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  • Abstract Number: 2485 • 2019 ACR/ARP Annual Meeting

    Red Cell Distribution Width Positively Correlates with Atherosclerotic Cardiovascular Disease Risk Score in Psoriatic Arthritis and Decreases with BDMARD Therapy

    Angela Gupta1, Sofi Damjanovska 2, David Zidar 3, Donald Anthony 4 and Maya Mattar 3, 1Case Western Reserve University, Cleveland, 2Case Western Reserve University, Cleveland Heights, OH, 3Louis Stokes Cleveland VA Medical Center, Cleveland, OH, 4Case Western Reserve University, Cleveland, OH

    Background/Purpose: Red blood cell distribution width (RDW) is a parameter that measures variation in red blood cell size and volume. It is elevated when there…
  • Abstract Number: 2486 • 2019 ACR/ARP Annual Meeting

    Evaluation of Clinical and Functional Parameters by Joint Involvement and Remission in Psoriatic Arthritis

    Halise Hande Gezer1, Mehmet Tuncay Duruoz 2, Kemal Nas 3, Erkan Kilic 4, Betul Sargin 5, Sevtap Acer Kasman 2, Hakan Alkan 6, Nilay Sahin 7, Gizem Cengiz 8, Nihan Cuzdan 9, Ilknur Albayrak Gezer 10, Dilek Keskin 11, Cevriye Mulkoglu 12, Hatice Resorlu 13, Ismihan Sunar 14, Ajda Bal 15, Okan Kucukakkas 16, Ozan Volkan Yurdakul 16, Meltem Alkan Melikoglu 17, Yildiray Aydin 3, Fikriye Figen Ayhan 18, Hatice Bodur 19, Mustafa Calis 8, Erhan Capkin 20, Gul Devrimsel 21, Kevser Gök 22, Sami Hizmetli 23, Ayhan Kamanli 3, Yasar Keskin 16, Hilal Kocabas 24, Oznur Kutluk 25, Nesrin Sen 26, Omer Faruk Sendur 27, Ibrahim Tekeoglu 3, Sena Tolu 28, Murat Toprak 29 and Tiraje Tuncer 25, 1Marmara University School of Medicine, PMR Department, Rheumatology Division, İstanbul, Istanbul, Turkey, 2Marmara University School of Medicine, PMR Department, Rheumatology Division, İstanbul, Turkey, 3Sakarya University School of Medicine, PMR Department, Rheumatology and Immunology Division, Sakarya, Turkey, 4Afyonkarahisar State Hospital, Afyonkarahisar, Turkey, 5Adnan Menderes University School of Medicine, PMR Department, Rheumatology Division, Aydın, Turkey, 6Pamukkale University School of Medicine, PMR Department, Rheumatology Division, Denizli, Turkey, 7Balıkesir University School of Medicine, PMR Department, Balıkesir, Turkey, 8Erciyes University School of Medicine, PMR Department, Rheumatology Division, Kayseri, Turkey, 9Şanlıurfa Training and Research Hospital, Rheumatology Clinic, Şanlıurfa, Turkey, 10Selçuk University School of Medicine, PMR Department, Konya, Turkey, 11Kırıkkale University School of Medicine, PMR Department, Kırıkkale, Turkey, 12Ankara Training and Research Hospital, PMR Clinic, Ankara, Turkey, 13Çanakkale Onsekiz Mart University School of Medicine, PMR Department, Çanakkale, Turkey, 14Ankara Unversity School of Medicine, Physical Medicine and Rehabilitation, Rheumatology Department, Ankara, Turkey, 15Dışkapı Yıldırım Beyazıt Training and Research Hospital, PMR Clinic, Ankara, Turkey, 16Bezmialem Vakıf University School of Medicine, PMR Department, İstanbul, Turkey, 17Atatürk University School of Medicine, PMR Department, Rheumatology Division, Erzurum, Turkey, 18Uşak University School of Health Sciences, PMR Department, Uşak, Turkey, 19Yıldırım Beyazıt University School of Medicine, PMR Department, Ankara, Turkey, 20Karadeniz Teknik University School of Medicine, PMR Department, Trabzon, Turkey, 21Recep Tayyip Erdoğan University School of Medicine, PMR Department, Riza, Turkey, 22Numune Training and Research Hospital, Rheumatology Clinic, Ankara, Turkey, 23Cumhuriyet University School of Medicine, PMR Department, Rheumatology Division, Sivas, Turkey, 24Necmettin Erbakan University Meram School of Medicine, PMR Department, Rheumatology Division, Konya, Turkey, 25Akdeniz University School of Medicine, PMR Department, Rheumatology Division, Antalya, Turkey, 26Kartal Dr. Lütfi Kırdar Training and Research Hospital, Rheumatology Clinic, İstanbul, Turkey, 27Adnan Menderes University School of Medicine, PMR Department, Aydın, Turkey, 28Medipol University School of Medicine, PMR Department, İstanbul, Turkey, 29Yüzüncü Yıl University School of Medicine, PMR Department, Van, Turkey

    Background/Purpose: Disease activity of psoriatic arthritis (PsA) is affected by many parameters including joint, spinal and skin involvement, enthesitis, dactylitis and pain. According to disease…
  • Abstract Number: 2487 • 2019 ACR/ARP Annual Meeting

    Identification of Circulating MicroRNA Signatures in Patients with Psoriasis and Psoriatic Arthritis to Develop Novel Strategies for Early Diagnosis of a Bone and Joint Involvement

    Judith Haschka1, David Simon 2, Sara Bayat 3, Arnd Kleyer 3, Eleni Kampylafka 3, Axel Hueber 4, Christian Muschitz 5, Susanna Skalicky 6, Matthias Hackl 6, Heinrich Resch 1, Georg Schett 7, Roland Kocijan 8 and Jürgen Rech 9, 1Karl Landsteiner Institute for Gastroenterology and Rheumatology, St. Vincent Hospital Vienna, II Medical Department, Vienna, Austria, 2Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Bayern, Germany, 3Department of Internal Medicine 3 – Rheumatology and Immunology, Friedrich-Alexander-University Erlangen-Nürnberg, University Hospital Erlangen, Erlangen, Germany, Erlangen, Germany, 4Sozialstiftung Bamberg, Klinikum Bamberg, Section Rheumatology, Bamberg, Germany, Bamberg, Germany, 5St. Vincent Hospital Vienna, II Medical Department, VINFORCE Study Group, Vienna, Austria, 6TAmiRNA GmbH, Vienna, Austria, Vienna, Austria, 7Department of Internal Medicine 3, Friedrich Alexander University Erlangen-Nuremberg, Erlangen, Germany, 8Ludwig Boltzmann Institute for Experimental and Clinical Traumatology, Vienna, Austria, 9Department of Internal Medicine 3, Friedrich-Alexander-University Erlangen-Nuremberg (FAU) and Universitätsklinikum Erlangen, Erlangen, Germany

    Background/Purpose: MicroRNAs (miRNAs) are small non-coding RNAs which are regulating physiologic and pathological processes. In numerous diseases specific miRNA signatures have been identified and can…
  • Abstract Number: 2488 • 2019 ACR/ARP Annual Meeting

    MDA Versus DAPSA: Applicability in a Real World

    rafaela Gonçalves1, Lays Martins 2, henrique mariz 1, marina brito 3, georgia pereira 3, andrea dantas 3 and Angela Duarte 2, 1clinical hospital of federal university of pernambuco, recife, Pernambuco, Brazil, 2Universidade Federal de Pernambuco, Recife, Brazil, 3clinical hospital of federal university of pernambuco, recife, Brazil

    Background/Purpose: Background/Purpose: Psoriatic arthritis (PsA) is a progressive, chronic, and potentially irreversible inflammatory disorder. Systematic clinical follow-up of PsA patients is necessary to maintain and…
  • Abstract Number: 2489 • 2019 ACR/ARP Annual Meeting

    Differences in Clinical Characteristics, Quality of Life, Disability, and Work Productivity in Psoriatic Arthritis Patients by Gender: Findings from a Cross-sectional Survey in the US and Europe

    Laure Gossec1, Jessica Walsh 2, Kaleb Michaud 3, Steve Peterson 4, Elizabeth Holdsworth 5, Chetan Karyekar 4, Nicola Booth 6, Jessalyn Kemp 7, Soumya Chakravarty 8, Shelly Kafka 9 and Alexis Ogdie 10, 1Sorbonne Université and Hôpital Pitié-Salpêtrière, Paris, France, 2Division of Rheumatology, University of Utah, Salt Lake City, UT, 3University of Nebraska Medical Center, Omaha, NE, 4Janssen Global Services, LLC, Horsham, PA, 5Adelphi Real World, Manchester, England, United Kingdom, 6Adelphi Real World, Bollington, United Kingdom, 7Adelphi Real World, Manchester, United Kingdom, 8Janssen Scientific Affairs, LLC; Drexel University College of Medicine, Horsham; Philadelphia, PA, 9Janssen Scientific Affairs, LLC, Horsham, PA, 10Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA

    Background/Purpose: Psoriatic arthritis (PsA) prevalence is equal in men and women, though gender may play a role in driving mechanisms of PsA leading to differences…
  • Abstract Number: 2490 • 2019 ACR/ARP Annual Meeting

    The Cutaneous Microbiome of Psoriatic Disease Is Influenced by Disease Susceptibility HLA Alleles but Not Clinical Phenotype

    Meital Yerushalmi1, Osvaldo Espin-Garcia 2, Justine (Yang) Ye 3, Remy Pollock 4, Sara Rahmati 3, Lihi Eder 5, Mark Silverberg 6 and Vinod Chandran 7, 1University of Toronto, University Health Network, Toronto, ON, Canada, 2Division of Biostatistics, Dalla Lana School of Public Health, University of Toronto, Toronto, ON, Canada, 3University Health Network, University of Toronto, Toronto, ON, Canada, 4Krembil Research Institute, University Health Network, Toronto, Canada, 5Women’s College Hospital and the Department of Medicine, University of Toronto, Toronto, Canada, 6Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada, 7University Health Network, University of Toronto, Toronto, Canada

    Background/Purpose: Psoriasis is an inflammatory skin disease. Psoriatic arthritis (PsA) is an inflammatory arthritis that affects 30% of psoriasis patients. The heterogeneity of psoriatic disease…
  • Abstract Number: 2491 • 2019 ACR/ARP Annual Meeting

    Predictors of DAPSA28 Remission at 6 Months in Bio-Naive Patients with Psoriatic Arthritis Starting a TNF Inhibitor in Clinical Practice– Results from the EuroSpA Collaboration

    Lykke Midtbøll Ørnbjerg1, Stylianos Georgiadis 2, Lennart Jacobsson 3, Anne Gitte Loft 4, Florenzo Iannone 5, Burkhard Moeller 6, Joe Sexton 7, Herman Mann 8, Maria José Santos 9, Manuel Pombo-Suarez 10, Kari K. Eklund 11, Matija Tomsic 12, Bjorn Gudbjornsson 13, Şükran Erten 14, Catalin Codreanu 15, Irene van der Horst-Bruinsma 16, Johan Wallman 17, Marco Sebastiani 18, Michael J. Nissen 19, Eirik Kristianslund 20, Karel Pavelka 8, Elsa Vieira-Sousa 21, Carlos Sánchez-Piedra 22, Nina Trokovic 23, Ziga Rotar 24, Thorvardur J Love 25, servet Yolbas 26, Ruxandra IONESCU 27, Marleen van de Sande 16, Gareth Jones 28, Brigitte Michelsen 29, Mikkel Østergaard 30 and Merete Lund Hetland 1, 1DANBIO and Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre of Head and Orthopaedics, Rigshospitalet, Copenhagen, Denmark, 2DANBIO registry and Copenhagen Center for Arthritis Research, Centre for Rheumatology and Spine Diseases, Rigshospitalet, Copenhagen, Denmark, 3Dept of Rheumatology and Inflammation Research, Institute of Medicine, Sahlgrenska Academy, University of Gothenburg, Sweden,, Gothenburg, Sweden, 4Department of Rheumatology, Aarhus University Hospital., Aarhus, Denmark, 5Department of Emergency and Transplantation , Rheumatology Unit, University Hospital of Bari, Bari, Italy., Bari, Italy, 6University Hospital Bern, Bern, Switzerland, 7Diakonhjemmet Hospital, Dept. of Rheumatology, Oslo, Norway, 8Institute of Rheumatology, Department of Rheumatology, 1st Faculty of Medicine, Prague, Czech Republic, Prague 2, Czech Republic, 9Rheumatology department, Hospital Garcia de Orta, Almada, Portugal, 10Unit Research, Spanish Society of Rheumatology, Madrid, Spain, 11ROB-FIN registry, Department of Medicine, Helsinki University and University Hospital, Helsinki, Finland, 12Department of Rheumatology, University Medical Centre, Ljubjana, Slovenia, 13Centre for Rheumatology Research, Landspitali and Faculty of Medicine, University of Iceland, Reykjavik, Iceland, 14Yıldırım Beyazıt University, Ankara, Turkey, 15Center of Rheumatic Diseases, University of Medicine and Pharmacy, Bucharest, Romania., Bucharest, Romania, 16Amsterdam University Medical Center, Amsterdam, Netherlands, 17Department of Clinical Sciences Lund, Rheumatology Lund University, Lund, Sweden, 18Rheumatology Unit, Department of Surgery, Medicine, Dentistry and Morphological Sciences with Transplant Surgery, Oncology and Regenerative Medicine Relevance, Azienda Policlinico di Modena, University of Modena and Reggio Emilia, Modena, Italy, 19University Hospital Geneva, Geneva, Switzerland, 20Department of Rheumatology, Diakonhjemmet Hospital, Oslo, Norway., Oslo, Norway, 21Rheumatology and Metabolic Bone Diseases, Hospital de Santa Maria - Centro Hospitalar Lisboa Norte, EPE | Rheumatology Research Unit, Instituto de Medicina Molecular - Faculty of Medicine, University of Lisbon, Lisbon Academic Medical Centre, Lisbon, Portugal,, Lisbon, Portugal, 22Research Unit, Spanish Society of Rheumatology, Madrid, Spain, 23Helsinki University Central Hospital, Helsinki, Finland, 24UMC LJUBLJANA, DPT. OF RHEUMATOLOGY, LJUBLJANA, Slovenia, 25Faculty of Medicine, University of Iceland, Reykjavik, Iceland, 26TURKBIO registry and Celal Bayar University School of Medicin, Division of Rheumatology, Malatya, Turkey, 27SPITALUL CLINIC SFANTA MARIA, Bucharest, 28University of Aberdeen, Aberdeen, United Kingdom, 29EuroSpA Coordinating Center, Copenhagen Center for Arthritis Research (COPECARE), Center for Rheumatology and Spine Diseases, Centre for Head and Orthopaedics, Rigshospitalet, Glostrup, Glostrup, Denmark, 30Copenhagen Center for Arthritis Research, University of Copenhagen, Copenhagen, Denmark

    Background/Purpose: Tumor necrosis factor inhibitors (TNFi) have contributed to improved prognosis in patients with psoriatic arthritis (PsA). However, many patients treated with TNFi fail to…
  • Abstract Number: 2492 • 2019 ACR/ARP Annual Meeting

    Efficacy and Safety of Disease-Modifying Drugs in Psoriatic Arthritis (PsA): A Systematic Literature Review

    Andreas Kerschbaumer1, Josef Smolen 1, Maxime Dougados 2, Maarten de Wit 3, Jette Primdahl 4, Iain McInnes 5, Désirée van der Heijde 6, Louise Falzon 7, Xenofon Baraliakos 8 and Laure Gossec 9, 1Medical University of Vienna, Vienna, Austria, 2Cochin Hospital, Paris, France, 3Department of Medical Humanities, Amsterdam Public Health (APH), Amsterdam University Medical Centre, Amsterdam, Netherlands, 4Dansk Gigthospital, Sønderborg, Denmark, 5Institute of Infection, Immunity & Inflammation, University of Glasgow, Glasgow, United Kingdom, 6Leiden University Medical Center, Leiden, Netherlands, 7Northwell Health, New York, 8Rheumazentrum Ruhrgebiet-Ruhr-University Bochum, Herne, Germany, Herne, Germany, 9Sorbonne Université and Hôpital Pitié-Salpêtrière, Paris, France

    Background/Purpose: There is now an increasing range of drug options in PsA. To inform the update of the EULAR PsA management recommendations (Ref 1), we…
  • Abstract Number: 2493 • 2019 ACR/ARP Annual Meeting

    IL-6 and TNF-α Influence on Clinical Manifestations, Activity and Comorbidity in Psoriatic Arthritis Patients

    Maria Elisa Acosta1, Luis Gomez-Lechon 1, Guadalupe Manzano Canabal 1, Olga Compan 2, Cristina Hidalgo 3, Olga Martinez 1, Ana Turrión 1, Javier del Pino 1 and Carlos Montilla 1, 1Hospital Clínico Universitario de Salamanca, Salamanca, Spain, 2Hospital Clinico Universitario de Salamanca, SALAMANCA, Spain, 3Hospital Clínico Universitario de Salamanca, Salamanca, Castilla y Leon, Spain

    Background/Purpose: The activation of the Th-1 and Th-17 lymphocytes response seems to be one of the causes associated with PsA onset. During this process cytokines…
  • Abstract Number: 2494 • 2019 ACR/ARP Annual Meeting

    Comparison of Comorbidity in Spondyloarthritis: Influence on Inflammatory Activity in Patients with Psoriatic Arthritis

    Luis Gomez-Lechon1, Maria Elisa Acosta 1, Guadalupe Manzano Canabal 1, Olga Compan 1, Cristina Hidalgo 2, Olga Martinez 1, Ana Turrión 1, Javier del Pino 1 and Carlos Montilla 1, 1Hospital Clínico Universitario de Salamanca, Salamanca, Spain, 2Hospital Clínico Universitario de Salamanca, Salamanca, Castilla y Leon, Spain

    Background/Purpose: Psoriatic arthritis (PsA) is a heterogeneous disease that is included in the group of spondyloarthritis. Although PsA has its own clinical characteristics, it has…
  • Abstract Number: 2495 • 2019 ACR/ARP Annual Meeting

    Oligoarticular Psoriatic Arthritis

    Dafna Gladman1, Justine (Yang) Ye 2, Vinod Chandran 3, Ker-Ai Lee 4 and Richard Cook 5, 1Toronto Western Hospital, Toronto, Canada, Toronto, ON, Canada, 2University Health Network, University of Toronto, Toronto, ON, Canada, 3University Health Network, University of Toronto, Toronto, Canada, 4University of Waterloo, Waterloo, 5University of Waterloo, Waterloo, Canada

    Background/Purpose: Oligoarthritis, defined as ≤4 affected joints, was recognized as a pattern of psoriatic arthritis (PsA) by Moll and Wright. In some jurisdictions, patients with…
  • Abstract Number: 2496 • 2019 ACR/ARP Annual Meeting

    Serum Metabolomic Analysis of Psoriatic Arthritis Using Solid Phase Microextraction – Liquid Chromatography – High-Resolution Mass Spectrometry Identifies Putative Disease Activity Markers

    Vinod Chandran1, Nikita Looby 2, Nathaly Reyes-Garces 2, Rohan Machhar 3, Miao Yu 2, Anna Roszkowska 2, Janusz Pawliszyn 2 and Vathany Kulasingam 4, 1University Health Network, University of Toronto, Toronto, Canada, 2University of Waterloo, Waterloo, ON, Canada, 3Krembil Research Institute, University Health Network, Toronto, Canada, 4University of Toronto, Toronto, ON, Canada

    Background/Purpose: Disease activity in psoriatic arthritis (PsA) is often difficult to assess but drives treatment decisions, joint damage and long-term outcomes. We aimed to identify…
  • Abstract Number: 2497 • 2019 ACR/ARP Annual Meeting

    Description and Prevalence of Spondyloarthritis in Unselected Patients with Psoriasis, Acute Anterior Uveitis, and Inflammatory Bowel Disease Presenting with Undiagnosed Back Pain

    Walter P. Maksymowych1, Raj Carmona 2, Jonathan Chan 3, James Yeung 4, Sibel Zehra Aydin 5, Liam Martin 6, Ariel Masetto 7, Dianne Mosher 8, Olga Ziouzina 6, Stephanie Keeling 9, Sherry Rohekar 10, Rana Dadashova 11, Joel Paschke 11, Amanda Carapellucci 11 and Robert Lambert 12, 1University of Alberta/CARE ARTHRITIS, Edmonton, AB, Canada, 2McMaster University, Hamilton, Canada, 3Artus Health Clinic, Vancouver, BC, Canada, 4Yeung Rheumatology, Vancouver, Canada, 5University of Ottawa Faculty of Medicine, Rheumatology,Ottawa Hospital Research Institute, 1967 Riverside Drive, Ottawa, ON, K1H 7W9, CANADA, Ottawa, Canada, 6University of Calgary, Calgary, Canada, 7Université de Sherbrooke, Sherbrooke, QC, Canada, 8University of Calgary, Calgary, AB, Canada, 9University of Alberta, Edmonton, AB, Canada, 10Western University, London, ON, Canada, 11CARE Arthritis, Edmonton, Canada, 12University of Alberta, Edmonton, Canada

    Background/Purpose: There is limited prospective data as to the frequency of axial spondyloarthritis (axSpA) in unselected patients referred to rheumatologists with undiagnosed back pain who…
  • Abstract Number: 2498 • 2019 ACR/ARP Annual Meeting

    Incidence and Predictors of Heart Failure in Patients with Psoriatic Disease – a Cohort Study

    Sahil Koppikar1, Keith Colaco 2, Paula Harvey 3, Vinod Chandran 4, Dafna Gladman 5, Richard Cook 6 and Lihi Eder 7, 1University of Toronto, Markham, ON, Canada, 2University of Toronto, Women's College Hospital, University Health Network, Toronto, ON, Canada, 3Women's College Hospital, Toronto, ON, Canada, 4University Health Network, University of Toronto, Toronto, Canada, 5Toronto Western Hospital, Toronto, Canada, Toronto, ON, Canada, 6University of Waterloo, Waterloo, Canada, 7Women’s College Hospital and the Department of Medicine, University of Toronto, Toronto, Canada

    Background/Purpose: Data about heart failure (HF) in patients with psoriatic disease (PsD) are sparse. The aims of the study were to: 1) determine the incidence…
  • Abstract Number: 2499 • 2019 ACR/ARP Annual Meeting

    Predicting Risk of Developing Psoriatic Arthritis (PsA) in Siblings of Patients with Psoriatic Arthritis

    Winifred Badaiki1, Quan Li 2, Tanya Burry 1, Fiona Landells 1, Rachel Gehue 1, Cindy Penney 3, DIanne Codner 1, Amanda Dohey 1, Kerri Smith 1, Fatima Abji 4, Dafna Gladman 5, Darren O'Rielly 1, Vinod Chandran 6 and Proton Rahman 7, 1Memorial University, St. Johns, Canada, 2Toronto Western Hospital, Toronto, Canada, 3Memorial University, St Johns, Canada, 4Memorial University, Toronto, Canada, 5Toronto Western Hospital, Toronto, Canada, Toronto, ON, Canada, 6University Health Network, University of Toronto, Toronto, Canada, 7Memorial University, St. Johns, NL, Canada

    Background/Purpose: Delay in diagnosis of psoriatic arthritis (PsA) has been shown to contribute to poor radiographic and functional outcome and less successful response to treatment…
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