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  • Abstract Number: 0446 • ACR Convergence 2025

    A Balancing Act: The Interplay Between Resilience and Frailty in Rheumatoid Arthritis

    Hannah Brubeck1, Kylie Riggles1, Adrienne Tanus1, Nadine El-ayache2, George Mount2, Elizabeth Wahl2, Courtney Loecker3, Jose Garcia4, Dolores Shoback5, Joshua Baker6, Patti Katz7, Ariela Orkaby8 and Katherine Wysham9, 1VA Puget Sound Health Care System, Seattle, WA, 2VA Puget Sound Health Care System & University of Washington, Seattle, WA, 3University of Nebraska Medical Center, Omaha, 4VA Puget Sound Health Care System, VA GRECC, and University of Washington, Seattle, WA, 5San Francisco VA Medical Center & University of California San Francisco, San Francisco, CA, 6University of Pennsylvania, Philadelphia, PA, 7UCSF, San Rafael, CA, 8VA Boston Healthcare System & Division of Aging, Brigham and Women’s Hospital, Harvard Medical School & VA Geriatrics Research Education and Clinical Center, Boston, MA, 9VA PUGET SOUND/UNIVERSITY OF WASHINGTON, Seattle, WA

    Background/Purpose: Frailty, a state of decreased physiological reserve and heightened vulnerability to stressors, occurs prematurely in rheumatoid arthritis (RA) and is associated with poor health…
  • Abstract Number: 0252 • ACR Convergence 2025

    Capillaroscopic Signatures in Autoimmune Rheumatic Diseases: Unveiling Patterns in Systemic Sclerosis, Polyautoimmunity, and PAH

    María Paula Carrillo1, Juan Esteban Bedoya-Loaiza1, Claudia Ibáñez-Antequera1, Laura Gallego1, Alejandro Escobar1, Adriana Rojas-Villarraga2 and Jairo Cajamarca-Baron3, 1Fundacion universitaria de ciencias de la salud, Bogota, Distrito Capital de Bogota, Colombia, 2Fundacion Universitaria de Ciencias de la salud, Bogotá, Distrito Capital de Bogota, Colombia, 3Fundacion universitaria de ciencia de la Salud, Bogota, Distrito Capital de Bogota, Colombia

    Background/Purpose: Nailfold capillaroscopy is a fundamental tool in rheumatology for assessing capillary morphology, allowing the differentiation between primary and secondary Raynaud’s phenomenon, identifying risks associated…
  • Abstract Number: 0549 • ACR Convergence 2025

    High Prevalence of Obstructive Sleep Apnea in Psoriatic Arthritis: A Polysomnography-Based Cross-Sectional Study

    Suzan Attar1, Siraj Walli2, Yasser Bawazir3, Mohammad Mustafa4, Ayah Boudal5, Faris alhejailli2, Ahmad Bamagoos2 and Omar Kanbr2, 1King Abdulaziz University, Saudi Arabia, Jeddah, Saudi Arabia, 2KAU, Jeddah, Saudi Arabia, 3King Abdulaziz University, Jeddah, Saudi Arabia, 4Jeddah University, Jeddah, Saudi Arabia, 5King Abdullah Medical Complex, Jeddah, Saudi Arabia

    Background/Purpose: Background: Obstructive sleep apnea (OSA) is increasingly recognized in patients with psoriatic arthritis (PsA), yet few studies have used polysomnography (PSG)—the gold-standard diagnostic method.…
  • Abstract Number: 0736 • ACR Convergence 2025

    Effectiveness of Tocilizumab in strokes in patients with giant cell arteritis. Spanish multicenter study of clinical practice

    Ana Serrano-Combarro1, Javier Loricera2, Clara Moriano3, Santos Castañeda4, Javier Narváez5, Vicente Aldasoro Cáceres6, Rafael B. Melero-González7, Isabel De la Morena8, Ivan Ferraz Amaro9 and Ricardo Blanco10, 1Division of Rheumatology, Hospital Universitario Marques de Valdecilla, IDIVAL, Inmunopathology group, Santander, Santander, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, Spain, 3Hospital León, LEON, Castilla y Leon, Spain, 4Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Madrid, Spain, 5Hospital Universitario de Bellvitge, Barcelona, Spain, 6Hospital Universitario de Navarra, Pamplona, Spain, 7COMPLEXO HOSPITALARIO UNIVERSITARIO DE OURENSE, O Carballino, Spain, 8HOSPITAL CLINICO UNIVERSITARIO DE VALENCIA, VALENCIA, Spain, 9Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 10Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain

    Background/Purpose: Stroke is a feared complication of giant cell arteritis (GCA). Tocilizumab (TCZ) has shown efficacy and safety in large-vessel vasculitis (LVV) including GCA. Our…
  • Abstract Number: 0730 • ACR Convergence 2025

    Levels of Disease Activity and Their Relationship With Health-Related Quality of Life In ANCA-Associated Vasculitis Patients: Data from the Almenara Vasculitis Cohort

    Victor Pimentel-Quiroz1, Alvaro Oyarce-Calderón2, Allison Figueroa-Sánchez3, Leonor León-Yaurimucha3, Rocío Gamboa-Cárdenas4, Zoila Rodríguez-Bellido5, Risto Perich-Campos6, Graciela Alarcón7 and Manuel Ugarte-Gil8, 1Universidad Científica del Sur, San Isidro, Peru, 2Hospital Nacional Guillermo Almenara Irigoyen, San Miguel, Lima, Peru, 3Universidad Científica del Sur, Lima, Peru, 4Universidad Científica del Sur, Lima, Peru, 5Hospital Nacional Guillermo Almenara Irigoyen; Universidad Nacional Mayor de San Marcos, Lima, Peru, 6Hospital Nacional Guillermo Almenara Irigoyen; Universidad Nacional Mayor de San Marcos, La Molina, Peru, 7The University of Alabama at Birmingham, Oakland, CA, 8Universidad Cientifica del Sur, Lima, Peru

    Background/Purpose: It is known that health-related quality of life (HRQoL) in patients with ANCA-associated vasculitis (AAV) is impaired. Categories of disease activity levels have been…
  • Abstract Number: 0745 • ACR Convergence 2025

    Prevalence and Clinical Significance of Low ESR and CRP in Giant Cell Arteritis: A Population Based Study

    Eugenio de Miguel, Natalia López-Juanes, Maria-Eugenia Miranda-Carus, Carlota Ureta, Chamaida Plasencia-Rodríguez and Irene Monjo Henry, Hospital Universitario La Paz, Madrid, Spain

    Background/Purpose: Traditionally, elevated erythrocyte sedimentation rate (ESR) or C-reactive protein (CRP) had been considered a hallmark of GCA and both are included in the 2022…
  • Abstract Number: 0735 • ACR Convergence 2025

    A Real-World Study from the Greater Paris Clinical Data Warehouse

    Aïcha Kante1, Olivier Hassanaly2, Geoffroy Peyrac3, David Saadoun4, Cacoub Patrice4, Alexis REGENT5, Benjamin Terrier6, Luc Mouthon7, Arsène Mekinian8, Karim Sacré9, Jean-François Alexandra10, Sébastien Abad11, Robin Dhote11, Cécile goujard12, Damien Sène13, Stéphane Mouly14, Baptiste Hervier15, Olivier Bory16, Elisabeth Aslangul16, Isabelle Mahé16, Anne Couvelard17, Yann Nguyen18, Agnès Lefort18, Sophie georgin-Lavialle19, Olivier Steichen19, Viet-Thi Tran20 and Cloé Comarmond1, 1Department of Internal Medicine, Lariboisière University Hospital, Université Paris Cité, Assistance Publique Hôpitaux de Paris, INSERM U942, Paris, France, 2Unité de recherche clinique, AP-HP, Hôpital Saint Louis, F75010, Paris, France, Paris, France, 3Department of Internal Medicine, Lariboisière University Hospital, Université Paris Cité, AP-HP, Paris, France, 4Department of Internal Medicine and Clinical Immunology, Sorbonne Universités, AP-HP, Groupe Hospitalier Pitié-Salpêtrière, Centre national de références Maladies Autoimmunes et systémiques rares, Centre national de références Maladies Autoinflammatoires rares et Amylose inflammatoire (CEREMAIA), INSERM, UMR S959, Immunology-Immunopathology-Immunotherapy (I3), Paris, France, Paris, France, 5Hopital Cochin, Paris, France, 6Cochin Hospital, Paris, France, 7Department of Internal Medicine, National Referral Center for Rare Systemic Autoimmune Diseases, Cochin University Hospital, Université Paris Cité, AP-HP, Paris, France, 8Department of Internal Medicine, Inflammation-Immunopathology-Biotherapy Department (DMU i3), Saint-Antoine University Hospital, 75012 Paris, France, Paris, France, 9Department of Internal Medicine, Bichat University Hospital, Université Paris Cité, AP-HP, Paris, France, Paris, France, 10Internal Medicine, Hôpital Bichat, APHP, Paris, France, 11Service de Médecine Interne, Hôpital Avicenne, Assistance Publique-Hôpitaux de Paris (AP-HP); Université Paris 13, Sorbonne Paris Cité, Bobigny, France, Bobigny, France, 12Université Paris Saclay, Department of Internal Medicine and Clinical Immunology, Bicêtre Hospital, APHP, UMR1184 Inserm, CEA, Le Kremlin Bicêtre, France, Kremlin Bicêtre, France, 13Department of Internal Medicine, Lariboisière University Hospital, Université Paris Cité, Assistance Publique Hôpitaux de Paris, Paris, Ile-de-France, France, 14Department of Internal Medicine, Lariboisière University Hospital, Université Paris Cité, Assistance Publique Hôpitaux de Paris, Paris, France, 15Internal Medicine Department, Hôpital Saint-Louis, AP-HP, Université Paris Cité, Paris, France., Paris, France, 16Department of Internal Medicine, Louis-Mourier Hospital, AP-HP, Colombes, France, Colombes, France, 17Pathology Department, Bichat and Beaujon Hospitals, AP-HP, FHU MOSAIC, Université Paris Cité, Paris, France, Paris, France, 18Department of Internal Medicine, Beaujon Hospital, AP-HP Nord, Université Paris Cité, Clichy, France, Clichy, France, 19Sorbonne university, Tenon hospital, DMU3ID, CEREMAIA, ERN RITA, Paris, France, 20Université Paris Cité and Université Sorbonne Paris Nord, Inserm, INRAe, Centre for Research in Epidemiology and Statistics (CRESS), Paris; and Centre d'Epidémiologie Clinique, Hôpital Hôtel-Dieu, AP-HP, Paris, France, Paris, France

    Background/Purpose: Giant cell arteritis (GCA) relapses are frequent and often require therapeutic intensification in the form of glucocorticoids (GC) increase. GCA management has significantly evolved…
  • Abstract Number: 0758 • ACR Convergence 2025

    Association Between Baseline IL-6 Levels and the Clinical Phenotype of Giant Cell Arteritis

    Raquel Ugena-García1, Clara Churtichaga Domenech2, Judith Vidal-Ripoll2, Francina salabert-Carreras2, Cristina Calomarde-Gómez1, Cristina Rocamora-Gisbert3, Irene Peralta-García4, Niccolo Viveros2, Anne Riveros Frutos3, Ivette Casafont-Solé1 and Judit Font-Urgelles1, 1Hospital Universitari Germans Trias i Pujol, Badalona, Spain, 2Hospital Germans Trias i Pujol, Barcelona, 3Hospital Germans Trias i Pujol, Barcelona, Spain, 4Karolinska Institutet, Clinical Epidemiology Division, Department of Medicine Solna. Karolinska University Hospital, Medical Unit of Gastroenterology, Dermatology, Rheumatology. Theme Inflammation and Ageing, Stockholm, Sweden

    Background/Purpose: Giant cell arteritis (GCA) is the most common form of vasculitis in patients over the age of 50. Interleukin-6 (IL-6) has been shown to…
  • Abstract Number: 0773 • ACR Convergence 2025

    Clinical Significance of Anti-MDA5 Epitope Antibodies as Prognostic Indicators for Interstitial Lung Disease With or Without Dermatomyositis

    Tsuneo Sasai1, Ran Nakashima2, Motohiro Nonaka3, Norimichi Nomura4, Atsubumi Ogawa1, Yasuhiro Nohda1, Mirei Shirakashi2, Ryosuke Hiwa1, Hideaki Tsuji1, Hajime Yoshifuji2, Shogo Matsuda5, Masao Katsushima6, Michinori Ishitoku7, Yusuke Yoshida7, Yasuyuki Todoroki8, Satoshi Kubo9, Tomohiro Handa10, Hiromi Tomioka11, Ryo Tachikawa12, Keisuke Tomii12, Kiminobu Tanizawa13, Toru Arai14, Takuya Kotani15, Motomu Hashimoto16, Shintaro Hirata7, Yoshiya Tanaka17, Tsuneyo Mimori18 and Akio Morinobu19, 1Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 2Department of Rheumatology and Clinical Immunology, Graduate School of Medicine, Kyoto University, Kyoto, Kyoto, Japan, 3Department of Human Health Sciences, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 4Department of Cell Biology, Graduate School of Medicine, Kyoto University, Kyoto, Japan, 5Department of Internal Medicine IV, Division of Rheumatology, Osaka Medical and Pharmaceutical University, Osaka, Japan, 6Department of Clinical Immunology, Osaka Metropolitan Graduate School of Medicine, Osaka, Japan, 7Department of Clinical Immunology and Rheumatology, Hiroshima University Hospital, Hiroshima, Japan, 8Department of Molecular Targeted Therapies, University of Occupational and Environmental Health, Kitakyushu, Japan, 9Department of Molecular Targeted Therapies (DMTT), University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 10Department of Advanced Medicine for Respiratory Failure and Graduate School of Medicine, Kyoto University, Kyoto, Japan, 11Department of Respiratory Medicine, Kobe City Medical Center West Hospital, Kobe, Japan, 12Department of Respiratory Medicine, Kobe City Medical Center General Hospital, Kobe, Japan, 13Respiratory Medicine, National Hospital Organization Kyoto Medical Center, Kyoto, Japan, 14Clinical Research Center, NHO Kinki-Chuo Chest Medical Center, Sakai, Japan, 15Division of Rheumatology, Department of Internal Medicine IV, Osaka Medical and Pharmaceutical University, Osaka, Japan, 16Osaka Metropolitan University, Osaka, Japan, 17University of Occupational and Environmental Health, Japan, Kitakyushu, Japan, 18Takeda Clinic for Rheumatic Diseases, Kyoto, Japan, 19Kyoto University, Kyoto, Kyoto, Japan

    Background/Purpose: Melanoma differentiation-associated gene 5 (MDA5) is a cytoplasmic RNA sensor and activates the innate immune response. Autoantibodies against MDA5 are associated with rapidly progressive…
  • Abstract Number: 0764 • ACR Convergence 2025

    Frequency of large vessel vasculitis in giant cell arteritis with and without adventiitis of temporal artery – Is the presence of temporal arteritis sufficient to diagnose giant cell arteritis?-

    Yoichiro Akiyama, Jun Nakamura, Ayako Kokuzawa, Hiroi Kusaka, Sho Tani, Fuminori Taniguchi, Kohei Morikawa, Haruka Kondo, Shotaro Yamamoto, Yasuyuki Kamata and Kojiro Sato, Jichi Medical University, Shimotsuke, Tochigi, Japan

    Background/Purpose: Takayasu arteritis (TAK) and giant cell arteritis (GCA) belong to the large vessel vasculitis group. Differences between the two diseases have been reported based…
  • Abstract Number: 0739 • ACR Convergence 2025

    Tocilizumab in Giant Cell Arteritis with ischemic vs non-ischemic manifestations

    Carmen Secada-Gómez1, Javier Loricera2, Clara Moriano3, Santos Castañeda4, Javier Narváez5, Vicente Aldasoro Cáceres6, Olga Maiz7, Rafael B. Melero-González8, Paloma Vela Casasempere9, Susana Romero-Yuste10, Jose Luis Callejas11, Eugenio de Miguel12, Eva Galíndez Agirregoikoa13, Francisca Sivera14, Ivan Ferraz Amaro15, Julio Sánchez Martín16 and Ricardo Blanco1, 1Rheumatology Division, Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander, Spain, Santander, Cantabria, Spain, 2Hospital Universitario Marqués de Valdecilla, IDIVAL, Immunopathology Group, Santander , Spain, Santander, Spain, 3Hospital León, LEON, Castilla y Leon, Spain, 4Hospital Universitario de La Princesa, IIS-Princesa, Madrid, Madrid, Spain, 5Hospital Universitario de Bellvitge, Barcelona, Spain, 6Hospital Universitario de Navarra, Pamplona, Spain, 7Hospital Universitario de Donosti, Donostia, Spain, 8COMPLEXO HOSPITALARIO UNIVERSITARIO DE OURENSE, O Carballino, Spain, 9Hospital General Universitario Alicante, Alicante, Comunidad Valenciana, Spain, 10University Hospital Complex of Pontevedra, Pontevedra, Spain, 11Department of Internal Medicine, Hospital San Cecilio, Granada, Spain, 12Hospital Universitario La Paz, Madrid, Spain, 13BASURTO UNIVERSITY HOSPITAL, BILBAO, Spain, 14Hospital General Universitario Elda, Elda, Spain, 15Hospital Universitario de Canarias, Santa Cruz de Tenerife, Spain, 16Hospital Universitario 12 de Octubre, Madrid, Spain

    Background/Purpose: Tocilizumab (TCZ) is the only approved biological drug in the treatment of giant cell arteritis (GCA). However, there are no comparative studies on the…
  • Abstract Number: 0751 • ACR Convergence 2025

    Impact of Treatment with Upadacitinib on Biomarkers Identified by Proteomics in Giant Cell Arteritis

    Lisa Christ1, Shalina Taylor2, Yilin Xu2, Rhiya Sharma2, Thierry Sornasse2, Yingtao Bi2, Heath Guay2, Arathi Setty3, Ana Romero4, Peter Merkel5, Eugenio de Miguel6, Christian Dejaco7 and Cornelia Weyand8, 1Department of Rheumatology and Immunology, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Bern, Switzerland, 2AbbVie Inc, North Chicago, 3AbbVie Inc, North Chicago, IL, 4AbbVie, Barcelona, Spain, 5University of Pennsylvania, Philadelphia, PA, 6Hospital Universitario La Paz, Madrid, Spain, 7Medical University of Graz, Department of Rheumatology, Graz, Austria; Department of Rheumatology, Hospital of Brunico (SABES-ASDAA), Brunico, Italy, 8Division of Rheumatology, Department of Internal Medicine, Mayo Clinic, Rochester

    Background/Purpose: Interleukin-6 (IL-6) and interferon-gamma (IFNγ) have been identified as key drivers in the pathogenesis of giant cell arteritis (GCA), that promote disease progression. The…
  • Abstract Number: 0544 • ACR Convergence 2025

    Prevalence and Baseline Characteristics associated with Difficult-to-Manage Axial Spondyloarthritis in the DESIR Cohort

    Olivier Fakih1, Anna Molto2, Frank Verhoeven1, Clément Prati1 and WENDLING Daniel1, 1CHU de Besançon, Besançon, Franche-Comte, France, 2Assistance Publique Hôpitauxde Paris, Paris, France

    Background/Purpose: Despite a choice of multiple targeted DMARDs, with different modes of action (MoA), a number of patients with axial spondyloarthritis (axSpA) have failed several…
  • Abstract Number: 0762 • ACR Convergence 2025

    Relapse rate, predictors of relapses and impact of introduction of interleukin-6-receptor inhibition on relapse rate in GCA- Data from the large REATS cohort from six vasculitis centers

    Verena Schoenau1, Giulia Corte2, Koray Tascilar3, Fabian Hartmann2, Sebastian Ott2, Wolfgang Schmidt4, Andreas Krause5, Pfeil Alexander6, Peter Oelzner6, Marc Schmalzing7, Matthias Fröhlich8, Michael Gernert8, Jörg Henes9, Nils Venhoff10, Bernhard Hellmich11, Bernhard Manger2, Georg Schett12 and Juergen Rech12, 1- Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany., Erlangen, Germany, 2- Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and Uniklinikum Erlangen, Erlangen, Germany, Erlangen, Germany, 3Department of Medicine 3 - Rheumatology and Immunology, Friedrich-Alexander-Universität Erlangen-Nürnberg and University Hospital Erlangen, Erlangen, Germany, 4Immanuel Krankenhaus Berlin, Medical Centre for Rheumatology Berlin-Buch; Waldfriede Hospital, Rheumatology, Berlin, Germany, 5Department of Rheumatology and Clinical Immunology, Immanuel Krankenhaus Berlin, Berlin, Germany, 6Department of Internal Medicine III, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany, 7Department of Medicine II, Rheumatology/ Immunology,University Hospital of Wuerzburg, Wuerzburg, Bayern, Germany, 8University Hospital of Wuerzburg, Department of Medicine II, Rheumatology/ Immunology, Wuerzburg, Germany, 9Department of Internal Medicine II, Hematology, Oncology, Clinical Immunology, and Rheumatology, University Hospital Tübingen, Tuebingen, Germany, 10University of Freiburg, Freiburg, Germany, 11Klinik für Innere Medizin, Rheumatologie, Pneumologie, Nephrologie und Diabetologie, Medius Kliniken, Akademisches Lehrkrankenhaus der Universität Tübingen, Kirchheim unter Teck, Germany, 12Uniklinikum Erlangen, Friedrich-Alexander-Universität Erlangen-Nürnberg, Germany, Erlangen, Germany

    Background/Purpose: The diagnosis and management of giant cell arteritis (GCA) has significantly evolved over the last decades, mainly due to advances in imaging techniques and…
  • Abstract Number: 0765 • ACR Convergence 2025

    Rural Access to Physical Therapy for Osteoarthritis Rehabilitation (RAPTOR): A Pilot Feasibility Study

    Allyn Bove, Emma Zavacky, Hallie Zeleznik, Christopher Bise, Charity Patterson, Bambang Parmanto and G Kelley Fitzgerald, University of Pittsburgh, Pittsburgh, PA

    Background/Purpose: Individuals who live in rural areas are more likely to experience knee osteoarthritis-related disability and less likely to be referred to physical therapy for…
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All abstracts accepted to ACR Convergence are under media embargo once the ACR has notified presenters of their abstract’s acceptance. They may be presented at other meetings or published as manuscripts after this time but should not be discussed in non-scholarly venues or outlets. The following embargo policies are strictly enforced by the ACR.

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