Abstracts Archive - Page 839 of 2607 - ACR Meeting Abstracts

Abstract Number: 0038 • ACR Convergence 2020
Protein Biomarkers May Differentiate Responders and Non-Responders to Adalimumab, a Tumour Necrosis Factor Inhibitor, in Ankylosing Spondylitis Patients – The Bioefficacy SpA Study
Ana Fernandes¹, Atlas Mashayekhi Sardoo², Miguel Bernardes³, Patrícia Pinto⁴, Helena Santos⁵, João Lagoas Gomes⁶, José Tavares-Costa⁷, José A. P. da Silva⁸, João Madruga-Dias⁹, Alexandra Bernardo¹⁰, Jean-Charles Gaillard¹¹, Lúcia Domingues¹², Sara Maia¹², Jean Armengaud¹¹, Jaime C. Branco¹³, Ana Varela Coelho¹⁴ and Fernando Pimentel-Santos¹⁵, ¹1.Instituto de Tecnologia Química e Biológica, Universidade NOVA de Lisboa; 2.Universidade de Trás-os-Montes e Alto Douro, Vila Real, Portugal, Oeiras, Portugal, ²3. CEDOC, NOVA Medical School, Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal, Lisbon, Portugal, ³4.Centro Hospitalar de S. João (Rheumatology Department) , Porto, Portugal, Porto, Portugal, ⁴5. Centro Hospitalar de Vila Nova de Gaia/Espinho (Rheumatology Department), Vila Nova de Gaia, Portugal, Vila Nova de Gaia, Portugal, ⁵6.Instituto Português de Reumatologia (Rheumatology Department), Lisboa, Portugal, Lisboa, Portugal, ⁶7.Hospital Egas Moniz (CHLO) (Rheumatology Department), Lisboa, Portugal, Lisboa, Portugal, ⁷8.Unidade Local de Saúde do Alto Minho (Rheumatology Department), Ponte de Lima, Portugal, Ponte de Lima, Portugal, ⁸9.Centro Hospitalar e Universitário Coimbra (Rheumatology Department), Coimbra, Portugal, Coimbra, Portugal, ⁹10.Centro Hospital Médio Tejo (Rheumatology Department), Torres Novas, Portugal, Dublin, Ireland, ¹⁰5.Centro Hospitalar de Vila Nova de Gaia/Espinho (Rheumatology Department), Vila Nova de Gaia, Portugal, Vila Nova de Gaia, Portugal, ¹¹11.Centre d énergie atomique (Laboratoire Innovations technologiques pour la Détection et le Diagnostic (Li2D), Service de Pharmacologie et Immunoanalyse (SPI)), Avignon, France, Avignon, France, ¹²3.CEDOC, NOVA Medical School. Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal, Lisboa, Portugal, ¹³3.CEDOC, NOVA Medical School, Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal; 7.Hospital Egas Moniz (CHLO) (Rheumatology Department), Lisboa, Portugal, Lisboa, Portugal, ¹⁴1.Instituto de Tecnologia Química e Biológica, Universidade NOVA de Lisboa, Oeiras, Portugal, Oeiras, Portugal, ¹⁵3.CEDOC, NOVA Medical School, Faculdade de Ciências Médicas da Universidade NOVA de Lisboa, Lisboa, Portugal; 7.Hospital Egas Moniz (CHLO) (Rheumatology Department), Lisboa, Portugal, Lisbon, Portugal
Background/Purpose: Axial Spondyloarthritis (AS) is amongst the most common forms of inflammatory arthritis. Widely used in the treatment of axSpA, adalimumab is an engineered antibody…
Abstract Number: 0039 • ACR Convergence 2020
Identification of a Regulatory Pathway Governing Expression of TRAF1 via a JIA-associated Non-coding Variant
Qiang Wang¹, Marta Martínez², Matthew Weirauch³ and Peter Nigrovic⁴, ¹Brigham and Women's Hospital, Boston, MA, ²Brigham and Women's Hospital, Boston, ³Cincinnati Children’s Hospital Medical Center/Univ of Cincinnati, 535 Terrace Ave, ⁴Division of Rheumatology, Inflammation and Immunity, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA; Division of Immunology, Boston Children's Hospital, Harvard Medical School, Boston, MA, USA, Boston
Background/Purpose: Over the past decade, genome-wide association studies (GWAS) have identified TRAF1/C5 locus as a risk locus for rheumatoid diseases including RA and JIA(Plenge, Seielstad…
Abstract Number: 0040 • ACR Convergence 2020
Whole Blood RNA Expression in Clinically Suspected Arthralgia Patients Shows a Potential Value in Prediction of Inflammatory Arthritis
Ellis Niemantsverdriet¹, Erik van den Akker¹, Debbie Boeters¹, Susan van den Eeden¹, Annemieke Geluk¹ and Annette van der Helm - van Mil², ¹Leiden University Medical Center, Leiden, Netherlands, ²Leiden University Medical Center, Erasmus Medical Center, Leiden, Netherlands
Background/Purpose: Rheumatoid arthritis (RA)-patients have differently expressed genes involved in cytokine/chemokine-mediated immunity compared to healthy controls, which are changed years before RA-diagnosis. It is unclear,…
Abstract Number: 0041 • ACR Convergence 2020
Association of the RPA3-UMAD1 Locus with Interstitial Lung Diseases Complicated with Rheumatoid Arthritis in Japanese
Yuya Shirai¹, Suguru Honda², Katsunori Ikari³, Masahiro Kanai⁴, Yoshito Takeda⁵, Yoichiro Kamatani⁶, Takayuki Morisaki⁷, Eiichi Tanaka⁸, Atsushi Kumanogoh⁹, Masayoshi Harigai¹⁰ and Yukinori Okada¹¹, ¹Osaka university, Suita, Japan, ²Tokyo Women's Medical University, Tokyo, Japan, ³Tokyo Women's Medical University, Shinjuku, Japan, ⁴Harvard Medical School, Boston, ⁵Osaka university, Osaka, ⁶Graduate School of Frontier Sciences, the University of Tokyo, Tokyo, Japan, ⁷The institute of Medical Science, the University of Tokyo, Tokyo, Japan, ⁸Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Tokyo, Japan, ⁹Osaka university, Osaka, Japan, ¹⁰Department of Rheumatology, Tokyo Women’s Medical University School of Medicine, Shinjuku-ku, Tokyo, Japan, ¹¹Osaka University Graduate School of Medicine, Osaka, Japan
Background/Purpose: The genetic background of rheumatoid arthritis-interstitial lung disease (RA-ILD) has been evaluated in Europeans, but little knowledge has been obtained in non-Europeans. In particular,…
Abstract Number: 0042 • ACR Convergence 2020
Racial and Ethnic Differences in a Multiple Biochemical Measure of Rheumatoid Arthritis Disease Activity
Rahaf Baker¹, Jonathan Graf², Laura Trupin², Sarah Goglin³, Patricia Katz⁴, Jennifer Barton⁵, Jean Liew⁶ and Katherine Wysham⁷, ¹Highland Hospital Internal Medicine, Oakland, CA, ²UCSF, San Francisco, CA, ³University of California San Francisco, Burlingame, CA, ⁴University of California, San Francisco, Novato, CA, ⁵VAPORHCS/OHSU, Portland, OR, ⁶University of Washington, Seattle, WA, ⁷VA Puget Sound/University of Washington, Seattle, WA
Background/Purpose: Although management of RA has improved greatly over the past two decades with the advent of novel therapeutics, racial/ethnic and socioeconomic disparities persist. Traditional…
Abstract Number: 0043 • ACR Convergence 2020
Geographical Disparity in Rheumatoid Arthritis Disease Burden Independent of Race/Ethnicity
Gail Kerr¹, Christopher Swearingen², Manuela Pedra-Nobre³, Dianne Wollaston⁴, Sawsan Najmey⁵, Cynthia Lawrence-Elliott⁶, Theresa Lawrence Ford⁶, Sharon Dowell⁷, Heather North⁸, Robin Dore⁹, Soha Dolatabadi¹⁰, Thaila Ramanujam¹¹, Anne Winkler¹², Stacy Kennedy¹³, Ilona Jileaeva¹⁴, Amina Richardson¹⁵, Jeffrey Kaine¹⁶ and Grace Wright¹⁷, ¹Washington DC VA Medical Center, Washington, DC, ²New York University, New York, NY, ³North Jersey Rheumatology Center, Westfield, NJ, ⁴Memorial Advanced Rheumatology, Inc, HOUSTON, TX, ⁵Midstate Rheumatology Center, Freehold, NJ, ⁶North Georgia Rheumatology Group, Lawrenceville, GA, ⁷Howard University, Washington, DC, ⁸Pardee UNC Rheumatology, Hendersonville, NC, ⁹Private practice, Tustin, CA, ¹⁰Soha Dolatabadi, MD, Los Angeles, CA, ¹¹Thaila Ramanujanm. M.D Inc, Santa Cruz, CA, ¹²Cox Medical Center, Springfield, MO, ¹³Rowan Diagnostic Clinic, Concord, NC, ¹⁴Howard University Hospital, Washington, DC, ¹⁵Howard University College of Medicine, Washington, DC, ¹⁶Sarasota Arthritis Center, Sarasota, FL, ¹⁷Association of Women in Rheumatology, New York, NY
Background/Purpose: In the US, health care systems vary, as does cost sharing and access to various RA therapies. However, the burden of RA – a…
Abstract Number: 0044 • ACR Convergence 2020
Characterization of Racial Disparities in Rheumatoid Arthritis Treatment Choice and Location of Care
Elston He¹, Eli Cornblath², Pratyusha Yalamanchi³, Alexis Ogdie², Joshua Baker² and Michael George², ¹Synovium, Inc., Philadelphia, PA, ²University of Pennsylvania, Philadelphia, PA, ³Michigan Medicine, Ann Arbor, MI
Background/Purpose: Racial disparities in access to care and treatment regimens exist but remain poorly characterized in the rheumatoid arthritis (RA) patient population. Previous studies using…
Abstract Number: 0045 • ACR Convergence 2020
Healthcare Practitioner Confidence Assessing Rashes in Patients of Skin of Color with Lupus
Vijay Kannuthurai¹, Jacob Murray², Lisa Zickuhr³ and Ling Chen², ¹Washington University in St. Louis School of Medicine, Hazlehurst, MS, ²Washington University in St. Louis School of Medicine, St. Louis, MO, ³Washington University/B-JH/SLCH Consortium, St. Louis, MO
Background/Purpose: Medical education can promote bias that disproportionately affects patients of color. Patients of color with lupus are especially vulnerable as they often carry a…
Abstract Number: 0046 • ACR Convergence 2020
Socioeconomic Disparities in Functional Status Among RA Patients: A Longitudinal Analysis Using RISE Data
Jing Li¹, Gabriela Schmajuk², Michael Evans³, Zara Izadi⁴, Patricia Katz⁵, Alexis Ogdie⁶, Lisa Suter⁷ and Jinoos Yazdany³, ¹University of California, San Francisco, San Francisco, CA, ²University of California, San Francisco, Atherton, CA, ³Ucsf, San Francisco, CA, ⁴University of California San Francisco, San Francisco, CA, ⁵University of California, San Francisco, Novato, CA, ⁶Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, ⁷Yale School of Medicine, New Haven, CT
Background/Purpose: Prior studies have shown that RA outcomes, including disease activity, erosions, and disability, are worse among patients with low socioeconomic status (SES). However, few…
Abstract Number: 0047 • ACR Convergence 2020
Administrative Barriers to Enrollment of Ethnic Minorities in Clinical Research of Rheumatic/Immune-Mediated Diseases
Brittany Banbury¹, Sharon Dowell¹, Gail Kerr², Mercedes Quinones², Ginette Okoye¹ and Ilona Jileaeva¹, ¹Howard University Hospital, Washington, DC, ²Washington DC VA Medical Center, Washington, DC
Background/Purpose: Inclusion of ethnic minority subsets in clinical research remains subpar despite mandates for increased participation. Lack of trust, cultural sensitivity and bias, stereotyping, health…
Abstract Number: 0048 • ACR Convergence 2020
Determinants of Participation in Clinical Trials Among Patients with Lupus in the United States
Onengiya Harry¹, Carl Langefeld², Miranda Marion³, Trent Younts³, Lori Crosby⁴, Mara Vitolins³ and Avani Modi⁴, ¹Wake Forest School of Medicine, Clemmons, NC, ²Wake Forest School of Medicine, Winston Salem, NC, ³Wake Forest School of Medicine, Winston-Salem, ⁴Cincinnati Children's Hospital Medical Center, Cincinnati
Background/Purpose: Patient and family participation in research is critical to improving health outcomes, and identifying factors that contribute to participation or lack of participation in…
Abstract Number: 0049 • ACR Convergence 2020
Disparities in Patient Portal Use Among Patients with Rheumatic and Musculoskeletal Diseases in a Large Academic Medical Center
Enid Sun¹, Carolina Alvarez², Leigh Callahan³ and Saira Sheikh⁴, ¹Division of Rheumatology, Allergy and Immunology, University of North Carolina, Durham, NC, ²University of North Carolina at Chapel Hill Thurston Arthritis Research Center, Miami, FL, ³University of North Carolina Thurston Arthritis Research Center, Chapel Hill, NC, ⁴Division of Rheumatology, Allergy and Immunology, University of North Carolina, Chapel Hill, NC
Background/Purpose: Many aspects of rheumatic and musculoskeletal disease (RMD) management require a high level of patient agency and open avenues for patient-provider contact. In the…
Abstract Number: 0050 • ACR Convergence 2020
Demographic Disparities in the Medically Underserved Populations of Southern California: A Rheumatology Cohort of Cytokine Release Syndrome Patients Due to COVID-19
Muntarin Karim¹, Patil Injean², Sandy Lee², Neha Chiruvolu³, Loomee Doo⁴, Deepa Panikkath², Donna Jose⁵, Micah Yu⁴, Anna Lafian⁴, Vaneet Sandhu⁶, Karina Torralba⁷, Christina Downey², Mehrnaz Hojjati⁴ and Marven Cabling⁴, ¹Loma Linda University Health System, Loma Linda, CA, ²Loma Linda University Medical Center, Redlands, CA, ³UC Riverside School of Medicine, Riverside, CA, ⁴Loma Linda University Medical Center, LOMA LINDA, CA, ⁵Loma Linda University Medical Center, Ontario, CA, ⁶Loma Linda University, Loma Linda, CA, ⁷Loma Linda University School of Medicine, Redlands, CA
Background/Purpose: The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has led to the present coronavirus disease (COVID-19) pandemic. Multiple epidemiologic reports across the country show…
Abstract Number: 0051 • ACR Convergence 2020
COVID-Related Distress and Mental Health in Adult Rheumatology Patients During the COVID-19 Pandemic
Shereen Mahmood¹, Laura Curiel-Duran², Ruchika Darapaneni², Dalynah Maldonado², Lindsay Pattison², Emilee Tu² and Tamar Rubinstein³, ¹Albert Einstein College of Medicine / Montefiore Medical Center, Wantagh, NY, ²Albert Einstein College of Medicine / Montefiore Medical Center, Bronx, NY, ³Albert Einstein College of Medicine / Montefiore Medical Center, White Plains, NY
Background/Purpose: The novel coronavirus disease 2019 (COVID-19) pandemic has significantly affected all aspects of society, especially in the epicenters of New York City (NYC) and…
Abstract Number: 0052 • ACR Convergence 2020
Loneliness and Social Isolation Are Important Social Determinants Among Patients from Minority Communities with Rheumatic Diseases
Allen Anandarajah¹, Nancy Shelton², Leta Yi³, Meredith Graham⁴, Emily Papa⁵ and Robyn Carter⁵, ¹university of rochester medical center, rochesteruniversity, NY, ²Coordianted Care Services Inc, Rochester, NY, ³University of Rochester Medical Center, rochester, NY, ⁴Collaborative Health Research, Rochester, NY, ⁵St. Joseph's Neighbourhood Center, Rochester, NY
Background/Purpose: Loneliness and social isolation have detrimental effects on health and are associated with risk of an earlier death, depression and poor self-rated health. Few…

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