Abstracts Archive - Page 871 of 2425 - ACR Meeting Abstracts

Abstract Number: 1689 • 2019 ACR/ARP Annual Meeting
Off-Label Use of Biotherapies to Treat Relapsing And/or Refractory Polyarteritis Nodosa
Alice Canzian ¹, Omer Karadag ², Anne Contis ³, François Maurier ⁴, Silvia Sartorelli ⁵, Laure Denis ⁶, Sébastien Sanges ⁷, Claire de Moreuil ⁸, Cécile-Audrey Durel ⁹, Stéphane Durupt ¹⁰, Marie Jachiet ¹¹, Diane Rouzaud ¹², Carlo Salvarani ¹³, Franco Schiavon ¹⁴, Lorenzo Dagna ¹⁵, Fabrice Bonnet ¹⁶, David Jayne ¹⁷, Loic Guillevin ¹⁸ and Benjamin Terrier¹, ¹Cochin Hospital, Paris, France, ²Hacettepe University Vasculitis Centre, Ankara, Turkey / Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, UK, Ankara, Turkey, ³Department of Internal Medicine and Clinical Immunology , Hôpital Saint-André, CHU de Bordeaux , Bordeaux , France, Bordeaux, France, ⁴Service de Médecine Interne, Hôpital Belle Isle, Metz, Metz, France, ⁵Vita-Salute San Raffaele University, IRCCS San Raffaele Hospital, Milan, Italy, ⁶Clermont-Ferrand Hospital, Clermont-Ferrand, France, ⁷CHRU Lille, Lille, France, ⁸CHU Brest, Brest, France, ⁹Department of Internal Medicine, Hôpital Edouard Herriot, Lyon, France, Lyon, France, ¹⁰Lyon Hospital, Lyon, France, ¹¹Saint Louis Hospital, Paris, France, ¹²Bichat Hospital, Paris, France, ¹³Division of Rheumatology, Arcispedale Santa Maria Nuova-IRCCS, Reggio Emilia, Italy, ¹⁴Operative Unit of Rheumatology, Department of Medicine DIMED, University of Padova, Padova, Italy, Padova, Italy, ¹⁵Unit of Immunology, Rheumatology, Allergy and Rare Diseases (UnIRAR), IRCCS San Raffaele Hospital, Vita-Salute San Raffaele University, Milan, Italy, ¹⁶CHU Bordeaux, Bordeaux, France, ¹⁷Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, UK, Cambridge, United Kingdom, ¹⁸National Referral Center for Rare Systemic Autoimmune Diseases Paris Cochin, Paris, France
Background/Purpose: Polyarteritis nodosa (PAN) is a rare systemic necrotizing vasculitis of medium- and small-sized arteries, not associated with antineutrophil cytoplasmic antibodies (ANCA). Conventional treatments include…
Abstract Number: 1690 • 2019 ACR/ARP Annual Meeting
The Long-term Outcome of Patients with Arthritis of Behçet’s Disease
Hirotoshi Kikuchi¹, Takafumi Tomizuka ¹, Kurumi Asako ¹, Hajime Kono ¹ and Shunsei Hirohata ², ¹Teikyo University School of Medicine, Tokyo, Japan, ²Nobuharra Hospital & Institute of Biomechanics, Tokyo, Japan
Background/Purpose: Behçet’s disease (BD) is characterized by recurrent aphthous stomatitis, eye lesions, skin lesions, and genital ulcer. In addition to these symptoms, Behçet’s disease is…
Abstract Number: 1691 • 2019 ACR/ARP Annual Meeting
Efficacy of TNF α Inhibitors for Refractory Vascular Behcet’s Disease: A Multicenter Observational Study of 27 Patients
Aysun Aksoy ¹, Ayten Yazici ², Ahmet Omma ³, Ayşe Cefle ⁴, Fatos Onen ⁵, Unal Tasdemir ⁶, Tulin Ergun ⁷, Haner Direskeneli ⁸ and Fatma Alibaz-Oner⁹, ¹Marmara University Faculty of Medicine, Division of Internal Medicine, Department of Rheumatology, Istanbul, Turkey; University of Manchester, Division of Musculoskeletal and Dermatological Sciences, Manchester, United Kingdom, Istanbul, Istanbul, Turkey, ²Kocaeli University, Faculty of Medicine, Division of Rheumatology, Kocaeli, Kocaeli, Turkey, ³Health Sciences University, Ankara Numune Training and Research Hospital, Department of Rheumatology, Ankara, Turkey, ⁴Division of Rheumatology, Kocaeli University School of Medicine, Kocaeli, Turkey, Kocaeli, Turkey, ⁵Dokuz Eylul University School of Medicine, Division of Rheumatology, İzmir, Turkey, ⁶Dokuz Eylul University, School of Medicine Division of Internal Medicine Rheumatology Department, izmir, Turkey, ⁷Marmara University School of Medicine Dermatology Department, istanbul, Turkey, ⁸Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey, ⁹Marmara University Faculty of Medicine,Department of Rheumatology,Istanbul,Turkey, Istanbul, Turkey
Background/Purpose: Vascular involvement is one of the major causes of morbidity and mortality in Behcet’s Disease (BD) patients. Immunosuppressive (IS) agents are the mainstay of…
Abstract Number: 1692 • 2019 ACR/ARP Annual Meeting
Long-Term Follow-Up of Anti-IL6-Receptor Tocilizumab in Refractory Uveitis in Patients with Behçet Disease: Multicenter Study of 14 Patients in Clinical Practice
Iñigo Gonzalez-Mazon¹, Lara Sanchez-Bilbao ², Belén Atienza-Mateo ², Jose Luis Martín-Varillas ², DIANA PRIETO- PENA ¹, Vanesa Calvo-Río ³, Rosalia Demetrio ⁴, Natalia Palmou-Fontana ¹, Javier Loricera ⁵, Emma Beltrán Catalán ⁶, Marisa Hernández Garfella ⁷, Elia Valls-Pascual ⁸, Antonio Atanés ⁹, Miguel Cordero Coma ⁹, Joan M Nolla ¹⁰, Carmen carrasco-Cubero ¹¹, Julio Sánchez ¹², Miguel A Gonzalez-Gay ² and Ricardo Blanco ², ¹Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ²Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, ³Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ⁴Hospital Universitario Marqués de Valdecilla, Santander, Spain, ⁵H.U. Marques de Valdecilla, Santander, Spain, ⁶Hospital del Mar, Barcelona, Spain, ⁷H.G.U. Valencia, Valencia, ⁸Dr Peset University Hospital, Valencia, Spain, ⁹HUAC La Coruña, Coruña, Spain, ¹⁰Hospital Universitari de Bellvitge, Hospitalet, Spain, ¹¹CHU de Badajoz, Badajoz, Spain, ¹²Hospital 12 de Octubre, Madrid, Spain
Background/Purpose: Ocular involvement in Behçet’s disease (BD) is a potential severe and disabling complication. Anti-TNF-α agents have shown an improvement of visual outcome in BD-related…
Abstract Number: 1693 • 2019 ACR/ARP Annual Meeting
Biological Therapy in Neurobehçet: Multicenter Study of 31 Patients
Iñigo Gonzalez-Mazon¹, Lara Sanchez-Bilbao ², Jose Luis Martín-Varillas ², Belén Atienza-Mateo ², Vanesa Calvo Río ², Santos Castañeda ³, Esther Vicente-Rabaneda ⁴, Olga Maiz ⁵, ana blanco ⁵, Clara Moriano ⁶, Elvira Díez ⁶, JL Andreu ⁷, Concepción Delgado-Beltrán ⁸, Marta Loredo-Martinez ⁸, Javier Narváez ⁹, Angel Ramos-Calvo ¹⁰, Francisca Sivera ¹¹, E. Raya ¹², Norberto Ortego Centeno ¹², Jose luis callejas rubio ¹², Anahy Brandy-Garcia ¹³, Alejandro Olivé-Marqués ¹⁴, Sabela Fernández ¹⁵, Ricardo Gómez De La Torre ¹⁶, Iñaki Torre-Salaberri ¹⁷, Julio Sanchez ¹⁸, A. Urruticoechea-Arana ¹⁹, Eva salgado-Pérez ²⁰, Rafael Melero ²¹, Olga Martinez ²², Susana Romero-Yuste ²³, Miguel A Gonzalez-Gay ² and Ricardo Blanco ², ¹Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ²Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, ³Rheumatology, Hospital Universitario La Princesa, Madrid, Madrid, Spain, ⁴Rheumatology Department, Hospital Universitario La Princesa, Madrid, Spain, ⁵Rheumatology, Hospital Universitario Donostia, san sebastian, Pais Vasco, Spain, ⁶Complejo Asistencial Universitario de León, León, Castilla y Leon, Spain, ⁷HU Puerta del Hierro, Madrid, ⁸H. Clinico Lozano Blesa Zaragoza, Zaragoza, Aragon, Spain, ⁹Rheumatology Department, Hospital Universitari de Bellvitge, Barcelona, Catalonia, Spain, ¹⁰Rheumatology, Complejo Hospitalario de Soria, soria, Castilla y Leon, Spain, ¹¹Hospital General Universitario de Elda, Elda, Spain, ¹²Hospital San Cecilio, Granada, Andalucia, Spain, ¹³Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ¹⁴Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain, ¹⁵Hospital Universitario San Agustín, Avilés, Asturias, Spain, ¹⁶Department of Internal Medicine, Hospital Universitario Central de Asturias, Oviedo, Spain, Oviedo, Spain, ¹⁷BASURTO UNIVERSITY HOSPITAL, Bilbao, Spain, ¹⁸H. 12 de Octubre, Madrid, Spain, ¹⁹HU Can Misses, Ibiza, Spain, ²⁰Complejo Hospitalario Universitario de Ourense, Ourense, Galicia, Spain, ²¹Complexo Hospitalario Universitario de Vigo, Vigo, Galicia, Spain, ²²Hospital Clínico Universitario de Salamanca, Salamanca, Spain, ²³Complejo Hospitalario Universitario Pontevedra, Pontevedra, Galicia, Spain
Background/Purpose: Behçet's disease (BD) is a variable vessel vasculitis and typically presents with mucocutaneous involvement. However, any organ can be affected, being the neurological affectation…
Abstract Number: 1694 • 2019 ACR/ARP Annual Meeting
Pharmacogenetics and Pharmacodynamics of Response to Apremilast in a Phase 3 Clinical Study in Subjects with Active Behçet’s Disease
Joseph Maranville¹, Irina Medvedeva ¹, Robert Yang ¹, Mindy Chen ², Lorraine (Ruoying) Fang ², Sandra Collazo ³, Shannon McCue ³, Marla Hochfeld ³ and Peter Schafer ³, ¹Celgene Corporation, Cambridge, MA, ²Celgene Corporation, Berkeley Heights, NJ, ³Celgene Corporation, Summit, NJ
Background/Purpose: This was an exploratory analysis of genetic polymorphisms, plasma biomarkers, and blood leukocytes with clinical response in the phase 3 clinical study CC-10004-BCT-002 (NCT02307513).Methods:…
Abstract Number: 1695 • 2019 ACR/ARP Annual Meeting
Apremilast in Combination vs Monotherapy for Refractory Oral And/or Genital Ulcers in Behçet’s Disease: National Multicenter Study of 51 Cases
Belén Atienza-Mateo¹, Mónica Calderón-Goercke ², DIANA PRIETO- PENA ³, Iñigo Gonzalez-Mazon ³, Lara Sanchez-Bilbao ¹, Jose Luis Martín-Varillas ¹, Javier Loricera ⁴, Vanesa Calvo Río ¹, Jenaro Graña ⁵, Gerard Espinosa ⁶, Clara Moriano ⁷, Trinidad Pérez-Sandoval ⁷, Manuel Martín-Martínez ⁷, Elvira Díez ⁷, María Dolores García-Armario ⁸, Esperanza Martínez ⁸, Ivan Castellvi ⁹, Patricia Moya Alvarado ¹⁰, Francisca Sivera ¹¹, Jaime Calvo-Alen ¹², Isabel de la Morena ¹³, Francisco Ortiz-Sanjuán ¹⁴, José Andrés Román-Ivorra ¹⁴, Ana Pérez-Gómez ¹⁵, Sergi Heredia ¹⁶, Alejandro Olivé-Marqués ¹⁶, Águeda Prior-Español ¹⁷, Carolina Díez ¹⁸, Juan José Alegre-Sancho ¹⁹, Amparo Ybáñez ¹⁹, Ángels Martínez-Ferrer ¹⁹, Javier Narváez ²⁰, Ignasi Figeras ²¹, Ana Turrión ²², Susana Romero-Yuste ²³, Pilar Trénor ²⁴, Soledad Ojeda ²⁵, Miguel Á. González-Gay ²⁶ and Ricardo Blanco ²⁶, ¹Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Spain, ²Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ³Rheumatology, Hospital Universitario Marques de Valdecilla, Santander, Cantabria, Spain, ⁴Rheumatology Department. Hospital Marqués de Valdecilla, Santander, Cantabria, Spain, ⁵Centro Médico Quirón A Coruña, A Coruña, Galicia, Spain, ⁶Department of Autoimmune Diseases, Hospital Clínic, Barcelona, Barcelona, Catalonia, Spain, ⁷Complejo Asistencial Universitario de León, León, Castilla y Leon, Spain, ⁸Hospital Lluís Alcanyís, Xàtiva, Comunidad Valenciana, Spain, ⁹Hospital de la Santa Creu i Sant Pau, Barcelona, Spain, ¹⁰Hospital de la Santa Creu i Sant Pau, Barcelona, Catalonia, Spain, ¹¹Hospital General Universitario de Elda, Elda, Spain, ¹²Hospital Universitario Araba, Vitoria-Gasteiz, Spain, ¹³Hospital General Universitario de Valencia, Valencia, Comunidad Valenciana, Spain, ¹⁴Hospital Universitario y Politécnico La Fe, Valencia, Comunidad Valenciana, Spain, ¹⁵Hospital Universitario Príncipe de Asturias, Alcalá de Henares, Madrid, Spain, ¹⁶Hospital Universitari Germans Trias i Pujol, Badalona, Catalonia, Spain, ¹⁷Hospital Universitari Germans Trias i Pujol, Badalona, Spain, ¹⁸Hospital de El Bierzo, León, Castilla y Leon, Spain, ¹⁹Hospital Universitario Doctor Peset, Valencia, Comunidad Valenciana, Spain, ²⁰Rheumatology Department, Hospital Universitari de Bellvitge, Barcelona, Catalonia, Spain, ²¹Hospital Bellvitge, Barcelona, Catalonia, Spain, ²²Hospital Clínico Universitario de Salamanca, Salamanca, Spain, ²³Complejo Hospitalario Universitario Pontevedra, Pontevedra, Galicia, Spain, ²⁴Hospital Clínico Universitario de Valencia, Valencia, Comunidad Valenciana, Spain, ²⁵Hospital Doctor Negrín, Las Palmas de Gran Canaria, Canarias, Spain, ²⁶Hospital Universitario Marqués de Valdecilla, Santander, Cantabria, Spain
Background/Purpose: Oral and/or genital aphthous ulcers are the most common symptoms of Behçet´s disease (BD), and are often refractory to conventional treatment. The inhibitor of…
Abstract Number: 1696 • 2019 ACR/ARP Annual Meeting
Is the Risk of Tuberculosis Increased in Behçet’s Disease Compared to Other Rheumatological Disorders After Anti-TNF-α Treatment?
Ummugulsum Gazel ¹, Derya Kocakaya ², Irem Topcu ³, Hakan Karatas ⁴, Murat Karabacak ⁵, Pamir Atagunduz ⁶, Nevsun Inanc ⁷, Fatma Alibaz-Oner ⁵ and Haner Direskeneli⁸, ¹Marmara University, Faculty of Medicine, Department of Rheumatology, Istanbul, Turkey, Istanbul, Turkey, ²Marmara University Faculty of Medicine Department of Chest Diseases, Istanbul, Turkey, Istanbul, Istanbul, Turkey, ³Marmara University, School of Medicine, Istanbul,Turkey, ıstanvul, Turkey, ⁴Marmara University ,School of Medicine, Istanbul,Turkey, Istanbul, Turkey, ⁵Marmara University Faculty of Medicine,Department of Rheumatology,Istanbul,Turkey, Istanbul, Turkey, ⁶Marmara University Faculty of Medicine,Department of Rheumatology, Istanbul, Turkey, Istanbul, Turkey, ⁷Marmara University, Faculty of Medicine, Division of Rheumatology, Istanbul, Turkey, ISTANBUL, Turkey, ⁸Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey
Background/Purpose: Tumor necrosis factor (TNF)-α inhibitors are extensively utilized in the treatment of inflammatory rheumatic diseases. These agents increase the risk of tuberculosis (TB), especially…
Abstract Number: 1697 • 2019 ACR/ARP Annual Meeting
Efficacy of Apremilast for Oral Ulcers Associated with Active Behçet’s Syndrome over 64 Weeks: Long-term Results from the Japanese Subgroup in a Phase III Study
Mitsuhiro Takeno¹, Yoshiya Tanaka ², Hajime Kono ³, Shoji Sugii ⁴, Mitsumasa Kishimoto ⁵, Sue Cheng ⁶, Shannon McCue ⁷, Mindy Chen ⁸, Maria Paris ⁶ and Hiroaki Dobashi ⁹, ¹Nippon Medical School, Tokyo, Japan, ²University of Occupational and Environmental Health Japan, Kitakyushu, Japan, ³Teikyo University School of Medicine, Tokyo, Japan, ⁴Department of Rheumatic Diseases, Tokyo Metropoitan Tama Medica Center, Fuchu, Japan, ⁵Immuno-Rheumatology Center, St. Luke’s International Hospital, Tokyo, Japan, ⁶Celgene Corporation, Summit, ⁷Celgene Corporation, Summit, NJ, ⁸Celgene Corporation, Berkeley Heights, NJ, ⁹Kagawa University, Kagawa, Japan
Background/Purpose: Behçet’s syndrome is a chronic, multi-system, variable vessel vasculitis characterized by painful, recurrent oral ulcers (OU) that can be disabling and may impair quality…
Abstract Number: 1698 • 2019 ACR/ARP Annual Meeting
Development of Machine Learning Models (Artificial Neural Networks) for Prediction of Vision Threatening Behçet’s Disease
Nevin Hammam¹, Eiman Abd El-Latif ², Iman I El-Gazzar ³, Nermeen Samy ⁴, Rasha A Abdel Noor ⁵, Emad El-Shebeiny ⁶, Amany R El-Najjar ⁷, Nahla N Eesa ⁸, Mohamed N Salem ⁹, Soha E Ibrahim ¹⁰, Dina F El-Essawi ¹¹, Ahmed M Elsaman ¹², Hanan M Fathi ¹³, Rehab A Sallam ¹⁴, Rawhya R El-Shereef ¹⁵, Mervat I Abd-Elazeem ¹⁶, Emtethal A Said ¹⁷, Noha M Khalil ¹⁸, Dina Shahin ¹⁹, Hanan M El-Saadany ²⁰, Marwa S ElKhalifa ²¹, Samah I Nasef ²², Ahmed M Abdalla ²³, Nermeen Noshy ⁴, Rasha M Fawzy ²⁴, Ehab Saad ²⁵, Abdel-Hafeez Moshrif ²⁶, Amira T El-Shanawany ²⁷, Yousra H Abdel-Fattah ²⁸, Hossam M Khalil ²⁹ and Tamer A Gheita ³⁰, ¹University of Alberta, Edmonton, AB, Canada, ²Ophthalmology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt, Alexandria, Egypt, ³Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ⁴Internal Medicine Department, Rheumatology Unit, Faculty of Medicine, Ain-Shams University, Cairo, Egypt, Cairo, Egypt, ⁵Internal Medicine Department, Rheumatology Unit, Tanta University, Gharbia, Egypt, Gharbia, Egypt, ⁶Internal Medicine Department, Rheumatology Unit, Menoufia University, Menoufia, Egypt, Menoufia, Egypt, ⁷Rheumatology Department, Faculty of Medicine, Zagazig University, Sharkia, Egypt, Sharkia, Egypt, ⁸Rheumatology Department, Faculty of Medicine, Cairo University, Cairo, Egypt., Cairo, Egypt, ⁹Internal Medicine Department, Rheumatology Unit, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt, Beni-Suef, Egypt, ¹⁰Rheumatology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt, Cairo, Egypt, ¹¹Internal Medicine Department, Rheumatology Unit (NCRRT), Atomic Energy Authority (AEA), Cairo, Egypt, Cairo, Egypt, ¹²Rheumatology Department, Faculty of Medicine, Sohag University, Sohag, Egypt., Sohag, Egypt, ¹³Rheumatology Department, Faculty of Medicine, Fayoum University, Fayoum, Egypt, Fayoum, Egypt, ¹⁴Rheumatology Department, Faculty of Medicine, Mansoura University, Dakahlia, Egypt, Dakahlia, Egypt, ¹⁵Rheumatology Department, Faculty of Medicine, Minia University, Minia, Egypt., Minia, Egypt, ¹⁶Rheumatology Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt, Beni-Suef, Egypt, ¹⁷Rheumatology Department, Faculty of Medicine, Benha University, Kalubia, Egypt, Benha, Egypt, ¹⁸Internal Medicine Department, Rheumatology Unit, Faculty of Medicine, Cairo University, Cairo, Egypt, Cairo, Egypt, ¹⁹Internal Medicine Department, Rheumatology Unit, Faculty of Medicine, Mansoura University, Dakahlia, Egypt, Dakahlia, Egypt, ²⁰Rheumatology Department, Faculty of Medicine, Tanta University, Tanta, Egypt, Tanta, Egypt, ²¹Internal Medicine Department, Rheumatology Unit, Faculty of Medicine, Alexandria University, Alexandria, Egypt, Alexandria, Egypt, ²²Rheumatology Department, Faculty of Medicine, Suez-Canal University, Ismailia, Egypt, Ismailia, Egypt, ²³Rheumatology Department, Faculty of Medicine, Aswan University, Aswan, Egypt, Aswan, Egypt, ²⁴Rheumatology Department, Faculty of Medicine, Benha University, Kalubia, Egypt, Kalubia, Egypt, ²⁵Rheumatology Department, Faculty of Medicine, South Valley University, Qena, Egypt, Qena, Egypt, ²⁶Rheumatology Department, Faculty of Medicine, Al-Azhar University, Assuit, Egypt, Assiut, Egypt, ²⁷Rheumatology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt, Menoufia, Egypt, ²⁸Rheumatology Department, Faculty of Medicine, Alexandria University, Alexandria, Egypt, Alexandria, Egypt, ²⁹Ophthalmology Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt., Beni-Suef, Egypt, ³⁰Rheumatology Department, Kasr Al Ainy School of Medicine, Cairo University, Cairo, Egypt., Cairo, Egypt
Background/Purpose: Ocular involvement in Behçet’s Disease (BD) is associated with chronic damage and high morbidity; however, limited evidence is available on risk factors to recognize…
Abstract Number: 1699 • 2019 ACR/ARP Annual Meeting
Disease Course of Behçet’s Syndrome Patients Not Fulfilling International Study Group Criteria at Presentation
Sinem Nihal Esatoglu¹, Seyda Bilgin ², Cem Sulu ², Vedat Hamuryudan ³, Zekayi Kutlubay ⁴, Melike Melikoglu ³, Izzet Fresko ⁵, Hasan Yazici ⁶ and Gulen Hatemi ⁷, ¹Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul, Turkey, ²Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Istanbul, Turkey, ³Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University – Cerrahpasa, Behçet’s Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, ⁴Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Dermatology, Istanbul University – Cerrahpasa, Behçet’s Disease Research Center, Istanbul, Turkey, Istanbul, Turkey, ⁵Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University – Cerrahpasa, Behçet’s Disease Research Center, Istanbul, Turkey, ⁶Academic Hospital, Istanbul, Turkey, Istanbul, Turkey, ⁷Istanbul University-Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, Istanbul University-Cerrahpasa, Behcet's Disease Research Center, Istanbul, Turkey, Istanbul, Turkey
Background/Purpose: Behçet’s syndrome (BS) shows a heterogeneous phenotype involving many organ systems and is diagnosed by recognizing the coexisting manifestations. Patients may have major organ…
Abstract Number: 1700 • 2019 ACR/ARP Annual Meeting
Clinical Characteristics and the Level Disease Activity of Behcet´s Disease in China: A Study Based on Smart System of Disease Management (SSDM)
Lingli Dong¹, Shouxin Li ¹, Fen Wang ², Zhenbiao Wu ³, Shengtao Zhang ¹, Qin Li ⁴, Henglian Wu ⁵, Zhengang Wang ⁶, Huifang Guo ⁷, Yikai Yu ¹, LingXun Shen ⁸, Yasong Li ⁹, Yang Liu ¹⁰, Tian Wang ¹¹, Peng Ji ¹², Zongwen Shuai ², Hongbin Li ¹³, Li Luo ¹², Hui Xiao ¹⁴, Yuhua Jia ¹⁵, Bing Wu ¹⁶, Shengsong Jia ¹⁵, Fei Xiao ¹⁷ and Lijun Wu ¹⁸, ¹Tongji Hospital，Tongji Medical Colllege，Huazhong University of Science and Technology, Wuhan, Hubei, China (People's Republic), ²First Affiliated Hospital of Medical University Of Anhui, Hefei, Anhui, China (People's Republic), ³The First Affiliated Hospital of The Fourth Military Medical University, Xian, Shanxi, China (People's Republic), ⁴The First People's Hospital of Yunnan Province, Kunming, Yunnan, China (People's Republic), ⁵Dongguan donghua hospital, Dongguan, Guangdong, China (People's Republic), ⁶TongRen hospital,Capital University, Bei Jing, China (People's Republic), ⁷The Second Hospital of Hebei Medical University, Shijiazhuang, Hebei, China (People's Republic), ⁸Union Hospital Affiliated Tongji Medical College of Huazhong University of Science and Technology, Wuhan, China (People's Republic), ⁹Zhejiang provincial people's hospital, Hangzhou, Zhejiang, China (People's Republic), ¹⁰Affiliated Hospital of Inner Mongolia Medical University, Huhehaote, Nei Mongol, China (People's Republic), ¹¹Beijing Anzhen Hospital, Capital Medical University, Beijing, Beijing, China (People's Republic), ¹²The first affiliated hospital of xinjiang medical university, Urumchi, China (People's Republic), ¹³The Affiliated Hospital of Inner Mongolia Medical University, Huhhot, Nei Mongol, China (People's Republic), ¹⁴Shanghai Gothic Internet Technology Co., Ltd, shanghai, Shanghai, China (People's Republic), ¹⁵Shanghai Gothic Internet Technology Co., Ltd., Shanghai, Shanghai, China (People's Republic), ¹⁶Shanghai Gothic Internet Technology Co., Ltd, Shanghai, China (People's Republic), ¹⁷Shanghai Gothic Internet Technology Co., Ltd., shanghai, China (People's Republic), ¹⁸People's Hospital of Xinjiang Uygur Autonomous region, Wulumuqi, Xinjiang, China (People's Republic)
Background/Purpose: Behcet´s disease (BD) is a systemic autoimmune disease that affects multiple organ systems with recurrent oral ulcers, genital ulcers and skin lesions, which might…
Abstract Number: 1701 • 2019 ACR/ARP Annual Meeting
Amyloidosis in Behcet’s Disease: Experience of a Vasculitis Centre at Silk Road
Ertugrul Cagri Bolek ¹, Enes Erul ¹, Gozde Kubra Yardımcı ¹, Levent Kilic ², Ali Akdoğan ¹ and Omer Karadag³, ¹Hacettepe University Vasculitis Centre, Ankara, Turkey, ankara, Turkey, ²Hacettepe University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Ankara, Turkey, ³Hacettepe University Vasculitis Centre, Ankara, Turkey / Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, UK, Ankara, Turkey
Background/Purpose: Bechet’s disease (BD) is a vasculitis characterized by oral aphtae, genital ulcers, skin lesions, uveitis and with less frequent involvement of the neurological, vascular…
Abstract Number: 1702 • 2019 ACR/ARP Annual Meeting
Target Organ Associations in Polyarteritis Nodosa (PAN): Results of a Worldwide Collaboration Study
Omer Karadag¹, Shunsuke Furuta ², Alojzija Hocevar ³, Ummugulsum Gazel ⁴, Andrea Hinojosa-Azaola ⁵, Serdal Ugurlu ⁶, Seerapani Gopaluni ⁷, Ertugrul Cagri Bolek ⁸, Berkan Armagan ⁹, Fatma Alibaz-Oner ¹⁰, Matija Tomšič ¹¹, Gizem Ayan ¹², Ayten Yazici ¹³, Eduardo Martin-Nares ¹⁴, Susy Marcela Sánchez-Cubías ⁵, Mehmet Nedim Tas ¹⁵, Ayşe Cefle ¹⁶, Kenan Aksu ¹⁷, Hajime Kono ¹⁸, Tamihiro Kawakami ¹⁹, Yoshiyuki Abe ²⁰, Timuçin Kaşifoğlu ²¹, Mehmet Engin Tezcan ²², Onay Gercik ²³, Sadettin Kilickap ²⁴, Haner Direskeneli ²⁵, Seza Ozen ²⁶, Ali İhsan Ertenli ⁸ and David Jayne ⁷, ¹Hacettepe University Vasculitis Centre, Ankara, Turkey / Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, UK, Ankara, Turkey, ²Department of Alergy and Immunology, Chiba University Hospital, Chiba, Japan, Chiba, Japan, ³Department of Rheumatology, University Medical Center Ljubljana, Slovenia, LJUBLJANA, Slovenia, ⁴Marmara University, Faculty of Medicine, Department of Rheumatology, Istanbul, Turkey, Istanbul, Turkey, ⁵Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico., Mexico City, Mexico, ⁶Istanbul University - Cerrahpasa, Cerrahpasa Medical Faculty, Department of Internal Medicine, Division of Rheumatology, istanbul, Turkey, ⁷Vasculitis and Lupus Clinic, Addenbrooke’s Hospital, University of Cambridge, UK, Cambridge, United Kingdom, ⁸Hacettepe University Vasculitis Centre, Ankara, Turkey, ankara, Turkey, ⁹Department of Internal Medicine, Hacettepe University, Faculty of Medicine, Ankara, Turkey., Ankara, Turkey, ¹⁰Marmara University Faculty of Medicine,Department of Rheumatology,Istanbul,Turkey, Istanbul, Turkey, ¹¹Department of Rheumatology, University Medical Centre Ljubljana, Ljubljana, Slovenia, LJUBLJANA, Slovenia, ¹²University of Ottawa Faculty of Medicine, Rheumatology, Ottawa, ON, Canada, ¹³Kocaeli University, Faculty of Medicine, Division of Rheumatology, Kocaeli, Kocaeli, Turkey, ¹⁴Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico, ¹⁵Ege University, Faculty of Medicine, Department of Rheumatology, Izmir, Turkey, Izmir, Turkey, ¹⁶Division of Rheumatology, Kocaeli University School of Medicine, Kocaeli, Turkey, Kocaeli, Turkey, ¹⁷Ege University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, İzmir, Turkey, ¹⁸Teikyo University School of Medicine, Tokyo, Japan, ¹⁹Department of Dermatology, Tohoku Medical and Pharmaceutical University, Japan, Tohoku, Japan, ²⁰Department of Rheumatology, Juntendo University, Tokyo, Japan, Tokyo, Japan, ²¹Eskişehir Osmangazi University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, Eskişehir, Turkey, ²²Department of Rheumatology, Kartal Dr. Lutfi Kirdar Training and Research Hospital , Istanbul, Turkey, Istanbul, Turkey, ²³Izmir Katip Celebi University, Faculty of Medicine, Department of Internal Medicine, Division of Rheumatology, İzmir, Turkey, ²⁴Hacettepe University, Faculty of Medicine, Department of Preventive Oncology, Ankara, Turkey, Ankara, Turkey, ²⁵Marmara University, School of Medicine, Division of Rheumatology, Istanbul, Turkey, ²⁶Hacettepe University Hospital, Ankara, Turkey
Background/Purpose: Polyarteritis nodosa (PAN) is a rare type of the systemic vasculitides with heterogeneous presentations.There is a paucity of information on the current phenotypes, ethnic and…
Abstract Number: 1703 • 2019 ACR/ARP Annual Meeting
Increased Levels of IL-2 and IL-4 Promote Th17/Treg Immune Imbalance in Patients with Behcet’s Disease
Yue Liu¹, Yan Yang ¹, Rui Su ², Xinyu Zheng ³, Xiao-feng Li ⁴ and Cai-hong Wang ⁵, ¹Department of Rheumatology, the Second Hospital of Shanxi Medical University, Taiyuan, Shanxi, China (People's Republic), ²Department of Rheumatology, the Second Hospital of Shanxi Medical University, Tai yuan, Shanxi, China (People's Republic), ³Department of Rheumatology, the Second Hospital of Shanxi Medical University, Taiyuan , Shanxi, China, Tai Yuan, China (People's Republic), ⁴The Second Hospital of Shanxi Medical University, Taiyuan, China (People's Republic), ⁵The Second Hospital of Shanxi Medical University, Tai Yuan, China (People's Republic)
Background/Purpose: Behcet’s disease(BD) is a multisystem inflammatory disorder of unknown etiology.Improved understandings indicate the Th17/Treg immune imbalance may play a critical role in BD's pathogenesis,…

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