, Baltimore, ²Johns Hopkins Bayview Medical Center, Baltimore, MD, ³Johns Hopkins University School of Public Health, Department of International Health, Baltimore, ⁴Johns Hopkins University, Division of Gastroenterology, Baltimore, ⁵Johns Hopkins University, Division of Radiology, Baltimore
Background/Purpose: The gastrointestinal (GI) tract is the most commonly affected internal organ system in systemic sclerosis (SSc), resulting in significant morbidity and mortality. Several studies…
Abstract Number: 736 • 2019 ACR/ARP Annual Meeting
Reduced Circulating Levels of Inorganic Pyrophosphate Are Associated with Ectopic Calcification in Scleroderma Spectrum Disorders
Vivien Hsu¹, Naomi Schlesinger ², Qiaoli Li ³ and John Varga ⁴, ¹Rutgers- RWJ Medical School, SOUTH PLAINFIELD, NJ, ²Rutgers Health- RWJ Medical School, New Brunswick, NJ, ³Thomas Jefferson University, Philadelphia, PA, ⁴Northwestern University, Chicago,, IL
Background/Purpose: Calcinosis cutis due to ectopic mineralization is a common and disabling complication of systemic sclerosis (SSc) that has poorly understood pathogenesis and no effective…
Abstract Number: 737 • 2019 ACR/ARP Annual Meeting
The MUC5B Promoter Variant Does Not Predict Outcomes in Systemic Sclerosis-related Interstitial Lung Disease
Elizabeth Volkmann¹, Donald Tashkin ², Michael Roth ³, Ning Li ², Grace Kim ², Jonathan Goldin ², Maureen Mayes ⁴, Julio Charles ⁵, Philip Clements ², Daniel Furst ⁶, Dinesh Khanna ⁷, Robert Elashoff ² and Shervin Assassi ⁴, ¹University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, ²University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, ³University of California, Los Angeles, David Geffen School of Medicine, Los Angeles, CA, ⁴Division of Rheumatology and Clinical Immunogenetics, University of Texas McGovern Medical School, Houston, Texas, USA, Houston, TX, ⁵University of Texas, Houston, Houston, ⁶University of California, Los Angeles, CA, ⁷Department of Medicine, University of Michigan, Ann Arbor, Michigan, USA, Ann Arbor
Background/Purpose: Interstitial lung disease (ILD) affects the majority of patients with systemic sclerosis (SSc). The disease course of ILD varies among SSc patients and no…
Abstract Number: 738 • 2019 ACR/ARP Annual Meeting
Systemic Sclerosis Myocarditis Has Unique Clinical, Histological and Prognostic Features: Comparative Analysis Between Patients with Endomyocardial Biopsy-proven Myocarditis
Giacomo De Luca¹, Silvia Bosello ², Corrado Campochiaro ¹, Silvia Sartorelli ³, Giovanni Peretto ⁴, Simone Sala ⁵, Giovanni Canestrari ², Gaetano Thiene ⁶, Cristina Basso ⁶, Paolo Della Bella ⁴, Elisa Gremese ⁷ and Lorenzo Dagna ¹, ¹Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy, ²Rheumathology Division, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy, ³Vita-Salute San Raffaele University, IRCCS San Raffaele Hospital, Milan, Italy, ⁴Department of Cardiac Electrophysiology and Arrhythmology, IRCCS San Raffaele Hospital, Milan, Italy, ⁵Department of Cardiac Electrophysiology and Arrhythmology, IRCCS San Raffaele Hospital, Mialn, Italy, ⁶Cardiovascular Pathology Unit, Department of Cardiac, Thoracic and Vascular Sciences, University and Hospital of Padua, Padua, Italy, ⁷Division of Rheumatology - Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy
Background/Purpose: Myocarditis is a life-threatening inflammatory disease increasingly reported in Systemic Sclerosis(SSc); the histological, clinical and prognostic features of SSc-myocardits have not been elucidated yet.…
Abstract Number: 739 • 2019 ACR/ARP Annual Meeting
Does Digital Thermal Monitoring Correlate to Specific Nailfold Videocapillaroscopy Abnormalities?
Mislav Radic¹, Rebecca Overbury ² and Tracy Frech ³, ¹University Hospital Split, Split, Croatia, ²University of Utah, Departments of Pediatrics and Internal Medicine, Division of Rheumatology, Salt Lake City, UT, ³Division of Rheumatology, University of Utah and Salt Lake VAMC, Salt Lake City, UT
Background/Purpose: The fingers have specialized structural and functional features for thermoregulation, and are the most common areas of Raynaud’s phenomenon (RP) in systemic sclerosis (SSc).…
Abstract Number: 740 • 2019 ACR/ARP Annual Meeting
Rituximab Rescue Therapy in Patients with Systemic Sclerosis or Other Connective Tissue Diseases and Refractory Interstitial Lung Disease
Magdalena Benad ¹, Dirk Koschel ¹, Kristine Herrmann ¹, Kristin Wiefel ¹, Alexander Kleymann ¹ and Martin Aringer², ¹University Medical Center and Faculty of Medicine TU Dresden, Dresden, Germany, ²Division of Rheumatology, Department of Medicine III, University Medical Center & Faculty of Medicine Carl Gustav Carus, TU Dresden, Dresden, Germany, Dresden, Germany
Background/Purpose: Interstitial lung disease (ILD) is a common and life-threatening organ manifestation of patients with various connective tissue diseases (CTDs), and with systemic sclerosis and…
Abstract Number: 741 • 2019 ACR/ARP Annual Meeting
Vascular Damage Is Less Present in an Early Inception Cohort in Takayasu’s Arteritis
Fatma Alibaz-Oner¹, ¹Marmara University Faculty of Medicine,Department of Rheumatology,Istanbul,Turkey, Istanbul, Turkey
Background/Purpose: There is only retrospective and very limited data for the long term prognosis of Takayasu's Arteritis (TAK), a rare large-vessel vasculitis. In this study,…
Abstract Number: 742 • 2019 ACR/ARP Annual Meeting
Polymyalgia Rheumatica: New Therapeutic Strategy Based on Low Dose Metrotexate Plus Local Infiltration with Corticosteroids
Miriam Retuerto¹, Pilar Fernández-Dapica ², Patricia Lavilla ³, Fernando Lozano ³, M. Eva Vallejo ⁴ and José Luis Pablos ⁵, ¹Rheumatology Department. Instituto de Investigación Hospital 12 de Octubre (i+12), Madrid, Spain, ²Hospital universitario 12 de octubre, Instituto de investigacion hospital 12 de octubre (i+12), Madrid, Spain, ³Rheumatology Department. Hospital universitario 12 de octubre, Instituto de investigacion hospital 12 de octubre (i+12), Madrid, Spain, ⁴Facultad de CC. EE y Empresariales, Universidad de Leon, Leon, Spain, ⁵Rheumatology Department. Hospital universitario 12 de octubre, Instituto de investigacion hospital 12 de octubre (i+12), Universidad Complutense de Madrid, Madrid, Spain
Background/Purpose: Polymyalgia rheumatic (PMR) is a common rheumatic inflammatory disease in the elderly. Glucocorticoids (GC) are the therapeutic mainstay in PMR but induce significant toxicity…
Abstract Number: 743 • 2019 ACR/ARP Annual Meeting
Association Between Acute-phase Reactants, interleukin-6(IL6), Tumor Necrosis Factor-a(TNFa) and Disease Activity in Takayasu’s Arteritis During Follow-up with Repeated Evaluation of Vascular Imaging Manifestations
JIng LI¹, Yunjiao Yang ¹, Yanhong WANG ², Jiuliang Zhao ¹, Mengtao Li ³, Xinping Tian ¹ and Xiaofeng Zeng ¹, ¹Peking Union Medical College Hospital, Beijing, China (People's Republic), ²Institute of Basic Medical Sciences, Chinese Academy of Medical Sciences, School of Basic Medicine, Beijing, China (People's Republic), ³Dept. of Rheumatology, Peking Union Medical College Hospital (West Campus), Beijing, China, Beijing, China (People's Republic)
Background/Purpose: To investigate the laboratory indicators of disease activity during follow-up of Takayasu’s arteritis(TAK).Methods: Electronic data of 588 patients with TAK enrolled in the Chinese…
Abstract Number: 744 • 2019 ACR/ARP Annual Meeting
Are Hematologic Indexes Helpful in the Diagnosis and Prognosis of Polymyalgia Rheumatica?
María de la Torre¹ and Cecilia Pisoni ¹, ¹Centro de Educación Médica e Investigaciones Clínicas Norberto Quirno (CEMIC), Ciudad Autónoma de Buenos Aires, Buenos Aires, Argentina
Background/Purpose: Recently, the use of hematologic indexes as markers of systemic inflammation has been reported in oncological, cardiovascular and rheumatic diseases. Only 2 studies evaluated…
Abstract Number: 745 • 2019 ACR/ARP Annual Meeting
Cardiac Involvements Are Related to Poor Prognosis in Patients with Takayasu’s Arteritis in China
Yujiao Wang¹, Lili Ma ¹, Yan Yan ², Ying Sun ³, Yongshi Wang ⁴, Xiaomin Dai ¹, Zongfei Ji ⁵, Lingying Ma ¹, Huiyong Chen ³ and Lindi Jiang ¹, ¹Zhongshan Hospital, Fudan University, Shanghai, China (People's Republic), ²Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai, China (People's Republic), ³Department of Rheumatology, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai, ⁴Department of Echocardiography, Zhongshan Hospital, Fudan University, Shanghai, P. R. China, Shanghai, ⁵Department of Rheumatology, Zhongshan hospital, Fudan University, Shanghai, China (People's Republic)
Background/Purpose: Heart involvements are closely associated with prognosis in patients with Takayasu’s arteritis (TA). This study was aimed to assess the long-term adverse outcomes of…
Abstract Number: 746 • 2019 ACR/ARP Annual Meeting
Childhood-Onset Takayasu’s Arteritis (TAK) Is Clinically More Active, However Has Similar Cumulative Damage Compared to Adult-Onset TAK
Murat Karabacak¹, Sema Kaymaz-Tahra ², Sezgin Sahin ³, Mehmet Yıldız ⁴, Amra Adrovic ⁵, Kenan Barut ⁶, Haner Direskeneli ⁷, Ozgur Kasapcopur ⁸ and Fatma Alibaz-Oner ¹, ¹Marmara University Faculty of Medicine,Department of Rheumatology,Istanbul,Turkey, Istanbul, Turkey, ²Marmara University School of Medicine, Division of Rheumatology, Istanbul, Istanbul, Turkey, ³Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Istanbul, Turkey, ⁴Department of Pediatric Rheumatology, Istanbul University Cerrahpasa, Istanbul, Istanbul, Turkey, ⁵Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey, ⁶Department of Pediatric Rheumatology, Cerrahpasa Medical School, Istanbul University-Cerrahpasa, Istanbul, Turkey, İstanbul, Istanbul, Turkey, ⁷Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey, ⁸Department of Pediatric Rheumatology, Istanbul University-Cerrahpasa, Istanbul, Turkey, Istanbul, Turkey
Background/Purpose: Childhood-onset Takayasu’s Arteritis (TAK) may differ in presentation, clinical manifestations and treatment, as previously shown1. We aimed to compare the clinical manifestations, vascular involvement…
Abstract Number: 747 • 2019 ACR/ARP Annual Meeting
Detrimental Factors Affecting the First-year Clinical Response in Korean Patients with Polymyalgia Rheumatica
Yoon-Jeong Oh ¹, Seung Min Jung ², Byoong Yong Choi ³ and Kichul Shin⁴, ¹Kanwon National University Hospital, Chuncheon, Republic of Korea, ²Yonsei university college of medicine, severance hospital, Seodaemun-gu, Republic of Korea, ³Seoul Medical Center, Seoul, Republic of Korea, ⁴Department of Internal Medicine, Seoul Metropolitan Government-Seoul National University Boramae Medical Center, Seoul, Korea., seoul, Republic of Korea
Background/Purpose: Polymyalgia rheumatica (PMR) is a chronic inflammatory disease in which patients respond well to glucocorticoids (GCs). However, a number of patients experience a flare…

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